Lecture Exam 4 (Ch 12, 13, 14)

A  atopic

B  antibody mediated

C  T-cell mediated

D  delayed

E  systemic anaphylactic

A  fetal Rh + cells enter an Rh – mother

B  fetal Rh ˗ cells enter an Rh + mother

C  maternal Rh + cells enter an Rh -fetus

D  maternal Rh ˗ cells enter an Rh + fetus

E  fetal Rh + cells enter an Rh + mother

A  immunodeficiency

B  autoimmune disease

C  hypersensitivity

D  desensitization

E  transfusion reaction

A  hemopathology

B  epidemiology

C  histopathology

D  humoralpathology

E  immunopathology

A  foreign cells

B  IgE

C  complement

D  IgG

E  IgM

A  systemic lupus erythematosus

B  type I diabetes

C  metastatic cancer

D  Graves’ disease

E  rheumatic fever

A  isograft

B  xenograft

C    

D  hypograft

E  allograft

F  autograft

A  Contactant

B  Injectant

C  None of the choices are correct.

D  Ingestant

E  Inhalant

A  constriction of smooth muscle of bronchi and the intestine

B  wheal and flare reaction in skin

C  relaxes vascular smooth muscle

D  increased sensitivity to pain

E  pruritus and headache

A  type I, type II, type III, and type IV

B  type I only

C  type IV only

D  type I and type IV

E  type I, type II, and type III

A  a deficiency in T-cell development

B  autoantibodies and T cells

C  a transfusion reaction

D  IgE and mast cells

E  graft rejection

A  Contact dermatitis

B  Rashes

C  Diarrhea

D  Sneezing

E  Rhinitis

A  bind to histamine receptors on target organs

B  inhibit the activity of lymphocytes

C  reverse spasms of respiratory smooth muscles

D  block synthesis of leukotrienes

E  relieve inflammatory symptoms

A  Histamine acts on smooth muscle

B  Degranulation

C  Binding of IgE by the Fc region to mast cells and basophils

D  Prostaglandins cause vasodilation and increased vascular permeability

E  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

A  sodium pump proteins in the cell membrane

B  cells in thyroid follicles

C  myelin sheath cells of the nervous system

D  acetylcholine receptors on smooth muscle

E  acetylcholine receptors on skeletal muscle

A  Antigen-antibody complexes are deposited in the basement membrane of epithelial tissues

B  Involves production of IgG and IgE antibodies

C  The Arthus reaction is a local response

D  Involves an immune complex reaction

E  Serum sickness is a systemic response

A  asthma

B  anaphylaxis

C  eczema

D  allergic rhinitis

E  atopic dermatitis

A  All of thechoices are correct.

B  Skin graft

C  Organ transplantation

D  Blood transfusion

E  Both skin graft and organ transplantation

A  tissue matching

B  sensitization

C  degranulation

D  None of thechoices are correct.

E  desensitization

A  Prostaglandins cause vasodilation and increased vascular permeability

B  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

C  Histamine acts on smooth muscle

D  Degranulation

E  Binding of IgE by the Fc region to mast cells and basophils

A  Formation of autoantibodies

B  Graft versus host disease

C  Hypogammaglobulinemia

D  None of the choices are correct.

E  Host rejection of graft

A  Antibody mediated

B  Immune complex mediated

C  Anaphylaxis

D  Both anaphylaxis and antibody mediated

E  Both antibody mediated and immune complex mediated

A  rheumatoid arthritis

B  Graves’ disease

C  myasthenia gravis

D  multiple sclerosis

E  tuberculin reaction

A  histamine

B  prostaglandin

C  leukotriene

D  serotonin

E  platelet-activating factor

A  four antigen binding sites

B  disulfide bonds between polypeptide chains

C  two identical light polypeptide chains

D  a variable and constant region on each polypeptide chain

E  two identical heavy polypeptide chains

A  hormonal signals that initiate development

B  release of mature lymphocytes to begin migration to various lymphoid organs

C  T cells maturing in the thymus

D  All of the choices are correct.

E  B cells maturing in bone marrow sites

A  variable

B  Fab

C  hinge

D  Fc

E  terminal

A  secrete antibodies

B  directly destroy target cells

C  activate B cells and other T cells

D  suppress immune reactions

E  function in allergic reactions

A  engulf and modify antigen to be more immunogenic

B  include dendritic cells

C  All of the choices are correct.

D  include macrophages

E  hold and present processed antigen on their cell membrane surface

A  true

B  false

A  typically a protein antigen

B  binding of T-cell to a site on the antigen

C    

D  All of the choices are correct.

E  interleukin-1 activating the T helper cell

F  binding of T-cell to a class II MHC receptor on a macrophage

A  IgD

B  IgG

C  IgE

D  IgA

E  IgM

A  secrete antibodies

B  function in allergic reactions

C  directly destroy target cells

D  suppress immune reactions

E  activate B cells and other T cells

A  variable region

B  epitope

C  hapten

D  antigen binding site

E  None of the choices are correct.

A  aid in cellular development

B  are the result of genetic expression

C  function in recognition of self molecules

D  All of the choices are correct.

E  receive and transmit chemical messages among other cells of the system

A  have molecular complexity

B  are cells or large, complex molecules

C  are foreign to the immune system

D  are large molecules with a minimum molecular weight of 1,000

E  have large polymers made up of repeating subunits

A  autoantigens

B  superantigens

C  allergens

D  heterophilic antigens

E  None of the choices are correct.

