Lecture Exam 4 (Ch 12, 13, 14)

A  atopic

B  antibody mediated

C  delayed

D  systemic anaphylactic

E  T-cell mediated

A  fetal Rh + cells enter an Rh + mother

B  maternal Rh ˗ cells enter an Rh + fetus

C  fetal Rh + cells enter an Rh – mother

D  maternal Rh + cells enter an Rh -fetus

E  fetal Rh ˗ cells enter an Rh + mother

A  hypersensitivity

B  desensitization

C  autoimmune disease

D  immunodeficiency

E  transfusion reaction

A  humoralpathology

B  histopathology

C  hemopathology

D  epidemiology

E  immunopathology

A  IgM

B  complement

C  IgE

D  foreign cells

E  IgG

A  rheumatic fever

B  Graves’ disease

C  systemic lupus erythematosus

D  type I diabetes

E  metastatic cancer

A  hypograft

B  isograft

C  xenograft

D    

E  autograft

F  allograft

A  Inhalant

B  Ingestant

C  Injectant

D  None of the choices are correct.

E  Contactant

A  wheal and flare reaction in skin

B  relaxes vascular smooth muscle

C  constriction of smooth muscle of bronchi and the intestine

D  pruritus and headache

E  increased sensitivity to pain

A  type I only

B  type I and type IV

C  type I, type II, type III, and type IV

D  type IV only

E  type I, type II, and type III

A  autoantibodies and T cells

B  graft rejection

C  a deficiency in T-cell development

D  IgE and mast cells

E  a transfusion reaction

A  Contact dermatitis

B  Rashes

C  Rhinitis

D  Diarrhea

E  Sneezing

A  block synthesis of leukotrienes

B  reverse spasms of respiratory smooth muscles

C  relieve inflammatory symptoms

D  bind to histamine receptors on target organs

E  inhibit the activity of lymphocytes

A  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

B  Histamine acts on smooth muscle

C  Prostaglandins cause vasodilation and increased vascular permeability

D  Degranulation

E  Binding of IgE by the Fc region to mast cells and basophils

A  sodium pump proteins in the cell membrane

B  acetylcholine receptors on smooth muscle

C  cells in thyroid follicles

D  acetylcholine receptors on skeletal muscle

E  myelin sheath cells of the nervous system

A  Serum sickness is a systemic response

B  The Arthus reaction is a local response

C  Antigen-antibody complexes are deposited in the basement membrane of epithelial tissues

D  Involves an immune complex reaction

E  Involves production of IgG and IgE antibodies

A  eczema

B  atopic dermatitis

C  anaphylaxis

D  asthma

E  allergic rhinitis

A  Organ transplantation

B  Blood transfusion

C  Both skin graft and organ transplantation

D  All of thechoices are correct.

E  Skin graft

A  desensitization

B  degranulation

C  tissue matching

D  sensitization

E  None of thechoices are correct.

A  Prostaglandins cause vasodilation and increased vascular permeability

B  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

C  Binding of IgE by the Fc region to mast cells and basophils

D  Degranulation

E  Histamine acts on smooth muscle

A  Graft versus host disease

B  None of the choices are correct.

C  Host rejection of graft

D  Formation of autoantibodies

E  Hypogammaglobulinemia

A  Antibody mediated

B  Both anaphylaxis and antibody mediated

C  Immune complex mediated

D  Anaphylaxis

E  Both antibody mediated and immune complex mediated

A  rheumatoid arthritis

B  tuberculin reaction

C  myasthenia gravis

D  Graves’ disease

E  multiple sclerosis

A  platelet-activating factor

B  prostaglandin

C  histamine

D  leukotriene

E  serotonin

A  four antigen binding sites

B  a variable and constant region on each polypeptide chain

C  disulfide bonds between polypeptide chains

D  two identical light polypeptide chains

E  two identical heavy polypeptide chains

A  B cells maturing in bone marrow sites

B  release of mature lymphocytes to begin migration to various lymphoid organs

C  hormonal signals that initiate development

D  All of the choices are correct.

E  T cells maturing in the thymus

A  hinge

B  terminal

C  variable

D  Fc

E  Fab

A  suppress immune reactions

B  secrete antibodies

C  function in allergic reactions

D  directly destroy target cells

E  activate B cells and other T cells

A  hold and present processed antigen on their cell membrane surface

B  include macrophages

C  All of the choices are correct.

D  include dendritic cells

E  engulf and modify antigen to be more immunogenic

A  false

B  true

A  binding of T-cell to a site on the antigen

B  All of the choices are correct.

C  binding of T-cell to a class II MHC receptor on a macrophage

D  typically a protein antigen

E    

F  interleukin-1 activating the T helper cell

A  IgD

B  IgG

C  IgM

D  IgE

E  IgA

A  function in allergic reactions

B  activate B cells and other T cells

C  suppress immune reactions

D  directly destroy target cells

E  secrete antibodies

A  epitope

B  hapten

C  variable region

D  antigen binding site

E  None of the choices are correct.

A  are the result of genetic expression

B  receive and transmit chemical messages among other cells of the system

C  aid in cellular development

D  All of the choices are correct.

E  function in recognition of self molecules

A  have molecular complexity

B  are foreign to the immune system

C  are cells or large, complex molecules

D  have large polymers made up of repeating subunits

E  are large molecules with a minimum molecular weight of 1,000

A  heterophilic antigens

B  None of the choices are correct.

