Lecture Exam 4 (Ch 12, 13, 14)

A  delayed

B  atopic

C  antibody mediated

D  systemic anaphylactic

E  T-cell mediated

A  maternal Rh + cells enter an Rh -fetus

B  maternal Rh ˗ cells enter an Rh + fetus

C  fetal Rh ˗ cells enter an Rh + mother

D  fetal Rh + cells enter an Rh – mother

E  fetal Rh + cells enter an Rh + mother

A  transfusion reaction

B  immunodeficiency

C  hypersensitivity

D  autoimmune disease

E  desensitization

A  hemopathology

B  epidemiology

C  humoralpathology

D  immunopathology

E  histopathology

A  foreign cells

B  IgM

C  complement

D  IgG

E  IgE

A  rheumatic fever

B  type I diabetes

C  Graves’ disease

D  metastatic cancer

E  systemic lupus erythematosus

A  isograft

B    

C  allograft

D  autograft

E  hypograft

F  xenograft

A  Inhalant

B  Contactant

C  None of the choices are correct.

D  Injectant

E  Ingestant

A  pruritus and headache

B  relaxes vascular smooth muscle

C  increased sensitivity to pain

D  wheal and flare reaction in skin

E  constriction of smooth muscle of bronchi and the intestine

A  type I and type IV

B  type IV only

C  type I, type II, type III, and type IV

D  type I only

E  type I, type II, and type III

A  a deficiency in T-cell development

B  graft rejection

C  autoantibodies and T cells

D  IgE and mast cells

E  a transfusion reaction

A  Diarrhea

B  Sneezing

C  Rhinitis

D  Rashes

E  Contact dermatitis

A  inhibit the activity of lymphocytes

B  bind to histamine receptors on target organs

C  relieve inflammatory symptoms

D  block synthesis of leukotrienes

E  reverse spasms of respiratory smooth muscles

A  Binding of IgE by the Fc region to mast cells and basophils

B  Degranulation

C  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

D  Histamine acts on smooth muscle

E  Prostaglandins cause vasodilation and increased vascular permeability

A  acetylcholine receptors on skeletal muscle

B  cells in thyroid follicles

C  acetylcholine receptors on smooth muscle

D  sodium pump proteins in the cell membrane

E  myelin sheath cells of the nervous system

A  Involves production of IgG and IgE antibodies

B  Involves an immune complex reaction

C  Antigen-antibody complexes are deposited in the basement membrane of epithelial tissues

D  Serum sickness is a systemic response

E  The Arthus reaction is a local response

A  allergic rhinitis

B  asthma

C  atopic dermatitis

D  anaphylaxis

E  eczema

A  Blood transfusion

B  All of thechoices are correct.

C  Skin graft

D  Both skin graft and organ transplantation

E  Organ transplantation

A  desensitization

B  None of thechoices are correct.

C  sensitization

D  tissue matching

E  degranulation

A  Prostaglandins cause vasodilation and increased vascular permeability

B  Degranulation

C  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

D  Binding of IgE by the Fc region to mast cells and basophils

E  Histamine acts on smooth muscle

A  Hypogammaglobulinemia

B  Host rejection of graft

C  None of the choices are correct.

D  Graft versus host disease

E  Formation of autoantibodies

A  Antibody mediated

B  Immune complex mediated

C  Both anaphylaxis and antibody mediated

D  Anaphylaxis

E  Both antibody mediated and immune complex mediated

A  tuberculin reaction

B  rheumatoid arthritis

C  myasthenia gravis

D  Graves’ disease

E  multiple sclerosis

A  histamine

B  platelet-activating factor

C  prostaglandin

D  serotonin

E  leukotriene

A  disulfide bonds between polypeptide chains

B  two identical light polypeptide chains

C  two identical heavy polypeptide chains

D  a variable and constant region on each polypeptide chain

E  four antigen binding sites

A  T cells maturing in the thymus

B  All of the choices are correct.

C  B cells maturing in bone marrow sites

D  release of mature lymphocytes to begin migration to various lymphoid organs

E  hormonal signals that initiate development

A  variable

B  Fab

C  hinge

D  terminal

E  Fc

A  suppress immune reactions

B  secrete antibodies

C  directly destroy target cells

D  function in allergic reactions

E  activate B cells and other T cells

A  hold and present processed antigen on their cell membrane surface

B  include macrophages

C  All of the choices are correct.

D  engulf and modify antigen to be more immunogenic

E  include dendritic cells

A  false

B  true

A  interleukin-1 activating the T helper cell

B  binding of T-cell to a class II MHC receptor on a macrophage

C  All of the choices are correct.

D  typically a protein antigen

E    

F  binding of T-cell to a site on the antigen

A  IgD

B  IgA

C  IgE

D  IgM

E  IgG

A  secrete antibodies

B  suppress immune reactions

C  activate B cells and other T cells

D  function in allergic reactions

E  directly destroy target cells

A  None of the choices are correct.

B  antigen binding site

C  epitope

D  variable region

E  hapten

A  aid in cellular development

B  are the result of genetic expression

C  receive and transmit chemical messages among other cells of the system

D  function in recognition of self molecules

E  All of the choices are correct.

A  have large polymers made up of repeating subunits

B  have molecular complexity

C  are foreign to the immune system

D  are large molecules with a minimum molecular weight of 1,000

E  are cells or large, complex molecules

A  superantigens

B  allergens

C  None of the choices are correct.

