Lecture Exam 4 (Ch 12, 13, 14)

A  T-cell mediated

B  atopic

C  delayed

D  systemic anaphylactic

E  antibody mediated

A  maternal Rh ˗ cells enter an Rh + fetus

B  fetal Rh + cells enter an Rh + mother

C  maternal Rh + cells enter an Rh -fetus

D  fetal Rh ˗ cells enter an Rh + mother

E  fetal Rh + cells enter an Rh – mother

A  immunodeficiency

B  transfusion reaction

C  desensitization

D  autoimmune disease

E  hypersensitivity

A  humoralpathology

B  histopathology

C  epidemiology

D  hemopathology

E  immunopathology

A  foreign cells

B  IgE

C  complement

D  IgM

E  IgG

A  systemic lupus erythematosus

B  type I diabetes

C  metastatic cancer

D  rheumatic fever

E  Graves’ disease

A  allograft

B    

C  autograft

D  hypograft

E  isograft

F  xenograft

A  Inhalant

B  Injectant

C  Ingestant

D  Contactant

E  None of the choices are correct.

A  constriction of smooth muscle of bronchi and the intestine

B  relaxes vascular smooth muscle

C  wheal and flare reaction in skin

D  pruritus and headache

E  increased sensitivity to pain

A  type I only

B  type I, type II, and type III

C  type I, type II, type III, and type IV

D  type IV only

E  type I and type IV

A  a deficiency in T-cell development

B  graft rejection

C  a transfusion reaction

D  autoantibodies and T cells

E  IgE and mast cells

A  Rashes

B  Sneezing

C  Diarrhea

D  Contact dermatitis

E  Rhinitis

A  bind to histamine receptors on target organs

B  block synthesis of leukotrienes

C  inhibit the activity of lymphocytes

D  relieve inflammatory symptoms

E  reverse spasms of respiratory smooth muscles

A  Histamine acts on smooth muscle

B  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

C  Prostaglandins cause vasodilation and increased vascular permeability

D  Binding of IgE by the Fc region to mast cells and basophils

E  Degranulation

A  cells in thyroid follicles

B  sodium pump proteins in the cell membrane

C  acetylcholine receptors on smooth muscle

D  acetylcholine receptors on skeletal muscle

E  myelin sheath cells of the nervous system

A  Involves an immune complex reaction

B  Antigen-antibody complexes are deposited in the basement membrane of epithelial tissues

C  Involves production of IgG and IgE antibodies

D  The Arthus reaction is a local response

E  Serum sickness is a systemic response

A  atopic dermatitis

B  eczema

C  asthma

D  allergic rhinitis

E  anaphylaxis

A  Blood transfusion

B  Both skin graft and organ transplantation

C  Skin graft

D  All of thechoices are correct.

E  Organ transplantation

A  None of thechoices are correct.

B  degranulation

C  tissue matching

D  desensitization

E  sensitization

A  Histamine acts on smooth muscle

B  Prostaglandins cause vasodilation and increased vascular permeability

C  Degranulation

D  Binding of IgE by the Fc region to mast cells and basophils

E  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

A  Hypogammaglobulinemia

B  Host rejection of graft

C  None of the choices are correct.

D  Graft versus host disease

E  Formation of autoantibodies

A  Both anaphylaxis and antibody mediated

B  Anaphylaxis

C  Immune complex mediated

D  Antibody mediated

E  Both antibody mediated and immune complex mediated

A  myasthenia gravis

B  tuberculin reaction

C  Graves’ disease

D  rheumatoid arthritis

E  multiple sclerosis

A  platelet-activating factor

B  serotonin

C  prostaglandin

D  leukotriene

E  histamine

A  disulfide bonds between polypeptide chains

B  two identical heavy polypeptide chains

C  four antigen binding sites

D  two identical light polypeptide chains

E  a variable and constant region on each polypeptide chain

A  B cells maturing in bone marrow sites

B  release of mature lymphocytes to begin migration to various lymphoid organs

C  T cells maturing in the thymus

D  hormonal signals that initiate development

E  All of the choices are correct.

A  hinge

B  Fab

C  terminal

D  variable

E  Fc

A  activate B cells and other T cells

B  suppress immune reactions

C  function in allergic reactions

D  directly destroy target cells

E  secrete antibodies

A  engulf and modify antigen to be more immunogenic

B  include dendritic cells

C  All of the choices are correct.

D  hold and present processed antigen on their cell membrane surface

E  include macrophages

A  false

B  true

A  binding of T-cell to a site on the antigen

B  typically a protein antigen

C  interleukin-1 activating the T helper cell

D    

E  All of the choices are correct.

F  binding of T-cell to a class II MHC receptor on a macrophage

A  IgA

B  IgG

C  IgM

D  IgD

E  IgE

A  function in allergic reactions

B  activate B cells and other T cells

C  directly destroy target cells

D  secrete antibodies

E  suppress immune reactions

A  None of the choices are correct.

B  hapten

C  epitope

D  variable region

E  antigen binding site

A  aid in cellular development

B  All of the choices are correct.

C  function in recognition of self molecules

D  receive and transmit chemical messages among other cells of the system

E  are the result of genetic expression

A  are foreign to the immune system

B  have molecular complexity

C  have large polymers made up of repeating subunits

D  are large molecules with a minimum molecular weight of 1,000

E  are cells or large, complex molecules

A  autoantigens

B  allergens

C  superantigens

D  None of the choices are correct.

