Lecture Exam 4 (Ch 12, 13, 14)

A  atopic

B  systemic anaphylactic

C  T-cell mediated

D  delayed

E  antibody mediated

A  maternal Rh + cells enter an Rh -fetus

B  fetal Rh + cells enter an Rh + mother

C  fetal Rh ˗ cells enter an Rh + mother

D  fetal Rh + cells enter an Rh – mother

E  maternal Rh ˗ cells enter an Rh + fetus

A  autoimmune disease

B  immunodeficiency

C  hypersensitivity

D  transfusion reaction

E  desensitization

A  immunopathology

B  humoralpathology

C  histopathology

D  hemopathology

E  epidemiology

A  foreign cells

B  IgE

C  IgM

D  IgG

E  complement

A  systemic lupus erythematosus

B  metastatic cancer

C  type I diabetes

D  rheumatic fever

E  Graves’ disease

A  xenograft

B  hypograft

C  isograft

D  autograft

E  allograft

F    

A  Injectant

B  Inhalant

C  Ingestant

D  None of the choices are correct.

E  Contactant

A  relaxes vascular smooth muscle

B  constriction of smooth muscle of bronchi and the intestine

C  increased sensitivity to pain

D  pruritus and headache

E  wheal and flare reaction in skin

A  type IV only

B  type I and type IV

C  type I, type II, and type III

D  type I, type II, type III, and type IV

E  type I only

A  a deficiency in T-cell development

B  autoantibodies and T cells

C  a transfusion reaction

D  IgE and mast cells

E  graft rejection

A  Rashes

B  Sneezing

C  Contact dermatitis

D  Diarrhea

E  Rhinitis

A  inhibit the activity of lymphocytes

B  relieve inflammatory symptoms

C  bind to histamine receptors on target organs

D  reverse spasms of respiratory smooth muscles

E  block synthesis of leukotrienes

A  Binding of IgE by the Fc region to mast cells and basophils

B  Histamine acts on smooth muscle

C  Degranulation

D  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

E  Prostaglandins cause vasodilation and increased vascular permeability

A  acetylcholine receptors on skeletal muscle

B  acetylcholine receptors on smooth muscle

C  sodium pump proteins in the cell membrane

D  cells in thyroid follicles

E  myelin sheath cells of the nervous system

A  Antigen-antibody complexes are deposited in the basement membrane of epithelial tissues

B  The Arthus reaction is a local response

C  Serum sickness is a systemic response

D  Involves an immune complex reaction

E  Involves production of IgG and IgE antibodies

A  asthma

B  atopic dermatitis

C  allergic rhinitis

D  anaphylaxis

E  eczema

A  Skin graft

B  Blood transfusion

C  Organ transplantation

D  Both skin graft and organ transplantation

E  All of thechoices are correct.

A  degranulation

B  desensitization

C  tissue matching

D  sensitization

E  None of thechoices are correct.

A  Degranulation

B  Histamine acts on smooth muscle

C  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

D  Binding of IgE by the Fc region to mast cells and basophils

E  Prostaglandins cause vasodilation and increased vascular permeability

A  Hypogammaglobulinemia

B  Host rejection of graft

C  None of the choices are correct.

D  Formation of autoantibodies

E  Graft versus host disease

A  Both antibody mediated and immune complex mediated

B  Antibody mediated

C  Both anaphylaxis and antibody mediated

D  Immune complex mediated

E  Anaphylaxis

A  myasthenia gravis

B  Graves’ disease

C  rheumatoid arthritis

D  tuberculin reaction

E  multiple sclerosis

A  leukotriene

B  histamine

C  platelet-activating factor

D  prostaglandin

E  serotonin

A  two identical light polypeptide chains

B  four antigen binding sites

C  a variable and constant region on each polypeptide chain

D  disulfide bonds between polypeptide chains

E  two identical heavy polypeptide chains

A  hormonal signals that initiate development

B  B cells maturing in bone marrow sites

C  release of mature lymphocytes to begin migration to various lymphoid organs

D  T cells maturing in the thymus

E  All of the choices are correct.

A  Fab

B  Fc

C  terminal

D  variable

E  hinge

A  directly destroy target cells

B  function in allergic reactions

C  activate B cells and other T cells

D  secrete antibodies

E  suppress immune reactions

A  hold and present processed antigen on their cell membrane surface

B  All of the choices are correct.

C  include dendritic cells

D  include macrophages

E  engulf and modify antigen to be more immunogenic

A  true

B  false

A  interleukin-1 activating the T helper cell

B  typically a protein antigen

C    

D  binding of T-cell to a class II MHC receptor on a macrophage

E  All of the choices are correct.

F  binding of T-cell to a site on the antigen

A  IgG

B  IgE

C  IgD

D  IgA

E  IgM

A  suppress immune reactions

B  activate B cells and other T cells

C  function in allergic reactions

D  directly destroy target cells

E  secrete antibodies

A  None of the choices are correct.

B  variable region

C  antigen binding site

D  epitope

E  hapten

A  All of the choices are correct.

B  receive and transmit chemical messages among other cells of the system

C  aid in cellular development

D  function in recognition of self molecules

E  are the result of genetic expression

A  are cells or large, complex molecules

B  are foreign to the immune system

C  have large polymers made up of repeating subunits

D  are large molecules with a minimum molecular weight of 1,000

E  have molecular complexity

A  superantigens

B  autoantigens

C  allergens

D  None of the choices are correct.

