Lecture Exam 4 (Ch 12, 13, 14)

A  antibody mediated

B  T-cell mediated

C  systemic anaphylactic

D  delayed

E  atopic

A  fetal Rh + cells enter an Rh + mother

B  maternal Rh + cells enter an Rh -fetus

C  fetal Rh ˗ cells enter an Rh + mother

D  fetal Rh + cells enter an Rh – mother

E  maternal Rh ˗ cells enter an Rh + fetus

A  immunodeficiency

B  hypersensitivity

C  desensitization

D  autoimmune disease

E  transfusion reaction

A  histopathology

B  immunopathology

C  epidemiology

D  humoralpathology

E  hemopathology

A  IgM

B  foreign cells

C  IgG

D  IgE

E  complement

A  rheumatic fever

B  systemic lupus erythematosus

C  type I diabetes

D  metastatic cancer

E  Graves’ disease

A  isograft

B  autograft

C  xenograft

D  hypograft

E  allograft

F    

A  Contactant

B  Ingestant

C  Injectant

D  Inhalant

E  None of the choices are correct.

A  pruritus and headache

B  increased sensitivity to pain

C  constriction of smooth muscle of bronchi and the intestine

D  wheal and flare reaction in skin

E  relaxes vascular smooth muscle

A  type I, type II, type III, and type IV

B  type I, type II, and type III

C  type IV only

D  type I and type IV

E  type I only

A  IgE and mast cells

B  a deficiency in T-cell development

C  a transfusion reaction

D  graft rejection

E  autoantibodies and T cells

A  Rhinitis

B  Diarrhea

C  Sneezing

D  Contact dermatitis

E  Rashes

A  block synthesis of leukotrienes

B  reverse spasms of respiratory smooth muscles

C  bind to histamine receptors on target organs

D  inhibit the activity of lymphocytes

E  relieve inflammatory symptoms

A  Degranulation

B  Histamine acts on smooth muscle

C  Prostaglandins cause vasodilation and increased vascular permeability

D  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

E  Binding of IgE by the Fc region to mast cells and basophils

A  acetylcholine receptors on smooth muscle

B  acetylcholine receptors on skeletal muscle

C  myelin sheath cells of the nervous system

D  cells in thyroid follicles

E  sodium pump proteins in the cell membrane

A  The Arthus reaction is a local response

B  Serum sickness is a systemic response

C  Involves production of IgG and IgE antibodies

D  Involves an immune complex reaction

E  Antigen-antibody complexes are deposited in the basement membrane of epithelial tissues

A  atopic dermatitis

B  allergic rhinitis

C  eczema

D  anaphylaxis

E  asthma

A  Blood transfusion

B  Both skin graft and organ transplantation

C  Skin graft

D  Organ transplantation

E  All of thechoices are correct.

A  sensitization

B  tissue matching

C  desensitization

D  degranulation

E  None of thechoices are correct.

A  Histamine acts on smooth muscle

B  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

C  Degranulation

D  Prostaglandins cause vasodilation and increased vascular permeability

E  Binding of IgE by the Fc region to mast cells and basophils

A  Graft versus host disease

B  Formation of autoantibodies

C  Hypogammaglobulinemia

D  Host rejection of graft

E  None of the choices are correct.

A  Both anaphylaxis and antibody mediated

B  Antibody mediated

C  Anaphylaxis

D  Both antibody mediated and immune complex mediated

E  Immune complex mediated

A  Graves’ disease

B  myasthenia gravis

C  tuberculin reaction

D  rheumatoid arthritis

E  multiple sclerosis

A  histamine

B  platelet-activating factor

C  prostaglandin

D  serotonin

E  leukotriene

A  a variable and constant region on each polypeptide chain

B  four antigen binding sites

C  two identical heavy polypeptide chains

D  two identical light polypeptide chains

E  disulfide bonds between polypeptide chains

A  All of the choices are correct.

B  hormonal signals that initiate development

C  T cells maturing in the thymus

D  release of mature lymphocytes to begin migration to various lymphoid organs

E  B cells maturing in bone marrow sites

A  Fc

B  variable

C  hinge

D  Fab

E  terminal

A  secrete antibodies

B  suppress immune reactions

C  directly destroy target cells

D  function in allergic reactions

E  activate B cells and other T cells

A  All of the choices are correct.

B  engulf and modify antigen to be more immunogenic

C  include dendritic cells

D  include macrophages

E  hold and present processed antigen on their cell membrane surface

A  false

B  true

A  binding of T-cell to a class II MHC receptor on a macrophage

B  interleukin-1 activating the T helper cell

C    

D  binding of T-cell to a site on the antigen

E  typically a protein antigen

F  All of the choices are correct.

A  IgM

B  IgA

C  IgE

D  IgG

E  IgD

A  secrete antibodies

B  function in allergic reactions

C  directly destroy target cells

D  activate B cells and other T cells

E  suppress immune reactions

A  None of the choices are correct.

B  epitope

C  variable region

D  hapten

E  antigen binding site

A  are the result of genetic expression

B  receive and transmit chemical messages among other cells of the system

C  aid in cellular development

D  function in recognition of self molecules

E  All of the choices are correct.

A  are large molecules with a minimum molecular weight of 1,000

B  have molecular complexity

C  are foreign to the immune system

D  have large polymers made up of repeating subunits

E  are cells or large, complex molecules

A  None of the choices are correct.