E  heterophilic antigens

A  natural killer (NK) cells

B  delayed hypersensitivity T cells

C  helper T cells

D  cytotoxic T cells

E  suppressor T cells

A  Helper T cells

B  Cytotoxic T cells

C  B cells

D  Antigen-presenting cells

E  Plasma cells

A  All of the choices are correct.

B  self receptors recognized by T lymphocytes

C  receptors located primarily on macrophages and B cells

D  all HLA antigens

E  certain secreted complement components

A  true

B  false

A  can serve as a B-cell receptor

B  is the first class synthesized by a plasma cell

C  contains a central J chain

D  has 10 antigen binding sites

E  is a dimer

A  those that evoke allergic reactions

B  None of the choices are correct.

C  body tissues that the immune system mistakes as foreign

D  cell markers found in some member of a species but not in other members

E  bacterial toxins that activate T cells at a 100 times greater rate than other antigens

A  false

B  true

A  IgM

B  IgG

C  IgE

D  IgA

E  IgD

A  have membrane receptors that recognize foreign antigens

B  develop into clones of B and T cells with extreme variations of specificity

C  possess MHC antigens for recognizing self

D  gain tolerance to self by destruction of lymphocytes that could react against self

E  All of the choices are correct.

A  glycoproteins, called MHC antigens, found on all body cells

B  All of the choices are correct.

C    

D  located in the thymus gland

E  found on the third chromosome

F  a set of genes that code for MHC glycoproteins

A  red blood cells

B  eosinophils

C  epithelial cells

D  islet of Langerhans cells

E  leukocytes

A  IgM and IgD

B  IgD only

C  IgD and IgE

D  IgM only

E  IgG only

A  Respiratory tract

B  Urinary tract

C  Digestive tract

D  Skin

E  Eyes

A  increases the availability of iron

B  increases metabolism

C  reduces the ability of temperature-sensitive organisms to multiply

D  stimulates hematopoiesis

E  increases phagocytosis

A  Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

B  Involves barriers at portals of entry
Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

C  Includes chemicals such as lysozyme and lactic acid
Involves recognition of foreign agents by their pathogen-associated molecular patterns

D  Includes chemicals such as lysozyme and lactic acid
Involves barriers at portals of entry
Examples include the ciliated epithelium of the respiratory passages, excretion of urine, and production of tears

A  neutrophils

B  eosinophils

C  lymphocytes

D  monocytes

E  basophils

A  macrophages

B  primary phagocytes

C  cytotoxic T cells

D  neutrophils

E  killer T cells

A  platelets

B  mast cells

C  eosinophils

D  macrophages

E  dendritic cells

A  Monocytes

B  Lymphocytes

C  Neutrophils

D  Basophils

E  Eosinophils

A  swelling

B  chills

C  redness

D  pain

E  warmth

A  lysozyme

B  digestive enzymes

C  antibodies

D  histamine

E  antigens

A  leukocytes

B  agranulocytes

C  granulocytes

D  None of the choices are correct.

E  monocytes

A  Mobilize and attract immune components to injury site

B  Block further invasion

C  Destroy microbes

D  Cause a fever

E  Start tissue repair

A  migration of white blood cells from the blood out to the tissues

B  production of only red blood cells

C  production of white blood cells, red blood cells, and platelets

D  loss of blood due to hemorrhaging

E  plugging of broken vessels to stop bleeding

A  tears

B  unbroken skin

C  T cells

D  mucus

E  hairs

A  is the liquid portion of blood in which blood cells are suspended

B  contains fibrinogen

C  All of the choices are correct.

D  is mostly water

E  contains albumin and globulins

A  Calor—warmth

B  Rubor—redness

C  Tumor—cancer

D  None of these are mismatched.

E  Dolar—pain

A  Pyrogens cause vasodilation and increased capillary permeability.

B  Serotonin causes smooth muscle contraction.

C  It can last hours to years.

D  Fever could be beneficial to inhibiting the pathogen.

E  Basophils and mast cells release histamine.

A  eyes

B  urinary tract

C  skin

D  respiratory tract

E  digestive tract

A  Bloodstream

B  Lymphatic system

C  Intracellular fluid

D  Extracellular fluid

A  B cells; neutrophils

B  B cells; T cells

C  Monocytes; basophils

D  T cells; B cells

E  Basophils; T cells

A  Develop from undifferentiated stem cells

B  Include erythrocytes that, when mature, lose their nuclei

C  Include Kupffer cells

D  After birth, produced in red bone marrow sites

E  Include leukocytes that are either granulocytes or agranulocytes

A  motility

B  vasodilation

C  diapedesis

D  chemotaxis

E  phagocytosis

A  GALT

B  lymph nodes

C  thymus

D  spleen

E  tonsils

A  Host defenses due to B and T cells and their products
Use of drugs and antibiotics
Anatomical and physiological barriers

B  Internal cellular and chemical defenses
Phagocytosis and inflammation
Anatomical and physiological barriers

C  Host defenses due to B and T cells and their products
Use of drugs and antibiotics

D  Internal cellular and chemical defenses
Use of drugs and antibiotics
Host defenses due to B and T cells and their products

A  destroys pathogens

B  None of the choices are correct.

C  creates a physical barrier against pathogens

D  physically restricts pathogens to a specific region

E  is toxic to pathogens