E  heterophilic antigens

A  delayed hypersensitivity T cells

B  cytotoxic T cells

C  suppressor T cells

D  helper T cells

E  natural killer (NK) cells

A  Helper T cells

B  Antigen-presenting cells

C  B cells

D  Cytotoxic T cells

E  Plasma cells

A  receptors located primarily on macrophages and B cells

B  certain secreted complement components

C  self receptors recognized by T lymphocytes

D  all HLA antigens

E  All of the choices are correct.

A  true

B  false

A  is the first class synthesized by a plasma cell

B  contains a central J chain

C  has 10 antigen binding sites

D  can serve as a B-cell receptor

E  is a dimer

A  None of the choices are correct.

B  cell markers found in some member of a species but not in other members

C  body tissues that the immune system mistakes as foreign

D  bacterial toxins that activate T cells at a 100 times greater rate than other antigens

E  those that evoke allergic reactions

A  false

B  true

A  IgG

B  IgA

C  IgE

D  IgD

E  IgM

A  possess MHC antigens for recognizing self

B  All of the choices are correct.

C  gain tolerance to self by destruction of lymphocytes that could react against self

D  have membrane receptors that recognize foreign antigens

E  develop into clones of B and T cells with extreme variations of specificity

A  a set of genes that code for MHC glycoproteins

B    

C  located in the thymus gland

D  found on the third chromosome

E  All of the choices are correct.

F  glycoproteins, called MHC antigens, found on all body cells

A  leukocytes

B  epithelial cells

C  red blood cells

D  islet of Langerhans cells

E  eosinophils

A  IgM only

B  IgD only

C  IgD and IgE

D  IgG only

E  IgM and IgD

A  Skin

B  Digestive tract

C  Eyes

D  Respiratory tract

E  Urinary tract

A  increases the availability of iron

B  increases metabolism

C  stimulates hematopoiesis

D  increases phagocytosis

E  reduces the ability of temperature-sensitive organisms to multiply

A  Involves barriers at portals of entry
Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

B  Includes chemicals such as lysozyme and lactic acid
Involves recognition of foreign agents by their pathogen-associated molecular patterns

C  Includes chemicals such as lysozyme and lactic acid
Involves barriers at portals of entry
Examples include the ciliated epithelium of the respiratory passages, excretion of urine, and production of tears

D  Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

A  monocytes

B  eosinophils

C  basophils

D  neutrophils

E  lymphocytes

A  cytotoxic T cells

B  neutrophils

C  killer T cells

D  macrophages

E  primary phagocytes

A  eosinophils

B  mast cells

C  macrophages

D  dendritic cells

E  platelets

A  Eosinophils

B  Basophils

C  Lymphocytes

D  Neutrophils

E  Monocytes

A  swelling

B  chills

C  pain

D  redness

E  warmth

A  antigens

B  digestive enzymes

C  lysozyme

D  histamine

E  antibodies

A  leukocytes

B  granulocytes

C  agranulocytes

D  monocytes

E  None of the choices are correct.

A  Cause a fever

B  Mobilize and attract immune components to injury site

C  Destroy microbes

D  Block further invasion

E  Start tissue repair

A  plugging of broken vessels to stop bleeding

B  production of white blood cells, red blood cells, and platelets

C  migration of white blood cells from the blood out to the tissues

D  loss of blood due to hemorrhaging

E  production of only red blood cells

A  tears

B  unbroken skin

C  hairs

D  T cells

E  mucus

A  is the liquid portion of blood in which blood cells are suspended

B  contains albumin and globulins

C  contains fibrinogen

D  is mostly water

E  All of the choices are correct.

A  None of these are mismatched.

B  Rubor—redness

C  Dolar—pain

D  Tumor—cancer

E  Calor—warmth

A  Basophils and mast cells release histamine.

B  It can last hours to years.

C  Fever could be beneficial to inhibiting the pathogen.

D  Serotonin causes smooth muscle contraction.

E  Pyrogens cause vasodilation and increased capillary permeability.

A  urinary tract

B  eyes

C  skin

D  digestive tract

E  respiratory tract

A  Intracellular fluid

B  Extracellular fluid

C  Bloodstream

D  Lymphatic system

A  B cells; neutrophils

B  T cells; B cells

C  Monocytes; basophils

D  B cells; T cells

E  Basophils; T cells

A  Include Kupffer cells

B  Include erythrocytes that, when mature, lose their nuclei

C  After birth, produced in red bone marrow sites

D  Include leukocytes that are either granulocytes or agranulocytes

E  Develop from undifferentiated stem cells

A  motility

B  vasodilation

C  diapedesis

D  chemotaxis

E  phagocytosis

A  tonsils

B  spleen

C  thymus

D  lymph nodes

E  GALT

A  Internal cellular and chemical defenses
Use of drugs and antibiotics
Host defenses due to B and T cells and their products

B  Host defenses due to B and T cells and their products
Use of drugs and antibiotics

C  Internal cellular and chemical defenses
Phagocytosis and inflammation
Anatomical and physiological barriers

D  Host defenses due to B and T cells and their products
Use of drugs and antibiotics
Anatomical and physiological barriers

A  None of the choices are correct.

B  destroys pathogens

C  physically restricts pathogens to a specific region

D  creates a physical barrier against pathogens

E  is toxic to pathogens