B  heterophilic antigens

C  autoantigens

D  superantigens

E  allergens

A  natural killer (NK) cells

B  helper T cells

C  cytotoxic T cells

D  delayed hypersensitivity T cells

E  suppressor T cells

A  Helper T cells

B  B cells

C  Antigen-presenting cells

D  Cytotoxic T cells

E  Plasma cells

A  certain secreted complement components

B  receptors located primarily on macrophages and B cells

C  self receptors recognized by T lymphocytes

D  all HLA antigens

E  All of the choices are correct.

A  true

B  false

A  is the first class synthesized by a plasma cell

B  has 10 antigen binding sites

C  is a dimer

D  contains a central J chain

E  can serve as a B-cell receptor

A  body tissues that the immune system mistakes as foreign

B  cell markers found in some member of a species but not in other members

C  those that evoke allergic reactions

D  bacterial toxins that activate T cells at a 100 times greater rate than other antigens

E  None of the choices are correct.

A  false

B  true

A  IgM

B  IgD

C  IgE

D  IgA

E  IgG

A  have membrane receptors that recognize foreign antigens

B  develop into clones of B and T cells with extreme variations of specificity

C  possess MHC antigens for recognizing self

D  gain tolerance to self by destruction of lymphocytes that could react against self

E  All of the choices are correct.

A  found on the third chromosome

B  glycoproteins, called MHC antigens, found on all body cells

C  located in the thymus gland

D  a set of genes that code for MHC glycoproteins

E    

F  All of the choices are correct.

A  epithelial cells

B  eosinophils

C  leukocytes

D  islet of Langerhans cells

E  red blood cells

A  IgM only

B  IgM and IgD

C  IgD only

D  IgG only

E  IgD and IgE

A  Digestive tract

B  Respiratory tract

C  Skin

D  Urinary tract

E  Eyes

A  increases the availability of iron

B  stimulates hematopoiesis

C  reduces the ability of temperature-sensitive organisms to multiply

D  increases metabolism

E  increases phagocytosis

A  Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

B  Includes chemicals such as lysozyme and lactic acid
Involves barriers at portals of entry
Examples include the ciliated epithelium of the respiratory passages, excretion of urine, and production of tears

C  Includes chemicals such as lysozyme and lactic acid
Involves recognition of foreign agents by their pathogen-associated molecular patterns

D  Involves barriers at portals of entry
Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

A  eosinophils

B  lymphocytes

C  monocytes

D  neutrophils

E  basophils

A  primary phagocytes

B  macrophages

C  neutrophils

D  cytotoxic T cells

E  killer T cells

A  platelets

B  eosinophils

C  macrophages

D  mast cells

E  dendritic cells

A  Eosinophils

B  Neutrophils

C  Basophils

D  Monocytes

E  Lymphocytes

A  pain

B  swelling

C  redness

D  warmth

E  chills

A  antibodies

B  antigens

C  histamine

D  lysozyme

E  digestive enzymes

A  leukocytes

B  granulocytes

C  None of the choices are correct.

D  monocytes

E  agranulocytes

A  Start tissue repair

B  Block further invasion

C  Destroy microbes

D  Cause a fever

E  Mobilize and attract immune components to injury site

A  production of only red blood cells

B  production of white blood cells, red blood cells, and platelets

C  loss of blood due to hemorrhaging

D  plugging of broken vessels to stop bleeding

E  migration of white blood cells from the blood out to the tissues

A  T cells

B  unbroken skin

C  hairs

D  tears

E  mucus

A  is mostly water

B  contains albumin and globulins

C  is the liquid portion of blood in which blood cells are suspended

D  contains fibrinogen

E  All of the choices are correct.

A  Dolar—pain

B  Tumor—cancer

C  Calor—warmth

D  Rubor—redness

E  None of these are mismatched.

A  Basophils and mast cells release histamine.

B  Serotonin causes smooth muscle contraction.

C  Fever could be beneficial to inhibiting the pathogen.

D  Pyrogens cause vasodilation and increased capillary permeability.

E  It can last hours to years.

A  skin

B  respiratory tract

C  eyes

D  digestive tract

E  urinary tract

A  Intracellular fluid

B  Lymphatic system

C  Bloodstream

D  Extracellular fluid

A  Basophils; T cells

B  T cells; B cells

C  Monocytes; basophils

D  B cells; neutrophils

E  B cells; T cells

A  Develop from undifferentiated stem cells

B  Include erythrocytes that, when mature, lose their nuclei

C  Include leukocytes that are either granulocytes or agranulocytes

D  After birth, produced in red bone marrow sites

E  Include Kupffer cells

A  phagocytosis

B  chemotaxis

C  diapedesis

D  vasodilation

E  motility

A  thymus

B  tonsils

C  spleen

D  lymph nodes

E  GALT

A  Internal cellular and chemical defenses
Phagocytosis and inflammation
Anatomical and physiological barriers

B  Internal cellular and chemical defenses
Use of drugs and antibiotics
Host defenses due to B and T cells and their products

C  Host defenses due to B and T cells and their products
Use of drugs and antibiotics

D  Host defenses due to B and T cells and their products
Use of drugs and antibiotics
Anatomical and physiological barriers

A  creates a physical barrier against pathogens

B  None of the choices are correct.

C  is toxic to pathogens

D  destroys pathogens

E  physically restricts pathogens to a specific region