Mastery EAQ Ch. 2

A  Probenecid reduces allergic reactions to amoxicillin. Probenecid enhances the antibacterial action of amoxicillin. Probenecid prevents the renal excretion of amoxicillin.

B  Combination therapy is beneficial to the patient. Probenecid prevents the renal excretion of amoxicillin. Probenecid increases the duration of action of amoxicillin.

C  Probenecid reduces allergic reactions to amoxicillin. Probenecid increases the duration of action of amoxicillin. Probenecid enhances the antibacterial action of amoxicillin.

D  Probenecid reduces allergic reactions to amoxicillin. Probenecid enhances the antibacterial action of amoxicillin.

A  Empiric

B  Prophylactic

C  Supplemental

D  Maintenance

A  Development of drug toxicity

B  Delay in drug absorption

C  Shortened duration of drug actions

D  Decreased pharmacologic effects of drugs

A  Urticaria

B  Rash

C  Hypotension

D  Anaphylactic shock

A  Obtain a prescription for an oral formulation without altering the dose.
Explain to the patient that the drug becomes inactive if it is taken orally.

B  Explain to the patient that the drug causes toxic effects if it is taken orally.
Obtain a prescription for an oral formulation without altering the dose.

C  Explain to the patient that the drug becomes inactive if it is taken orally.
Explain to the patient that the drug will have a reduced effect if it is taken orally.

D  Obtain a prescription for an enteric-coated oral formulation to prevent inactivation in the liver.
Obtain a prescription for an oral formulation without altering the dose.

A  It will become zero.

B  It will be decreased.

C  It will be unaffected.

D  It will be increased.

A  Intranasal, Intraocular, and Transdermal

B  Intranasal, Injection into the portal vein and Oral

C  Injection into the portal vein and Oral

D  Injection into the portal vein and Transdermal

A  Administer the antibiotic with diuretic medications.

B  Initiate therapy with a lower-than-recommended dose.

C  Prescribe an antibiotic with a low therapeutic index.

D  Increase the dose from the recommended dose.

A  Yogurt

B  Grapefruit

C  Spinach

D  Cheese

A  Oral suspension

B  Elixir

C  Enteric-coated tablet

D  Capsule

A  Massaging the site after injection

B  Applying cold packs to the injection site

C  Lowering the extremity below the level of the heart

D  Administering the medication via the Z-track method

A  The therapeutic index of the drug may have been high.

B  The patient may have taken the drug with grapefruit juice.

C  The patient may have a deficiency of drug-metabolizing enzymes.

D  The patient may have taken an excess dose of the drug.

A  Warfarin

B  Amoxicillin

C  Acetaminophen

D  Ibuprofen

A  Palliative

B  Maintenance

C  Empiric

D  Prophylactic

A  Crush the capsule.

B  Chew the granules in the capsule.

C  Open the capsule and sprinkle the granules on soft food.

D  Dissolve the granules in a beverage.

A  “I should avoid giving the patient orange juice.”

B  “I should avoid giving the patient milk.”

C  “I should avoid giving the patient green leafy vegetables.”

D  “I should avoid giving the patient aged cheese.”

A  “Take the drug with iron-rich foods like spinach.”

B  “Avoid taking the drug with milk.”

C  “Take the drug with vitamin supplements.”

D  “Take an antacid with the drug.”

A  The chances of side effects are low with this drug relative to other drugs.

B  There is a high possibility that overdose events will occur.

C  The drug will have low tolerance when compared with other drugs.

D  There is less possibility of developing dependence.

A  Medications given orally bypass the portal circulatory system.

B  A large percentage of an intravenously administered drug is metabolized into inactive metabolites in the liver.

C  Drugs administered intravenously enter the portal system before systemic distribution.

D  Medications given intravenously are not affected by the first-pass effect.

A  Absorption of the drug in the intestine is prevented.The drug should be taken with large amounts of food.

B  The drug should be taken with large amounts of food. The drug should be crushed before administration.

C  Anticholinergic drugs may negate the effect of the enteric coating. Dissolution of the drug in the stomach is prevented.

D  The drug should be crushed before administration. Absorption of the drug in the intestine is prevented.

A  Bone marrow suppression

B  Hemolysis of platelets

C  Hemolysis of red blood cells

D  Hemolysis of white blood cells

A  It negates the action of the drug.

B  It increases excretion of the drug.

C  It chemically binds to the drug.

D  It reduces the metabolism of the drug.

A  10 mg/L

B  20 mg/L

C  50 mg/L

D  60 mg/L

A  75 mg/L

B  40 mg/L

C  50 mg/L

D  25 mg/L

A  Subcutaneously

B  Intravenously

C  Intramuscularly

D  Intrathecally

A  Pharmacodynamics

B  Pharmacotherapeutics

C  Pharmaceutics

D  Pharmacokinetics

A  Receptor interaction

B  Enzyme interaction

C  Selective interaction

D  Nonselective interaction

A  Powder

B  Elixir

C  Oral soluble wafer

D  Suspension

A  Formation of inactive metabolites is high in feces.

B  Formation of inactive metabolites is low in the kidneys.

C  Formation of inactive metabolites is high in the liver.

D  Formation of active metabolites is high in bile.

A  Mucosal cells

B  Red blood cells

C  White blood cells

D  Platelets

A  Idiosyncratic

B  Allergic

C  Pharmacologic

D  Drug interaction

A  Supplemental

B  Palliative

C  Maintenance

D  Prophylactic

A  Interacting with receptors. Altering metabolic chemical processes. Inhibiting the action of a specific enzyme

B  Altering metabolic chemical processes. Inhibiting the action of a specific enzyme. Making the cell perform a new function

C  None of these

D  Altering metabolic chemical processes. Making the cell perform a new function

A  Rectal

B  Oral

C  Sublingual

D  Subcutaneous

A  Seizure disorder

B  Coronary artery bypass graft

C  Resection of the small intestine

D  Left lower leg amputation

A  Additive

B  Synergistic

C  Antagonistic

D  Adverse

A  The duration of action is typically short.

B  The risk of drug–drug interactions is increased.

C  The effect is decreased in patients with a low albumin level.

D  Administration with 8 ounces of water is required.

A  Ptyalin

B  P450 enzymes

C  Pancreatic lipase

D  Gastric lipase

A  Contraindication

B  Idiosyncratic reaction

C  Drug interaction

D  Allergy

A  Palliative

B  Supplemental

C  Acute

D  Maintenance

A  Distribution rates among various body compartments

B  Adverse reactions to medications

C  Interactions among various drugs

D  Physiologic interactions of drugs

A  Maintenance

B  Supplemental

C  Acute

D  Supportive

A  Additive

B  Incompatibility

C  Synergistic

D  Antagonistic

A  Be absorbed by the body

B  Exert a response

C  Reach a therapeutic level

D  Be eliminated by the body

A  Oral

B  Intravenous

C  Subcutaneous

D  Sublingual

A  60%

B  100%

C  70%

D  50%

A  Horse

B  Pig

C  Mouse

D  Rabbit

A  Tolerance

B  Dependence

C  Addiction

D  Therapeutic index

A  Metabolism

B  Dilution

C  Excretion

D  Absorption

A  Dermatologic

B  Immune

C  Circulatory

D  Nervous

A  Topical

B  Oral

C  Transdermal

D  Rectal