Lecture Exam 4 (Ch 12, 13, 14)

A  systemic anaphylactic

B  delayed

C  atopic

D  antibody mediated

E  T-cell mediated

A  maternal Rh + cells enter an Rh -fetus

B  fetal Rh + cells enter an Rh + mother

C  maternal Rh ˗ cells enter an Rh + fetus

D  fetal Rh + cells enter an Rh – mother

E  fetal Rh ˗ cells enter an Rh + mother

A  autoimmune disease

B  transfusion reaction

C  hypersensitivity

D  desensitization

E  immunodeficiency

A  epidemiology

B  immunopathology

C  humoralpathology

D  histopathology

E  hemopathology

A  complement

B  foreign cells

C  IgE

D  IgM

E  IgG

A  Graves’ disease

B  metastatic cancer

C  systemic lupus erythematosus

D  type I diabetes

E  rheumatic fever

A  isograft

B  allograft

C  hypograft

D  autograft

E    

F  xenograft

A  None of the choices are correct.

B  Injectant

C  Inhalant

D  Ingestant

E  Contactant

A  pruritus and headache

B  wheal and flare reaction in skin

C  relaxes vascular smooth muscle

D  constriction of smooth muscle of bronchi and the intestine

E  increased sensitivity to pain

A  type I only

B  type IV only

C  type I, type II, type III, and type IV

D  type I, type II, and type III

E  type I and type IV

A  a deficiency in T-cell development

B  autoantibodies and T cells

C  a transfusion reaction

D  IgE and mast cells

E  graft rejection

A  Rashes

B  Contact dermatitis

C  Diarrhea

D  Rhinitis

E  Sneezing

A  inhibit the activity of lymphocytes

B  reverse spasms of respiratory smooth muscles

C  bind to histamine receptors on target organs

D  block synthesis of leukotrienes

E  relieve inflammatory symptoms

A  Degranulation

B  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

C  Histamine acts on smooth muscle

D  Prostaglandins cause vasodilation and increased vascular permeability

E  Binding of IgE by the Fc region to mast cells and basophils

A  acetylcholine receptors on skeletal muscle

B  acetylcholine receptors on smooth muscle

C  sodium pump proteins in the cell membrane

D  myelin sheath cells of the nervous system

E  cells in thyroid follicles

A  Involves production of IgG and IgE antibodies

B  Serum sickness is a systemic response

C  Involves an immune complex reaction

D  The Arthus reaction is a local response

E  Antigen-antibody complexes are deposited in the basement membrane of epithelial tissues

A  allergic rhinitis

B  asthma

C  anaphylaxis

D  atopic dermatitis

E  eczema

A  Skin graft

B  Both skin graft and organ transplantation

C  All of thechoices are correct.

D  Organ transplantation

E  Blood transfusion

A  degranulation

B  None of thechoices are correct.

C  tissue matching

D  sensitization

E  desensitization

A  Degranulation

B  Binding of IgE by the Fc region to mast cells and basophils

C  Prostaglandins cause vasodilation and increased vascular permeability

D  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

E  Histamine acts on smooth muscle

A  Hypogammaglobulinemia

B  None of the choices are correct.

C  Host rejection of graft

D  Graft versus host disease

E  Formation of autoantibodies

A  Immune complex mediated

B  Both anaphylaxis and antibody mediated

C  Anaphylaxis

D  Both antibody mediated and immune complex mediated

E  Antibody mediated

A  rheumatoid arthritis

B  tuberculin reaction

C  myasthenia gravis

D  Graves’ disease

E  multiple sclerosis

A  prostaglandin

B  serotonin

C  histamine

D  platelet-activating factor

E  leukotriene

A  two identical light polypeptide chains

B  two identical heavy polypeptide chains

C  disulfide bonds between polypeptide chains

D  a variable and constant region on each polypeptide chain

E  four antigen binding sites

A  All of the choices are correct.

B  B cells maturing in bone marrow sites

C  hormonal signals that initiate development

D  release of mature lymphocytes to begin migration to various lymphoid organs

E  T cells maturing in the thymus

A  variable

B  terminal

C  Fab

D  Fc

E  hinge

A  activate B cells and other T cells

B  secrete antibodies

C  function in allergic reactions

D  directly destroy target cells

E  suppress immune reactions

A  include macrophages

B  engulf and modify antigen to be more immunogenic

C  include dendritic cells

D  All of the choices are correct.

E  hold and present processed antigen on their cell membrane surface

A  false

B  true

A  interleukin-1 activating the T helper cell

B  All of the choices are correct.

C  typically a protein antigen

D  binding of T-cell to a class II MHC receptor on a macrophage

E  binding of T-cell to a site on the antigen

F    

A  IgM

B  IgD

C  IgE

D  IgA

E  IgG

A  activate B cells and other T cells

B  secrete antibodies

C  suppress immune reactions

D  function in allergic reactions

E  directly destroy target cells

A  antigen binding site

B  None of the choices are correct.

C  hapten

D  variable region

E  epitope

A  aid in cellular development

B  All of the choices are correct.

C  function in recognition of self molecules

D  receive and transmit chemical messages among other cells of the system

E  are the result of genetic expression

A  are cells or large, complex molecules

B  have large polymers made up of repeating subunits

C  have molecular complexity

D  are foreign to the immune system

E  are large molecules with a minimum molecular weight of 1,000

A  superantigens

B  heterophilic antigens

C  allergens

D  None of the choices are correct.

