Module 6 Quiz

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Question #1

What is the percent transferrin saturation given the following data: serum iron 150 μg/dL, TIBC 350 μg/dL, transferrin 300 mg/dL, and ferritin 65 ng/mL?

A 55%

B 233%

C 43%

D 500%

Question #2

The two pairs of globin chains in normal HbA hemoglobin are

A beta and gamma.

B alpha and gamma.

C alpha and beta.

D beta and delta.

Question #3

The major substance formed from the breakdown of hemoglobin when senescent red blood cells are phagocytized by the reticuloendothelial system is

A bilirubin.

B urobilinogen.

C myoglobin.

D urobilin.

Question #4

What soluble iron-protein complex is the form in which iron is stored in tissues?

A Hemoglobin

B Transferrin

C Ferritin

D Hemosiderin

Question #5

The most common cause of iron deficiency anemia in children is

A megaloblastic anemia.

B bleeding ulcers.

C hemolytic anemias.

D dietary deficiency.

Question #6

Regarding serum iron analysis, the maximum concentration of iron that transferrin can bind is reflected in what laboratory measurement?

A Total iron-binding capacity (TIBC)

B Serum iron

C Transferrin saturation

D Hemoglobin

Question #7

In a certain hemoglobin structural variant, a deletion in the coding gene results in a reduction of the production of the beta globin chain. This will result in

A decreased quantity of HbA.

B hemolysis of red blood cells due to unstable hemoglobin.

C a sickling disorder due to insoluble hemoglobin.

D an α-thalassemia due to overproduction of alpha-globin chains.

Question #8

The inherited disorders caused by an underproduction of certain globin chains are referred to as the

A hemoglobin variant disorders.

B hemoglobinopathies.

C iron deficiency disorders.

D thalassemias.

Question #9

A 65-year-old woman was admitted to the hospital in mild congestive heart failure. She complained of a burning sensation in her calves and feet and of weight loss. Upon admission she appeared confused, depressed, and pale. She had some edema around her ankles. Her lab results were as follows: low hemoglobin and hematocrit, increased RBC size, decreased RBC and WBC count, and hypersegmented neutrophils. All basic chemistry values were normal. Which vitamin should be tested for deficiency?

A Vitamin A

B Vitamin D

C Vitamin C

D Vitamin B12

Question #10

Which vitamin is given to a newborn within minutes of birth?

A D

B K

C A

D B12

Question #11

A 10-year-old girl visits her pediatrician. The physician notes that the girl has immature secondary sex characteristics and small stature. Her mother who has accompanied her complains that the adolescent also exhibits very slow healing of cuts and scrapes and has had some hair loss. Your laboratory has ruled out any inborn error of metabolism and possible cancer. Deficiency of what trace element might be responsible for the stated symptoms?

A Chromium

B Selenium

C Zinc

D Copper

Question #12

What is the common cause of vitamin B12 deficiency?

A Pernicious anemia

B Scurvy

C Rickets

D Hyperkeratosis

Question #13

Absorption of vitamin B12 requires the presence of

A vitamin C.

B folic acid.

C intrinsic factor.

D insulin.

Question #14

The most commonly used method of analysis for assessing vitamins A, K, and B6 is

A high-performance liquid chromatography (HPLC).

B immunoassay.

C spectrophotometry.

D competitive protein binding.

Question #15

Scurvy is associated with deficiency of which one of the following vitamins?

A C

B D

C B12

D A

Question #16

The half-life of a protein hormone in plasma is

A long, usually greater than 90 minutes.

B long, at least 24 hours.

C short, approximately 10–30 minutes.

D short, more than 1 hour but less than 3 hours.

Question #17

Which of the following protein hormones produces a decrease in blood glucose by causing glucose to enter cells for energy production?

A Thyroid hormone

B Insulin

C Cortisol

D Aldosterone

Question #18

Which one of the following statements concerning steroid hormones is correct?

A Steroid hormones attach to a receptor on the surface of a cell, which eventually induces enzyme phosphorylation within the cell.

B Steroid hormones have a very short half-life (usually <30 minutes) in the circulation.

C Steroid hormones are hydrophobic when free and bind to intracellular receptors in the nucleus.

D Steroid hormones, because of their structure, are not bound to carrier proteins as they circulate in the blood.

Question #19

As part of homeostatic control by hormones, the metabolism of electrolytes and water balance is controlled in part by the renal system. What hormone synthesized by the kidneys affects water and electrolyte balance?

A Aldosterone

B Renin

C Insulin

D Vasopressin; antidiuretic hormone (ADH)

Question #20

The release of thyroid-stimulating hormone (from the pituitary gland) stimulates the release of thyroid hormones from the thyroid gland. When the level of thyroid hormones increases in the circulation, they shut off the release of TSH from the pituitary. This is an example of which type of feedback?

A Positive feedback

B Open loop feedback

C Negative feedback

D None of the above

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