Inflammation and Pain

A  Chemicals in cannabis activate CB1 and CB2 receptors, reducing pain transmission and inflammation, respectively

B  Chemicals in cannabis inhibit CB1 decreasing immune function

C  Chemicals in cannabis inhibit CB1 receptors, which decreases excitatory neurotransmission and thereby contributes to reduction of pain response

D  Chemicals in cannabis activate CB2 receptors, which inhibits cancer cell growth that is contributing to the patient’s pain

E  Chemicals in cannabis activate CB1 receptors decreasing inflammation

A  N-acetylcysteine

B  Glutathione

C  Naloxone

D  N-acetyl-p-benzoquinone imine

A  Capsaicin

B  Acetaminophen

C  Celecoxib

D  Naproxen

E  Morphine

A  When the drug is no longer taken, withdrawal symptoms occur

B  Compulsive drug seeking behavior

C  Physical symptoms that occur when a medication is abruptly discontinued

D  A higher dose is required to achieve the same effect as when the patient was initially started the medication

A  Methylnaltrexone

B  Tramadol

C  Codeine

D  Nalbuphine

A  Excruciating pain from a gentle slap on the back

B  Intense pain from mildly cold water

C  Pain from being brushed by a feather

D  Severe pain with movement, despite no injury

A  Nav1.9

B  Nav1.8

C  Nav1.3

D  Nav1.7

A  Nociceptors are sensitized by inflammatory molecules

B  Nociceptors are activated by inflammatory molecules

C  Nociceptors are activated and sensitized by inflammatory molecules

A  Neuropathic pain

B  Visceral pain

C  Breakthrough pain

D  Functional pain

A  Breakthrough pain

B  Neuropathic pain

C  Visceral nociceptive pain

D  Somatic nociceptive pain

A  Leukotriene inhibition

B  Lipoxygenase inhibition

C  Cyclooxygenase inhibition

D  Phospholipase A2 inhibition

A  Decreased activity of inositol triphosphate

B  Increased activity of diacylglycerol

C  Increased activity of phospholipase C

D  Decreased activity of adenylyl cyclase

A  Lipoxygenase

B  Prostaglandin E2

C  Thromboxane A2

D  Leukotrienes

A  Anti-inflammatory actions

B  Expression of adhesion molecules

C  Inhibition of angiogenesis

D  Fever initiation