A  delayed hypersensitivity T cells

B  natural killer (NK) cells

C  suppressor T cells

D  cytotoxic T cells

E  helper T cells

A  Cytotoxic T cells

B  B cells

C  Plasma cells

D  Antigen-presenting cells

E  Helper T cells

A  certain secreted complement components

B  self receptors recognized by T lymphocytes

C  all HLA antigens

D  receptors located primarily on macrophages and B cells

E  All of the choices are correct.

A  false

B  true

A  contains a central J chain

B  can serve as a B-cell receptor

C  is the first class synthesized by a plasma cell

D  is a dimer

E  has 10 antigen binding sites

A  bacterial toxins that activate T cells at a 100 times greater rate than other antigens

B  body tissues that the immune system mistakes as foreign

C  None of the choices are correct.

D  those that evoke allergic reactions

E  cell markers found in some member of a species but not in other members

A  true

B  false

A  IgE

B  IgG

C  IgM

D  IgA

E  IgD

A  develop into clones of B and T cells with extreme variations of specificity

B  have membrane receptors that recognize foreign antigens

C  gain tolerance to self by destruction of lymphocytes that could react against self

D  possess MHC antigens for recognizing self

E  All of the choices are correct.

A  All of the choices are correct.

B    

C  located in the thymus gland

D  found on the third chromosome

E  glycoproteins, called MHC antigens, found on all body cells

F  a set of genes that code for MHC glycoproteins

A  islet of Langerhans cells

B  epithelial cells

C  eosinophils

D  red blood cells

E  leukocytes

A  IgG only

B  IgD only

C  IgM and IgD

D  IgM only

E  IgD and IgE

A  Respiratory tract

B  Skin

C  Digestive tract

D  Urinary tract

E  Eyes

A  increases metabolism

B  increases the availability of iron

C  reduces the ability of temperature-sensitive organisms to multiply

D  increases phagocytosis

E  stimulates hematopoiesis

A  Includes chemicals such as lysozyme and lactic acid
Involves barriers at portals of entry
Examples include the ciliated epithelium of the respiratory passages, excretion of urine, and production of tears

B  Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

C  Includes chemicals such as lysozyme and lactic acid
Involves recognition of foreign agents by their pathogen-associated molecular patterns

D  Involves barriers at portals of entry
Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

A  monocytes

B  eosinophils

C  lymphocytes

D  basophils

E  neutrophils

A  macrophages

B  primary phagocytes

C  cytotoxic T cells

D  killer T cells

E  neutrophils

A  mast cells

B  eosinophils

C  platelets

D  macrophages

E  dendritic cells

A  Eosinophils

B  Neutrophils

C  Lymphocytes

D  Basophils

E  Monocytes

A  redness

B  chills

C  swelling

D  pain

E  warmth

A  antigens

B  antibodies

C  digestive enzymes

D  histamine

E  lysozyme

A  granulocytes

B  None of the choices are correct.

C  leukocytes

D  agranulocytes

E  monocytes

A  Destroy microbes

B  Cause a fever

C  Mobilize and attract immune components to injury site

D  Start tissue repair

E  Block further invasion

A  production of white blood cells, red blood cells, and platelets

B  migration of white blood cells from the blood out to the tissues

C  plugging of broken vessels to stop bleeding

D  loss of blood due to hemorrhaging

E  production of only red blood cells

A  tears

B  hairs

C  T cells

D  mucus

E  unbroken skin

A  All of the choices are correct.

B  contains albumin and globulins

C  is mostly water

D  contains fibrinogen

E  is the liquid portion of blood in which blood cells are suspended

A  Dolar—pain

B  Tumor—cancer

C  None of these are mismatched.

D  Rubor—redness

E  Calor—warmth

A  Pyrogens cause vasodilation and increased capillary permeability.

B  Serotonin causes smooth muscle contraction.

C  Fever could be beneficial to inhibiting the pathogen.

D  Basophils and mast cells release histamine.

E  It can last hours to years.

A  digestive tract

B  eyes

C  skin

D  urinary tract

E  respiratory tract

A  Intracellular fluid

B  Bloodstream

C  Lymphatic system

D  Extracellular fluid

A  B cells; neutrophils

B  B cells; T cells

C  Monocytes; basophils

D  Basophils; T cells

E  T cells; B cells

A  After birth, produced in red bone marrow sites

B  Develop from undifferentiated stem cells

C  Include erythrocytes that, when mature, lose their nuclei

D  Include Kupffer cells

E  Include leukocytes that are either granulocytes or agranulocytes

A  vasodilation

B  chemotaxis

C  phagocytosis

D  diapedesis

E  motility

A  thymus

B  tonsils

C  lymph nodes

D  GALT

E  spleen

A  Internal cellular and chemical defenses
Phagocytosis and inflammation
Anatomical and physiological barriers

B  Host defenses due to B and T cells and their products
Use of drugs and antibiotics
Anatomical and physiological barriers

C  Internal cellular and chemical defenses
Use of drugs and antibiotics
Host defenses due to B and T cells and their products

D  Host defenses due to B and T cells and their products
Use of drugs and antibiotics

A  physically restricts pathogens to a specific region

B  destroys pathogens

C  creates a physical barrier against pathogens

D  None of the choices are correct.

E  is toxic to pathogens