E  autoantigens

A  helper T cells

B  delayed hypersensitivity T cells

C  natural killer (NK) cells

D  suppressor T cells

E  cytotoxic T cells

A  Antigen-presenting cells

B  Plasma cells

C  Cytotoxic T cells

D  Helper T cells

E  B cells

A  receptors located primarily on macrophages and B cells

B  All of the choices are correct.

C  self receptors recognized by T lymphocytes

D  all HLA antigens

E  certain secreted complement components

A  false

B  true

A  contains a central J chain

B  is a dimer

C  is the first class synthesized by a plasma cell

D  can serve as a B-cell receptor

E  has 10 antigen binding sites

A  those that evoke allergic reactions

B  cell markers found in some member of a species but not in other members

C  bacterial toxins that activate T cells at a 100 times greater rate than other antigens

D  None of the choices are correct.

E  body tissues that the immune system mistakes as foreign

A  false

B  true

A  IgM

B  IgG

C  IgD

D  IgA

E  IgE

A  gain tolerance to self by destruction of lymphocytes that could react against self

B  possess MHC antigens for recognizing self

C  have membrane receptors that recognize foreign antigens

D  All of the choices are correct.

E  develop into clones of B and T cells with extreme variations of specificity

A  All of the choices are correct.

B  glycoproteins, called MHC antigens, found on all body cells

C  a set of genes that code for MHC glycoproteins

D  found on the third chromosome

E  located in the thymus gland

F    

A  eosinophils

B  epithelial cells

C  islet of Langerhans cells

D  red blood cells

E  leukocytes

A  IgG only

B  IgM and IgD

C  IgD only

D  IgM only

E  IgD and IgE

A  Eyes

B  Urinary tract

C  Respiratory tract

D  Digestive tract

E  Skin

A  increases metabolism

B  increases phagocytosis

C  increases the availability of iron

D  reduces the ability of temperature-sensitive organisms to multiply

E  stimulates hematopoiesis

A  Includes chemicals such as lysozyme and lactic acid
Involves recognition of foreign agents by their pathogen-associated molecular patterns

B  Involves barriers at portals of entry
Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

C  Includes chemicals such as lysozyme and lactic acid
Involves barriers at portals of entry
Examples include the ciliated epithelium of the respiratory passages, excretion of urine, and production of tears

D  Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

A  monocytes

B  basophils

C  eosinophils

D  lymphocytes

E  neutrophils

A  cytotoxic T cells

B  neutrophils

C  killer T cells

D  macrophages

E  primary phagocytes

A  mast cells

B  platelets

C  macrophages

D  dendritic cells

E  eosinophils

A  Lymphocytes

B  Eosinophils

C  Monocytes

D  Basophils

E  Neutrophils

A  redness

B  swelling

C  chills

D  pain

E  warmth

A  lysozyme

B  histamine

C  digestive enzymes

D  antigens

E  antibodies

A  None of the choices are correct.

B  monocytes

C  granulocytes

D  agranulocytes

E  leukocytes

A  Start tissue repair

B  Destroy microbes

C  Mobilize and attract immune components to injury site

D  Block further invasion

E  Cause a fever

A  production of only red blood cells

B  plugging of broken vessels to stop bleeding

C  production of white blood cells, red blood cells, and platelets

D  migration of white blood cells from the blood out to the tissues

E  loss of blood due to hemorrhaging

A  T cells

B  mucus

C  hairs

D  unbroken skin

E  tears

A  contains fibrinogen

B  All of the choices are correct.

C  contains albumin and globulins

D  is mostly water

E  is the liquid portion of blood in which blood cells are suspended

A  Calor—warmth

B  Dolar—pain

C  None of these are mismatched.

D  Tumor—cancer

E  Rubor—redness

A  It can last hours to years.

B  Pyrogens cause vasodilation and increased capillary permeability.

C  Basophils and mast cells release histamine.

D  Fever could be beneficial to inhibiting the pathogen.

E  Serotonin causes smooth muscle contraction.

A  urinary tract

B  respiratory tract

C  skin

D  eyes

E  digestive tract

A  Intracellular fluid

B  Lymphatic system

C  Extracellular fluid

D  Bloodstream

A  B cells; T cells

B  B cells; neutrophils

C  Basophils; T cells

D  Monocytes; basophils

E  T cells; B cells

A  Include leukocytes that are either granulocytes or agranulocytes

B  Develop from undifferentiated stem cells

C  Include Kupffer cells

D  After birth, produced in red bone marrow sites

E  Include erythrocytes that, when mature, lose their nuclei

A  chemotaxis

B  vasodilation

C  diapedesis

D  phagocytosis

E  motility

A  tonsils

B  thymus

C  spleen

D  GALT

E  lymph nodes

A  Host defenses due to B and T cells and their products
Use of drugs and antibiotics
Anatomical and physiological barriers

B  Internal cellular and chemical defenses
Phagocytosis and inflammation
Anatomical and physiological barriers

C  Host defenses due to B and T cells and their products
Use of drugs and antibiotics

D  Internal cellular and chemical defenses
Use of drugs and antibiotics
Host defenses due to B and T cells and their products

A  creates a physical barrier against pathogens

B  None of the choices are correct.

C  destroys pathogens

D  is toxic to pathogens

E  physically restricts pathogens to a specific region