C  autoantigens

D  superantigens

E  allergens

A  helper T cells

B  natural killer (NK) cells

C  suppressor T cells

D  delayed hypersensitivity T cells

E  cytotoxic T cells

A  Cytotoxic T cells

B  B cells

C  Plasma cells

D  Antigen-presenting cells

E  Helper T cells

A  all HLA antigens

B  certain secreted complement components

C  receptors located primarily on macrophages and B cells

D  self receptors recognized by T lymphocytes

E  All of the choices are correct.

A  true

B  false

A  can serve as a B-cell receptor

B  has 10 antigen binding sites

C  contains a central J chain

D  is a dimer

E  is the first class synthesized by a plasma cell

A  cell markers found in some member of a species but not in other members

B  bacterial toxins that activate T cells at a 100 times greater rate than other antigens

C  body tissues that the immune system mistakes as foreign

D  None of the choices are correct.

E  those that evoke allergic reactions

A  true

B  false

A  IgA

B  IgG

C  IgM

D  IgE

E  IgD

A  gain tolerance to self by destruction of lymphocytes that could react against self

B  All of the choices are correct.

C  develop into clones of B and T cells with extreme variations of specificity

D  have membrane receptors that recognize foreign antigens

E  possess MHC antigens for recognizing self

A  glycoproteins, called MHC antigens, found on all body cells

B  located in the thymus gland

C    

D  a set of genes that code for MHC glycoproteins

E  found on the third chromosome

F  All of the choices are correct.

A  leukocytes

B  eosinophils

C  red blood cells

D  islet of Langerhans cells

E  epithelial cells

A  IgM only

B  IgG only

C  IgD and IgE

D  IgD only

E  IgM and IgD

A  Urinary tract

B  Respiratory tract

C  Eyes

D  Skin

E  Digestive tract

A  reduces the ability of temperature-sensitive organisms to multiply

B  increases metabolism

C  increases phagocytosis

D  stimulates hematopoiesis

E  increases the availability of iron

A  Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

B  Includes chemicals such as lysozyme and lactic acid
Involves barriers at portals of entry
Examples include the ciliated epithelium of the respiratory passages, excretion of urine, and production of tears

C  Includes chemicals such as lysozyme and lactic acid
Involves recognition of foreign agents by their pathogen-associated molecular patterns

D  Involves barriers at portals of entry
Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

A  eosinophils

B  basophils

C  lymphocytes

D  neutrophils

E  monocytes

A  macrophages

B  cytotoxic T cells

C  killer T cells

D  primary phagocytes

E  neutrophils

A  mast cells

B  macrophages

C  dendritic cells

D  eosinophils

E  platelets

A  Lymphocytes

B  Neutrophils

C  Monocytes

D  Eosinophils

E  Basophils

A  redness

B  pain

C  swelling

D  chills

E  warmth

A  antibodies

B  digestive enzymes

C  histamine

D  lysozyme

E  antigens

A  agranulocytes

B  leukocytes

C  granulocytes

D  monocytes

E  None of the choices are correct.

A  Start tissue repair

B  Block further invasion

C  Cause a fever

D  Destroy microbes

E  Mobilize and attract immune components to injury site

A  migration of white blood cells from the blood out to the tissues

B  production of white blood cells, red blood cells, and platelets

C  loss of blood due to hemorrhaging

D  production of only red blood cells

E  plugging of broken vessels to stop bleeding

A  T cells

B  mucus

C  unbroken skin

D  hairs

E  tears

A  is the liquid portion of blood in which blood cells are suspended

B  All of the choices are correct.

C  is mostly water

D  contains fibrinogen

E  contains albumin and globulins

A  Dolar—pain

B  Calor—warmth

C  Tumor—cancer

D  None of these are mismatched.

E  Rubor—redness

A  Basophils and mast cells release histamine.

B  It can last hours to years.

C  Serotonin causes smooth muscle contraction.

D  Fever could be beneficial to inhibiting the pathogen.

E  Pyrogens cause vasodilation and increased capillary permeability.

A  urinary tract

B  digestive tract

C  eyes

D  skin

E  respiratory tract

A  Extracellular fluid

B  Intracellular fluid

C  Lymphatic system

D  Bloodstream

A  T cells; B cells

B  Basophils; T cells

C  B cells; neutrophils

D  Monocytes; basophils

E  B cells; T cells

A  After birth, produced in red bone marrow sites

B  Include Kupffer cells

C  Include erythrocytes that, when mature, lose their nuclei

D  Include leukocytes that are either granulocytes or agranulocytes

E  Develop from undifferentiated stem cells

A  motility

B  chemotaxis

C  vasodilation

D  phagocytosis

E  diapedesis

A  tonsils

B  GALT

C  lymph nodes

D  spleen

E  thymus

A  Host defenses due to B and T cells and their products
Use of drugs and antibiotics
Anatomical and physiological barriers

B  Internal cellular and chemical defenses
Phagocytosis and inflammation
Anatomical and physiological barriers

C  Internal cellular and chemical defenses
Use of drugs and antibiotics
Host defenses due to B and T cells and their products

D  Host defenses due to B and T cells and their products
Use of drugs and antibiotics

A  is toxic to pathogens

B  creates a physical barrier against pathogens

C  None of the choices are correct.

D  physically restricts pathogens to a specific region

E  destroys pathogens