Lecture Exam 4 (Ch 12, 13, 14)

A  atopic

B  antibody mediated

C  T-cell mediated

D  delayed

E  systemic anaphylactic

A  fetal Rh + cells enter an Rh – mother

B  maternal Rh + cells enter an Rh -fetus

C  fetal Rh + cells enter an Rh + mother

D  maternal Rh ˗ cells enter an Rh + fetus

E  fetal Rh ˗ cells enter an Rh + mother

A  desensitization

B  immunodeficiency

C  autoimmune disease

D  hypersensitivity

E  transfusion reaction

A  immunopathology

B  histopathology

C  humoralpathology

D  hemopathology

E  epidemiology

A  IgE

B  foreign cells

C  IgM

D  IgG

E  complement

A  metastatic cancer

B  Graves’ disease

C  type I diabetes

D  rheumatic fever

E  systemic lupus erythematosus

A  hypograft

B  autograft

C  xenograft

D    

E  isograft

F  allograft

A  Ingestant

B  None of the choices are correct.

C  Injectant

D  Inhalant

E  Contactant

A  pruritus and headache

B  wheal and flare reaction in skin

C  constriction of smooth muscle of bronchi and the intestine

D  relaxes vascular smooth muscle

E  increased sensitivity to pain

A  type I only

B  type IV only

C  type I, type II, type III, and type IV

D  type I and type IV

E  type I, type II, and type III

A  IgE and mast cells

B  a transfusion reaction

C  autoantibodies and T cells

D  a deficiency in T-cell development

E  graft rejection

A  Contact dermatitis

B  Diarrhea

C  Rhinitis

D  Sneezing

E  Rashes

A  inhibit the activity of lymphocytes

B  relieve inflammatory symptoms

C  block synthesis of leukotrienes

D  reverse spasms of respiratory smooth muscles

E  bind to histamine receptors on target organs

A  Degranulation

B  Prostaglandins cause vasodilation and increased vascular permeability

C  Binding of IgE by the Fc region to mast cells and basophils

D  Histamine acts on smooth muscle

E  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

A  myelin sheath cells of the nervous system

B  acetylcholine receptors on smooth muscle

C  acetylcholine receptors on skeletal muscle

D  cells in thyroid follicles

E  sodium pump proteins in the cell membrane

A  Involves an immune complex reaction

B  The Arthus reaction is a local response

C  Serum sickness is a systemic response

D  Antigen-antibody complexes are deposited in the basement membrane of epithelial tissues

E  Involves production of IgG and IgE antibodies

A  eczema

B  anaphylaxis

C  allergic rhinitis

D  asthma

E  atopic dermatitis

A  Blood transfusion

B  Both skin graft and organ transplantation

C  Skin graft

D  All of thechoices are correct.

E  Organ transplantation

A  None of thechoices are correct.

B  degranulation

C  desensitization

D  sensitization

E  tissue matching

A  Prostaglandins cause vasodilation and increased vascular permeability

B  Histamine acts on smooth muscle

C  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

D  Binding of IgE by the Fc region to mast cells and basophils

E  Degranulation

A  Graft versus host disease

B  Formation of autoantibodies

C  Hypogammaglobulinemia

D  None of the choices are correct.

E  Host rejection of graft

A  Anaphylaxis

B  Both anaphylaxis and antibody mediated

C  Immune complex mediated

D  Antibody mediated

E  Both antibody mediated and immune complex mediated

A  rheumatoid arthritis

B  myasthenia gravis

C  tuberculin reaction

D  Graves’ disease

E  multiple sclerosis

A  leukotriene

B  serotonin

C  platelet-activating factor

D  prostaglandin

E  histamine

A  four antigen binding sites

B  a variable and constant region on each polypeptide chain

C  two identical light polypeptide chains

D  two identical heavy polypeptide chains

E  disulfide bonds between polypeptide chains

A  hormonal signals that initiate development

B  T cells maturing in the thymus

C  All of the choices are correct.

D  B cells maturing in bone marrow sites

E  release of mature lymphocytes to begin migration to various lymphoid organs

A  Fc

B  Fab

C  hinge

D  terminal

E  variable

A  secrete antibodies

B  function in allergic reactions

C  suppress immune reactions

D  directly destroy target cells

E  activate B cells and other T cells

A  include dendritic cells

B  engulf and modify antigen to be more immunogenic

C  include macrophages

D  All of the choices are correct.

E  hold and present processed antigen on their cell membrane surface

A  false

B  true

A  typically a protein antigen

B  binding of T-cell to a site on the antigen

C  binding of T-cell to a class II MHC receptor on a macrophage

D  All of the choices are correct.

E  interleukin-1 activating the T helper cell

F    

A  IgM

B  IgA

C  IgD

D  IgG

E  IgE

A  suppress immune reactions

B  activate B cells and other T cells

C  function in allergic reactions

D  secrete antibodies

E  directly destroy target cells

A  None of the choices are correct.

B  antigen binding site

C  epitope

D  variable region

E  hapten

A  All of the choices are correct.

B  are the result of genetic expression

C  aid in cellular development

D  receive and transmit chemical messages among other cells of the system

E  function in recognition of self molecules

A  have molecular complexity

B  are cells or large, complex molecules

C  are foreign to the immune system

D  have large polymers made up of repeating subunits

E  are large molecules with a minimum molecular weight of 1,000

A  heterophilic antigens

B  superantigens

C  allergens

D  None of the choices are correct.

