Mastery EAQ Ch. 2

A  Combination therapy is beneficial to the patient. Probenecid prevents the renal excretion of amoxicillin. Probenecid increases the duration of action of amoxicillin.

B  Probenecid reduces allergic reactions to amoxicillin. Probenecid increases the duration of action of amoxicillin. Probenecid enhances the antibacterial action of amoxicillin.

C  Probenecid reduces allergic reactions to amoxicillin. Probenecid enhances the antibacterial action of amoxicillin. Probenecid prevents the renal excretion of amoxicillin.

D  Probenecid reduces allergic reactions to amoxicillin. Probenecid enhances the antibacterial action of amoxicillin.

A  Maintenance

B  Empiric

C  Supplemental

D  Prophylactic

A  Delay in drug absorption

B  Shortened duration of drug actions

C  Development of drug toxicity

D  Decreased pharmacologic effects of drugs

A  Anaphylactic shock

B  Hypotension

C  Urticaria

D  Rash

A  Explain to the patient that the drug causes toxic effects if it is taken orally.
Obtain a prescription for an oral formulation without altering the dose.

B  Obtain a prescription for an enteric-coated oral formulation to prevent inactivation in the liver.
Obtain a prescription for an oral formulation without altering the dose.

C  Explain to the patient that the drug becomes inactive if it is taken orally.
Explain to the patient that the drug will have a reduced effect if it is taken orally.

D  Obtain a prescription for an oral formulation without altering the dose.
Explain to the patient that the drug becomes inactive if it is taken orally.

A  It will be unaffected.

B  It will be increased.

C  It will become zero.

D  It will be decreased.

A  Injection into the portal vein and Transdermal

B  Injection into the portal vein and Oral

C  Intranasal, Injection into the portal vein and Oral

D  Intranasal, Intraocular, and Transdermal

A  Prescribe an antibiotic with a low therapeutic index.

B  Administer the antibiotic with diuretic medications.

C  Initiate therapy with a lower-than-recommended dose.

D  Increase the dose from the recommended dose.

A  Yogurt

B  Spinach

C  Cheese

D  Grapefruit

A  Oral suspension

B  Capsule

C  Enteric-coated tablet

D  Elixir

A  Administering the medication via the Z-track method

B  Lowering the extremity below the level of the heart

C  Applying cold packs to the injection site

D  Massaging the site after injection

A  The patient may have taken the drug with grapefruit juice.

B  The patient may have taken an excess dose of the drug.

C  The therapeutic index of the drug may have been high.

D  The patient may have a deficiency of drug-metabolizing enzymes.

A  Warfarin

B  Ibuprofen

C  Acetaminophen

D  Amoxicillin

A  Empiric

B  Maintenance

C  Prophylactic

D  Palliative

A  Open the capsule and sprinkle the granules on soft food.

B  Dissolve the granules in a beverage.

C  Chew the granules in the capsule.

D  Crush the capsule.

A  “I should avoid giving the patient orange juice.”

B  “I should avoid giving the patient green leafy vegetables.”

C  “I should avoid giving the patient aged cheese.”

D  “I should avoid giving the patient milk.”

A  “Take an antacid with the drug.”

B  “Avoid taking the drug with milk.”

C  “Take the drug with iron-rich foods like spinach.”

D  “Take the drug with vitamin supplements.”

A  There is a high possibility that overdose events will occur.

B  The drug will have low tolerance when compared with other drugs.

C  The chances of side effects are low with this drug relative to other drugs.

D  There is less possibility of developing dependence.

A  Medications given intravenously are not affected by the first-pass effect.

B  Drugs administered intravenously enter the portal system before systemic distribution.

C  A large percentage of an intravenously administered drug is metabolized into inactive metabolites in the liver.

D  Medications given orally bypass the portal circulatory system.

A  Anticholinergic drugs may negate the effect of the enteric coating. Dissolution of the drug in the stomach is prevented.

B  The drug should be taken with large amounts of food. The drug should be crushed before administration.

C  Absorption of the drug in the intestine is prevented.The drug should be taken with large amounts of food.

D  The drug should be crushed before administration. Absorption of the drug in the intestine is prevented.

A  Hemolysis of platelets

B  Hemolysis of white blood cells

C  Bone marrow suppression

D  Hemolysis of red blood cells

A  It reduces the metabolism of the drug.

B  It negates the action of the drug.

C  It chemically binds to the drug.

D  It increases excretion of the drug.

A  20 mg/L

B  10 mg/L

C  50 mg/L

D  60 mg/L

A  50 mg/L

B  40 mg/L

C  75 mg/L

D  25 mg/L

A  Intrathecally

B  Intravenously

C  Intramuscularly

D  Subcutaneously

A  Pharmacodynamics

B  Pharmacokinetics

C  Pharmaceutics

D  Pharmacotherapeutics

A  Receptor interaction

B  Selective interaction

C  Enzyme interaction

D  Nonselective interaction

A  Powder

B  Oral soluble wafer

C  Suspension

D  Elixir

A  Formation of inactive metabolites is high in feces.

B  Formation of active metabolites is high in bile.

C  Formation of inactive metabolites is high in the liver.

D  Formation of inactive metabolites is low in the kidneys.

A  Platelets

B  Mucosal cells

C  Red blood cells

D  White blood cells

A  Allergic

B  Drug interaction

C  Idiosyncratic

D  Pharmacologic

A  Maintenance

B  Palliative

C  Supplemental

D  Prophylactic

A  Altering metabolic chemical processes. Making the cell perform a new function

B  Interacting with receptors. Altering metabolic chemical processes. Inhibiting the action of a specific enzyme

C  None of these

D  Altering metabolic chemical processes. Inhibiting the action of a specific enzyme. Making the cell perform a new function

A  Subcutaneous

B  Oral

C  Rectal

D  Sublingual

A  Seizure disorder

B  Resection of the small intestine

C  Left lower leg amputation

D  Coronary artery bypass graft

A  Adverse

B  Additive

C  Synergistic

D  Antagonistic

A  Administration with 8 ounces of water is required.

B  The effect is decreased in patients with a low albumin level.

C  The duration of action is typically short.

D  The risk of drug–drug interactions is increased.

A  Ptyalin

B  P450 enzymes

C  Gastric lipase

D  Pancreatic lipase

A  Allergy

B  Idiosyncratic reaction

C  Drug interaction

D  Contraindication

A  Maintenance

B  Supplemental

C  Acute

D  Palliative

A  Physiologic interactions of drugs

B  Interactions among various drugs

C  Adverse reactions to medications

D  Distribution rates among various body compartments

A  Maintenance

B  Acute

C  Supplemental

D  Supportive

A  Antagonistic

B  Incompatibility

C  Synergistic

D  Additive

A  Be eliminated by the body

B  Exert a response

C  Reach a therapeutic level

D  Be absorbed by the body

A  Sublingual

B  Intravenous

C  Subcutaneous

D  Oral

A  100%

B  70%

C  60%

D  50%

A  Pig

B  Mouse

C  Rabbit

D  Horse

A  Therapeutic index

B  Dependence

C  Tolerance

D  Addiction

A  Dilution

B  Metabolism

C  Excretion

D  Absorption

A  Immune

B  Nervous

C  Circulatory

D  Dermatologic

A  Topical

B  Transdermal

C  Oral

D  Rectal