Lecture Exam 4 (Ch 12, 13, 14)

A  atopic

B  systemic anaphylactic

C  delayed

D  antibody mediated

E  T-cell mediated

A  fetal Rh + cells enter an Rh – mother

B  fetal Rh + cells enter an Rh + mother

C  maternal Rh ˗ cells enter an Rh + fetus

D  fetal Rh ˗ cells enter an Rh + mother

E  maternal Rh + cells enter an Rh -fetus

A  autoimmune disease

B  immunodeficiency

C  desensitization

D  hypersensitivity

E  transfusion reaction

A  epidemiology

B  humoralpathology

C  histopathology

D  immunopathology

E  hemopathology

A  IgE

B  foreign cells

C  IgG

D  complement

E  IgM

A  metastatic cancer

B  Graves’ disease

C  type I diabetes

D  rheumatic fever

E  systemic lupus erythematosus

A  autograft

B  isograft

C    

D  xenograft

E  allograft

F  hypograft

A  None of the choices are correct.

B  Ingestant

C  Injectant

D  Contactant

E  Inhalant

A  relaxes vascular smooth muscle

B  constriction of smooth muscle of bronchi and the intestine

C  wheal and flare reaction in skin

D  increased sensitivity to pain

E  pruritus and headache

A  type IV only

B  type I and type IV

C  type I, type II, and type III

D  type I, type II, type III, and type IV

E  type I only

A  IgE and mast cells

B  autoantibodies and T cells

C  graft rejection

D  a transfusion reaction

E  a deficiency in T-cell development

A  Diarrhea

B  Rhinitis

C  Sneezing

D  Rashes

E  Contact dermatitis

A  relieve inflammatory symptoms

B  inhibit the activity of lymphocytes

C  bind to histamine receptors on target organs

D  block synthesis of leukotrienes

E  reverse spasms of respiratory smooth muscles

A  Binding of IgE by the Fc region to mast cells and basophils

B  Prostaglandins cause vasodilation and increased vascular permeability

C  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

D  Degranulation

E  Histamine acts on smooth muscle

A  acetylcholine receptors on smooth muscle

B  acetylcholine receptors on skeletal muscle

C  cells in thyroid follicles

D  myelin sheath cells of the nervous system

E  sodium pump proteins in the cell membrane

A  Serum sickness is a systemic response

B  Antigen-antibody complexes are deposited in the basement membrane of epithelial tissues

C  Involves an immune complex reaction

D  The Arthus reaction is a local response

E  Involves production of IgG and IgE antibodies

A  eczema

B  asthma

C  atopic dermatitis

D  allergic rhinitis

E  anaphylaxis

A  Skin graft

B  Blood transfusion

C  All of thechoices are correct.

D  Both skin graft and organ transplantation

E  Organ transplantation

A  degranulation

B  tissue matching

C  desensitization

D  None of thechoices are correct.

E  sensitization

A  Histamine acts on smooth muscle

B  Binding of IgE by the Fc region to mast cells and basophils

C  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

D  Prostaglandins cause vasodilation and increased vascular permeability

E  Degranulation

A  Hypogammaglobulinemia

B  None of the choices are correct.

C  Formation of autoantibodies

D  Host rejection of graft

E  Graft versus host disease

A  Anaphylaxis

B  Both antibody mediated and immune complex mediated

C  Immune complex mediated

D  Both anaphylaxis and antibody mediated

E  Antibody mediated

A  myasthenia gravis

B  multiple sclerosis

C  tuberculin reaction

D  Graves’ disease

E  rheumatoid arthritis

A  histamine

B  platelet-activating factor

C  leukotriene

D  prostaglandin

E  serotonin

A  four antigen binding sites

B  two identical heavy polypeptide chains

C  two identical light polypeptide chains

D  disulfide bonds between polypeptide chains

E  a variable and constant region on each polypeptide chain

A  B cells maturing in bone marrow sites

B  hormonal signals that initiate development

C  T cells maturing in the thymus

D  All of the choices are correct.

E  release of mature lymphocytes to begin migration to various lymphoid organs

A  hinge

B  variable

C  Fab

D  Fc

E  terminal

A  directly destroy target cells

B  secrete antibodies

C  activate B cells and other T cells

D  function in allergic reactions

E  suppress immune reactions

A  include dendritic cells

B  include macrophages

C  All of the choices are correct.

D  engulf and modify antigen to be more immunogenic

E  hold and present processed antigen on their cell membrane surface

A  true

B  false

A  typically a protein antigen

B    

C  All of the choices are correct.

D  binding of T-cell to a class II MHC receptor on a macrophage

E  binding of T-cell to a site on the antigen

F  interleukin-1 activating the T helper cell

A  IgG

B  IgE

C  IgD

D  IgA

E  IgM

A  activate B cells and other T cells

B  function in allergic reactions

C  suppress immune reactions

D  directly destroy target cells

E  secrete antibodies

A  hapten

B  epitope

C  variable region

D  antigen binding site

E  None of the choices are correct.

A  function in recognition of self molecules

B  All of the choices are correct.

C  are the result of genetic expression

D  receive and transmit chemical messages among other cells of the system

E  aid in cellular development

A  are foreign to the immune system

B  have molecular complexity

C  have large polymers made up of repeating subunits

D  are cells or large, complex molecules

E  are large molecules with a minimum molecular weight of 1,000

A  heterophilic antigens

B  allergens

C  autoantigens

D  None of the choices are correct.