E  autoantigens

A  suppressor T cells

B  delayed hypersensitivity T cells

C  helper T cells

D  cytotoxic T cells

E  natural killer (NK) cells

A  Cytotoxic T cells

B  Antigen-presenting cells

C  B cells

D  Helper T cells

E  Plasma cells

A  receptors located primarily on macrophages and B cells

B  certain secreted complement components

C  All of the choices are correct.

D  self receptors recognized by T lymphocytes

E  all HLA antigens

A  true

B  false

A  contains a central J chain

B  is a dimer

C  is the first class synthesized by a plasma cell

D  has 10 antigen binding sites

E  can serve as a B-cell receptor

A  body tissues that the immune system mistakes as foreign

B  bacterial toxins that activate T cells at a 100 times greater rate than other antigens

C  those that evoke allergic reactions

D  cell markers found in some member of a species but not in other members

E  None of the choices are correct.

A  true

B  false

A  IgG

B  IgE

C  IgD

D  IgA

E  IgM

A  have membrane receptors that recognize foreign antigens

B  possess MHC antigens for recognizing self

C  gain tolerance to self by destruction of lymphocytes that could react against self

D  All of the choices are correct.

E  develop into clones of B and T cells with extreme variations of specificity

A  glycoproteins, called MHC antigens, found on all body cells

B    

C  found on the third chromosome

D  All of the choices are correct.

E  a set of genes that code for MHC glycoproteins

F  located in the thymus gland

A  leukocytes

B  islet of Langerhans cells

C  epithelial cells

D  red blood cells

E  eosinophils

A  IgG only

B  IgD and IgE

C  IgD only

D  IgM only

E  IgM and IgD

A  Skin

B  Digestive tract

C  Eyes

D  Respiratory tract

E  Urinary tract

A  reduces the ability of temperature-sensitive organisms to multiply

B  increases metabolism

C  stimulates hematopoiesis

D  increases phagocytosis

E  increases the availability of iron

A  Involves barriers at portals of entry
Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

B  Includes chemicals such as lysozyme and lactic acid
Involves recognition of foreign agents by their pathogen-associated molecular patterns

C  Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

D  Includes chemicals such as lysozyme and lactic acid
Involves barriers at portals of entry
Examples include the ciliated epithelium of the respiratory passages, excretion of urine, and production of tears

A  eosinophils

B  neutrophils

C  basophils

D  lymphocytes

E  monocytes

A  macrophages

B  primary phagocytes

C  cytotoxic T cells

D  neutrophils

E  killer T cells

A  dendritic cells

B  eosinophils

C  mast cells

D  macrophages

E  platelets

A  Basophils

B  Eosinophils

C  Monocytes

D  Neutrophils

E  Lymphocytes

A  chills

B  redness

C  swelling

D  warmth

E  pain

A  histamine

B  digestive enzymes

C  lysozyme

D  antibodies

E  antigens

A  leukocytes

B  granulocytes

C  None of the choices are correct.

D  monocytes

E  agranulocytes

A  Cause a fever

B  Mobilize and attract immune components to injury site

C  Start tissue repair

D  Destroy microbes

E  Block further invasion

A  migration of white blood cells from the blood out to the tissues

B  plugging of broken vessels to stop bleeding

C  loss of blood due to hemorrhaging

D  production of white blood cells, red blood cells, and platelets

E  production of only red blood cells

A  tears

B  hairs

C  mucus

D  unbroken skin

E  T cells

A  is mostly water

B  is the liquid portion of blood in which blood cells are suspended

C  All of the choices are correct.

D  contains albumin and globulins

E  contains fibrinogen

A  Calor—warmth

B  Rubor—redness

C  Tumor—cancer

D  Dolar—pain

E  None of these are mismatched.

A  Fever could be beneficial to inhibiting the pathogen.

B  Serotonin causes smooth muscle contraction.

C  It can last hours to years.

D  Pyrogens cause vasodilation and increased capillary permeability.

E  Basophils and mast cells release histamine.

A  urinary tract

B  digestive tract

C  skin

D  respiratory tract

E  eyes

A  Intracellular fluid

B  Extracellular fluid

C  Bloodstream

D  Lymphatic system

A  T cells; B cells

B  Basophils; T cells

C  B cells; neutrophils

D  Monocytes; basophils

E  B cells; T cells

A  Develop from undifferentiated stem cells

B  Include Kupffer cells

C  Include leukocytes that are either granulocytes or agranulocytes

D  After birth, produced in red bone marrow sites

E  Include erythrocytes that, when mature, lose their nuclei

A  chemotaxis

B  vasodilation

C  diapedesis

D  motility

E  phagocytosis

A  GALT

B  lymph nodes

C  tonsils

D  spleen

E  thymus

A  Host defenses due to B and T cells and their products
Use of drugs and antibiotics

B  Internal cellular and chemical defenses
Phagocytosis and inflammation
Anatomical and physiological barriers

C  Internal cellular and chemical defenses
Use of drugs and antibiotics
Host defenses due to B and T cells and their products

D  Host defenses due to B and T cells and their products
Use of drugs and antibiotics
Anatomical and physiological barriers

A  None of the choices are correct.

B  creates a physical barrier against pathogens

C  physically restricts pathogens to a specific region

D  is toxic to pathogens

E  destroys pathogens