Lecture Exam 4 (Ch 12, 13, 14)

A  delayed

B  atopic

C  systemic anaphylactic

D  T-cell mediated

E  antibody mediated

A  fetal Rh + cells enter an Rh – mother

B  maternal Rh + cells enter an Rh -fetus

C  fetal Rh + cells enter an Rh + mother

D  fetal Rh ˗ cells enter an Rh + mother

E  maternal Rh ˗ cells enter an Rh + fetus

A  hypersensitivity

B  immunodeficiency

C  desensitization

D  transfusion reaction

E  autoimmune disease

A  immunopathology

B  hemopathology

C  epidemiology

D  humoralpathology

E  histopathology

A  IgM

B  IgG

C  IgE

D  foreign cells

E  complement

A  rheumatic fever

B  metastatic cancer

C  Graves’ disease

D  type I diabetes

E  systemic lupus erythematosus

A  autograft

B  allograft

C  hypograft

D  isograft

E    

F  xenograft

A  Inhalant

B  None of the choices are correct.

C  Ingestant

D  Injectant

E  Contactant

A  wheal and flare reaction in skin

B  pruritus and headache

C  constriction of smooth muscle of bronchi and the intestine

D  increased sensitivity to pain

E  relaxes vascular smooth muscle

A  type I, type II, and type III

B  type I and type IV

C  type I only

D  type I, type II, type III, and type IV

E  type IV only

A  a transfusion reaction

B  autoantibodies and T cells

C  graft rejection

D  a deficiency in T-cell development

E  IgE and mast cells

A  Sneezing

B  Diarrhea

C  Rhinitis

D  Rashes

E  Contact dermatitis

A  reverse spasms of respiratory smooth muscles

B  relieve inflammatory symptoms

C  bind to histamine receptors on target organs

D  inhibit the activity of lymphocytes

E  block synthesis of leukotrienes

A  Binding of IgE by the Fc region to mast cells and basophils

B  Histamine acts on smooth muscle

C  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

D  Prostaglandins cause vasodilation and increased vascular permeability

E  Degranulation

A  cells in thyroid follicles

B  acetylcholine receptors on skeletal muscle

C  myelin sheath cells of the nervous system

D  sodium pump proteins in the cell membrane

E  acetylcholine receptors on smooth muscle

A  Antigen-antibody complexes are deposited in the basement membrane of epithelial tissues

B  Involves an immune complex reaction

C  The Arthus reaction is a local response

D  Serum sickness is a systemic response

E  Involves production of IgG and IgE antibodies

A  allergic rhinitis

B  asthma

C  eczema

D  atopic dermatitis

E  anaphylaxis

A  All of thechoices are correct.

B  Organ transplantation

C  Skin graft

D  Both skin graft and organ transplantation

E  Blood transfusion

A  tissue matching

B  None of thechoices are correct.

C  degranulation

D  sensitization

E  desensitization

A  Degranulation

B  Histamine acts on smooth muscle

C  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

D  Binding of IgE by the Fc region to mast cells and basophils

E  Prostaglandins cause vasodilation and increased vascular permeability

A  None of the choices are correct.

B  Formation of autoantibodies

C  Hypogammaglobulinemia

D  Graft versus host disease

E  Host rejection of graft

A  Both anaphylaxis and antibody mediated

B  Antibody mediated

C  Immune complex mediated

D  Both antibody mediated and immune complex mediated

E  Anaphylaxis

A  tuberculin reaction

B  multiple sclerosis

C  Graves’ disease

D  myasthenia gravis

E  rheumatoid arthritis

A  serotonin

B  prostaglandin

C  platelet-activating factor

D  histamine

E  leukotriene

A  four antigen binding sites

B  two identical light polypeptide chains

C  disulfide bonds between polypeptide chains

D  two identical heavy polypeptide chains

E  a variable and constant region on each polypeptide chain

A  release of mature lymphocytes to begin migration to various lymphoid organs

B  hormonal signals that initiate development

C  All of the choices are correct.

D  B cells maturing in bone marrow sites

E  T cells maturing in the thymus

A  Fab

B  hinge

C  Fc

D  variable

E  terminal

A  secrete antibodies

B  activate B cells and other T cells

C  directly destroy target cells

D  suppress immune reactions

E  function in allergic reactions

A  hold and present processed antigen on their cell membrane surface

B  engulf and modify antigen to be more immunogenic

C  All of the choices are correct.

D  include dendritic cells

E  include macrophages

A  true

B  false

A  binding of T-cell to a class II MHC receptor on a macrophage

B  typically a protein antigen

C  binding of T-cell to a site on the antigen

D    

E  interleukin-1 activating the T helper cell

F  All of the choices are correct.

A  IgG

B  IgE

C  IgM

D  IgD

E  IgA

A  directly destroy target cells

B  suppress immune reactions

C  function in allergic reactions

D  secrete antibodies

E  activate B cells and other T cells

A  hapten

B  epitope

C  antigen binding site

D  variable region

E  None of the choices are correct.

A  aid in cellular development

B  are the result of genetic expression

C  receive and transmit chemical messages among other cells of the system

D  All of the choices are correct.

E  function in recognition of self molecules

A  have molecular complexity

B  are large molecules with a minimum molecular weight of 1,000

C  are foreign to the immune system

D  have large polymers made up of repeating subunits

E  are cells or large, complex molecules

A  autoantigens

B  heterophilic antigens

C  superantigens

D  allergens

E  None of the choices are correct.