E  superantigens

A  delayed hypersensitivity T cells

B  helper T cells

C  cytotoxic T cells

D  suppressor T cells

E  natural killer (NK) cells

A  B cells

B  Antigen-presenting cells

C  Cytotoxic T cells

D  Plasma cells

E  Helper T cells

A  all HLA antigens

B  All of the choices are correct.

C  receptors located primarily on macrophages and B cells

D  certain secreted complement components

E  self receptors recognized by T lymphocytes

A  true

B  false

A  has 10 antigen binding sites

B  is the first class synthesized by a plasma cell

C  contains a central J chain

D  is a dimer

E  can serve as a B-cell receptor

A  None of the choices are correct.

B  cell markers found in some member of a species but not in other members

C  bacterial toxins that activate T cells at a 100 times greater rate than other antigens

D  body tissues that the immune system mistakes as foreign

E  those that evoke allergic reactions

A  false

B  true

A  IgG

B  IgE

C  IgA

D  IgM

E  IgD

A  gain tolerance to self by destruction of lymphocytes that could react against self

B  develop into clones of B and T cells with extreme variations of specificity

C  have membrane receptors that recognize foreign antigens

D  All of the choices are correct.

E  possess MHC antigens for recognizing self

A  located in the thymus gland

B  All of the choices are correct.

C  found on the third chromosome

D  a set of genes that code for MHC glycoproteins

E    

F  glycoproteins, called MHC antigens, found on all body cells

A  red blood cells

B  islet of Langerhans cells

C  eosinophils

D  epithelial cells

E  leukocytes

A  IgD only

B  IgG only

C  IgM only

D  IgD and IgE

E  IgM and IgD

A  Respiratory tract

B  Digestive tract

C  Skin

D  Urinary tract

E  Eyes

A  stimulates hematopoiesis

B  increases phagocytosis

C  reduces the ability of temperature-sensitive organisms to multiply

D  increases metabolism

E  increases the availability of iron

A  Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

B  Includes chemicals such as lysozyme and lactic acid
Involves barriers at portals of entry
Examples include the ciliated epithelium of the respiratory passages, excretion of urine, and production of tears

C  Includes chemicals such as lysozyme and lactic acid
Involves recognition of foreign agents by their pathogen-associated molecular patterns

D  Involves barriers at portals of entry
Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

A  basophils

B  lymphocytes

C  neutrophils

D  monocytes

E  eosinophils

A  macrophages

B  cytotoxic T cells

C  killer T cells

D  neutrophils

E  primary phagocytes

A  eosinophils

B  macrophages

C  mast cells

D  platelets

E  dendritic cells

A  Monocytes

B  Lymphocytes

C  Basophils

D  Eosinophils

E  Neutrophils

A  pain

B  chills

C  swelling

D  warmth

E  redness

A  digestive enzymes

B  lysozyme

C  antigens

D  histamine

E  antibodies

A  leukocytes

B  agranulocytes

C  None of the choices are correct.

D  granulocytes

E  monocytes

A  Destroy microbes

B  Block further invasion

C  Cause a fever

D  Start tissue repair

E  Mobilize and attract immune components to injury site

A  plugging of broken vessels to stop bleeding

B  production of white blood cells, red blood cells, and platelets

C  loss of blood due to hemorrhaging

D  migration of white blood cells from the blood out to the tissues

E  production of only red blood cells

A  mucus

B  unbroken skin

C  hairs

D  T cells

E  tears

A  contains albumin and globulins

B  contains fibrinogen

C  is mostly water

D  is the liquid portion of blood in which blood cells are suspended

E  All of the choices are correct.

A  Tumor—cancer

B  Calor—warmth

C  Rubor—redness

D  Dolar—pain

E  None of these are mismatched.

A  Fever could be beneficial to inhibiting the pathogen.

B  Pyrogens cause vasodilation and increased capillary permeability.

C  It can last hours to years.

D  Basophils and mast cells release histamine.

E  Serotonin causes smooth muscle contraction.

A  respiratory tract

B  eyes

C  urinary tract

D  skin

E  digestive tract

A  Extracellular fluid

B  Intracellular fluid

C  Bloodstream

D  Lymphatic system

A  B cells; neutrophils

B  Monocytes; basophils

C  T cells; B cells

D  B cells; T cells

E  Basophils; T cells

A  Include erythrocytes that, when mature, lose their nuclei

B  After birth, produced in red bone marrow sites

C  Develop from undifferentiated stem cells

D  Include leukocytes that are either granulocytes or agranulocytes

E  Include Kupffer cells

A  vasodilation

B  chemotaxis

C  phagocytosis

D  motility

E  diapedesis

A  lymph nodes

B  spleen

C  GALT

D  tonsils

E  thymus

A  Host defenses due to B and T cells and their products
Use of drugs and antibiotics

B  Internal cellular and chemical defenses
Use of drugs and antibiotics
Host defenses due to B and T cells and their products

C  Host defenses due to B and T cells and their products
Use of drugs and antibiotics
Anatomical and physiological barriers

D  Internal cellular and chemical defenses
Phagocytosis and inflammation
Anatomical and physiological barriers

A  is toxic to pathogens

B  physically restricts pathogens to a specific region

C  creates a physical barrier against pathogens

D  destroys pathogens

E  None of the choices are correct.