D  autoantigens

E  heterophilic antigens

A  cytotoxic T cells

B  delayed hypersensitivity T cells

C  natural killer (NK) cells

D  suppressor T cells

E  helper T cells

A  Cytotoxic T cells

B  Antigen-presenting cells

C  B cells

D  Plasma cells

E  Helper T cells

A  all HLA antigens

B  self receptors recognized by T lymphocytes

C  All of the choices are correct.

D  certain secreted complement components

E  receptors located primarily on macrophages and B cells

A  true

B  false

A  can serve as a B-cell receptor

B  is the first class synthesized by a plasma cell

C  contains a central J chain

D  is a dimer

E  has 10 antigen binding sites

A  bacterial toxins that activate T cells at a 100 times greater rate than other antigens

B  cell markers found in some member of a species but not in other members

C  body tissues that the immune system mistakes as foreign

D  None of the choices are correct.

E  those that evoke allergic reactions

A  false

B  true

A  IgA

B  IgG

C  IgM

D  IgE

E  IgD

A  have membrane receptors that recognize foreign antigens

B  gain tolerance to self by destruction of lymphocytes that could react against self

C  possess MHC antigens for recognizing self

D  All of the choices are correct.

E  develop into clones of B and T cells with extreme variations of specificity

A  glycoproteins, called MHC antigens, found on all body cells

B  located in the thymus gland

C  found on the third chromosome

D    

E  a set of genes that code for MHC glycoproteins

F  All of the choices are correct.

A  leukocytes

B  eosinophils

C  islet of Langerhans cells

D  epithelial cells

E  red blood cells

A  IgD only

B  IgM and IgD

C  IgM only

D  IgD and IgE

E  IgG only

A  Respiratory tract

B  Skin

C  Digestive tract

D  Urinary tract

E  Eyes

A  increases the availability of iron

B  increases phagocytosis

C  increases metabolism

D  stimulates hematopoiesis

E  reduces the ability of temperature-sensitive organisms to multiply

A  Includes chemicals such as lysozyme and lactic acid
Involves barriers at portals of entry
Examples include the ciliated epithelium of the respiratory passages, excretion of urine, and production of tears

B  Includes chemicals such as lysozyme and lactic acid
Involves recognition of foreign agents by their pathogen-associated molecular patterns

C  Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

D  Involves barriers at portals of entry
Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

A  monocytes

B  lymphocytes

C  neutrophils

D  basophils

E  eosinophils

A  neutrophils

B  killer T cells

C  macrophages

D  primary phagocytes

E  cytotoxic T cells

A  dendritic cells

B  eosinophils

C  macrophages

D  platelets

E  mast cells

A  Monocytes

B  Lymphocytes

C  Basophils

D  Eosinophils

E  Neutrophils

A  warmth

B  pain

C  swelling

D  redness

E  chills

A  digestive enzymes

B  antibodies

C  antigens

D  histamine

E  lysozyme

A  None of the choices are correct.

B  granulocytes

C  agranulocytes

D  monocytes

E  leukocytes

A  Start tissue repair

B  Mobilize and attract immune components to injury site

C  Destroy microbes

D  Cause a fever

E  Block further invasion

A  production of only red blood cells

B  migration of white blood cells from the blood out to the tissues

C  loss of blood due to hemorrhaging

D  plugging of broken vessels to stop bleeding

E  production of white blood cells, red blood cells, and platelets

A  T cells

B  hairs

C  unbroken skin

D  tears

E  mucus

A  is mostly water

B  All of the choices are correct.

C  contains albumin and globulins

D  contains fibrinogen

E  is the liquid portion of blood in which blood cells are suspended

A  None of these are mismatched.

B  Tumor—cancer

C  Rubor—redness

D  Calor—warmth

E  Dolar—pain

A  Serotonin causes smooth muscle contraction.

B  Pyrogens cause vasodilation and increased capillary permeability.

C  Fever could be beneficial to inhibiting the pathogen.

D  Basophils and mast cells release histamine.

E  It can last hours to years.

A  digestive tract

B  skin

C  respiratory tract

D  eyes

E  urinary tract

A  Bloodstream

B  Intracellular fluid

C  Extracellular fluid

D  Lymphatic system

A  Basophils; T cells

B  B cells; neutrophils

C  Monocytes; basophils

D  T cells; B cells

E  B cells; T cells

A  Include Kupffer cells

B  After birth, produced in red bone marrow sites

C  Include erythrocytes that, when mature, lose their nuclei

D  Include leukocytes that are either granulocytes or agranulocytes

E  Develop from undifferentiated stem cells

A  motility

B  chemotaxis

C  phagocytosis

D  vasodilation

E  diapedesis

A  spleen

B  lymph nodes

C  GALT

D  thymus

E  tonsils

A  Host defenses due to B and T cells and their products
Use of drugs and antibiotics

B  Internal cellular and chemical defenses
Use of drugs and antibiotics
Host defenses due to B and T cells and their products

C  Internal cellular and chemical defenses
Phagocytosis and inflammation
Anatomical and physiological barriers

D  Host defenses due to B and T cells and their products
Use of drugs and antibiotics
Anatomical and physiological barriers

A  destroys pathogens

B  is toxic to pathogens

C  physically restricts pathogens to a specific region

D  None of the choices are correct.

E  creates a physical barrier against pathogens