A  cytotoxic T cells

B  delayed hypersensitivity T cells

C  suppressor T cells

D  natural killer (NK) cells

E  helper T cells

A  Cytotoxic T cells

B  Plasma cells

C  Helper T cells

D  Antigen-presenting cells

E  B cells

A  all HLA antigens

B  self receptors recognized by T lymphocytes

C  certain secreted complement components

D  All of the choices are correct.

E  receptors located primarily on macrophages and B cells

A  false

B  true

A  is the first class synthesized by a plasma cell

B  contains a central J chain

C  can serve as a B-cell receptor

D  is a dimer

E  has 10 antigen binding sites

A  those that evoke allergic reactions

B  cell markers found in some member of a species but not in other members

C  bacterial toxins that activate T cells at a 100 times greater rate than other antigens

D  None of the choices are correct.

E  body tissues that the immune system mistakes as foreign

A  false

B  true

A  IgD

B  IgM

C  IgG

D  IgE

E  IgA

A  possess MHC antigens for recognizing self

B  All of the choices are correct.

C  have membrane receptors that recognize foreign antigens

D  develop into clones of B and T cells with extreme variations of specificity

E  gain tolerance to self by destruction of lymphocytes that could react against self

A  located in the thymus gland

B    

C  All of the choices are correct.

D  found on the third chromosome

E  glycoproteins, called MHC antigens, found on all body cells

F  a set of genes that code for MHC glycoproteins

A  leukocytes

B  red blood cells

C  epithelial cells

D  eosinophils

E  islet of Langerhans cells

A  IgD only

B  IgM and IgD

C  IgD and IgE

D  IgG only

E  IgM only

A  Respiratory tract

B  Skin

C  Eyes

D  Digestive tract

E  Urinary tract

A  reduces the ability of temperature-sensitive organisms to multiply

B  increases the availability of iron

C  increases metabolism

D  increases phagocytosis

E  stimulates hematopoiesis

A  Includes chemicals such as lysozyme and lactic acid
Involves recognition of foreign agents by their pathogen-associated molecular patterns

B  Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

C  Involves barriers at portals of entry
Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

D  Includes chemicals such as lysozyme and lactic acid
Involves barriers at portals of entry
Examples include the ciliated epithelium of the respiratory passages, excretion of urine, and production of tears

A  lymphocytes

B  monocytes

C  eosinophils

D  basophils

E  neutrophils

A  cytotoxic T cells

B  neutrophils

C  killer T cells

D  primary phagocytes

E  macrophages

A  mast cells

B  eosinophils

C  macrophages

D  dendritic cells

E  platelets

A  Eosinophils

B  Monocytes

C  Lymphocytes

D  Basophils

E  Neutrophils

A  redness

B  warmth

C  pain

D  chills

E  swelling

A  digestive enzymes

B  antigens

C  lysozyme

D  histamine

E  antibodies

A  leukocytes

B  None of the choices are correct.

C  granulocytes

D  agranulocytes

E  monocytes

A  Destroy microbes

B  Block further invasion

C  Mobilize and attract immune components to injury site

D  Cause a fever

E  Start tissue repair

A  migration of white blood cells from the blood out to the tissues

B  loss of blood due to hemorrhaging

C  production of white blood cells, red blood cells, and platelets

D  production of only red blood cells

E  plugging of broken vessels to stop bleeding

A  tears

B  mucus

C  hairs

D  T cells

E  unbroken skin

A  contains albumin and globulins

B  All of the choices are correct.

C  is the liquid portion of blood in which blood cells are suspended

D  is mostly water

E  contains fibrinogen

A  None of these are mismatched.

B  Dolar—pain

C  Tumor—cancer

D  Calor—warmth

E  Rubor—redness

A  Serotonin causes smooth muscle contraction.

B  It can last hours to years.

C  Fever could be beneficial to inhibiting the pathogen.

D  Basophils and mast cells release histamine.

E  Pyrogens cause vasodilation and increased capillary permeability.

A  eyes

B  skin

C  urinary tract

D  digestive tract

E  respiratory tract

A  Bloodstream

B  Lymphatic system

C  Intracellular fluid

D  Extracellular fluid

A  B cells; neutrophils

B  Basophils; T cells

C  Monocytes; basophils

D  B cells; T cells

E  T cells; B cells

A  Include Kupffer cells

B  After birth, produced in red bone marrow sites

C  Include erythrocytes that, when mature, lose their nuclei

D  Develop from undifferentiated stem cells

E  Include leukocytes that are either granulocytes or agranulocytes

A  vasodilation

B  chemotaxis

C  diapedesis

D  phagocytosis

E  motility

A  tonsils

B  thymus

C  GALT

D  lymph nodes

E  spleen

A  Internal cellular and chemical defenses
Phagocytosis and inflammation
Anatomical and physiological barriers

B  Host defenses due to B and T cells and their products
Use of drugs and antibiotics

C  Host defenses due to B and T cells and their products
Use of drugs and antibiotics
Anatomical and physiological barriers

D  Internal cellular and chemical defenses
Use of drugs and antibiotics
Host defenses due to B and T cells and their products

A  None of the choices are correct.

B  physically restricts pathogens to a specific region

C  creates a physical barrier against pathogens

D  destroys pathogens

E  is toxic to pathogens