Amanda’s parents realized that her body was not developing properly about the time she was 12 years old. She was shorter than most of her friends and was not going through changes normally associated with female puberty. They took her to a doctor who initially diagnosed Amanda with Turner Syndrome because of her physical features. He ordered a karyotype that confirmed his diagnosis. Amanda was born with only one X chromosome. Although there is no specific cure, the doctor was able to treat her and correct some of the problems associated with the condition. For example, she received growth hormone to improve her growth and estrogen to help her develop the physical changes of puberty. In relation to sex chromosomes, Amanda would be designated as ______.