Lecture Exam 4 (Ch 12, 13, 14)

A  antibody mediated

B  delayed

C  T-cell mediated

D  atopic

E  systemic anaphylactic

A  maternal Rh + cells enter an Rh -fetus

B  fetal Rh + cells enter an Rh + mother

C  maternal Rh ˗ cells enter an Rh + fetus

D  fetal Rh ˗ cells enter an Rh + mother

E  fetal Rh + cells enter an Rh – mother

A  hypersensitivity

B  desensitization

C  autoimmune disease

D  transfusion reaction

E  immunodeficiency

A  histopathology

B  immunopathology

C  humoralpathology

D  epidemiology

E  hemopathology

A  IgM

B  IgG

C  foreign cells

D  complement

E  IgE

A  metastatic cancer

B  systemic lupus erythematosus

C  rheumatic fever

D  type I diabetes

E  Graves’ disease

A  isograft

B  autograft

C  hypograft

D  xenograft

E    

F  allograft

A  Inhalant

B  None of the choices are correct.

C  Contactant

D  Injectant

E  Ingestant

A  pruritus and headache

B  constriction of smooth muscle of bronchi and the intestine

C  increased sensitivity to pain

D  wheal and flare reaction in skin

E  relaxes vascular smooth muscle

A  type I only

B  type IV only

C  type I, type II, type III, and type IV

D  type I, type II, and type III

E  type I and type IV

A  IgE and mast cells

B  a deficiency in T-cell development

C  graft rejection

D  a transfusion reaction

E  autoantibodies and T cells

A  Sneezing

B  Rhinitis

C  Rashes

D  Contact dermatitis

E  Diarrhea

A  block synthesis of leukotrienes

B  inhibit the activity of lymphocytes

C  bind to histamine receptors on target organs

D  relieve inflammatory symptoms

E  reverse spasms of respiratory smooth muscles

A  Binding of IgE by the Fc region to mast cells and basophils

B  Histamine acts on smooth muscle

C  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

D  Degranulation

E  Prostaglandins cause vasodilation and increased vascular permeability

A  acetylcholine receptors on smooth muscle

B  acetylcholine receptors on skeletal muscle

C  myelin sheath cells of the nervous system

D  sodium pump proteins in the cell membrane

E  cells in thyroid follicles

A  Antigen-antibody complexes are deposited in the basement membrane of epithelial tissues

B  Involves an immune complex reaction

C  Involves production of IgG and IgE antibodies

D  The Arthus reaction is a local response

E  Serum sickness is a systemic response

A  anaphylaxis

B  allergic rhinitis

C  atopic dermatitis

D  asthma

E  eczema

A  Both skin graft and organ transplantation

B  Organ transplantation

C  Blood transfusion

D  All of thechoices are correct.

E  Skin graft

A  desensitization

B  degranulation

C  tissue matching

D  sensitization

E  None of thechoices are correct.

A  Binding of IgE by the Fc region to mast cells and basophils

B  Histamine acts on smooth muscle

C  Degranulation

D  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

E  Prostaglandins cause vasodilation and increased vascular permeability

A  Host rejection of graft

B  Hypogammaglobulinemia

C  Graft versus host disease

D  None of the choices are correct.

E  Formation of autoantibodies

A  Immune complex mediated

B  Antibody mediated

C  Both anaphylaxis and antibody mediated

D  Anaphylaxis

E  Both antibody mediated and immune complex mediated

A  Graves’ disease

B  tuberculin reaction

C  myasthenia gravis

D  multiple sclerosis

E  rheumatoid arthritis

A  platelet-activating factor

B  serotonin

C  histamine

D  prostaglandin

E  leukotriene

A  disulfide bonds between polypeptide chains

B  two identical heavy polypeptide chains

C  two identical light polypeptide chains

D  four antigen binding sites

E  a variable and constant region on each polypeptide chain

A  T cells maturing in the thymus

B  All of the choices are correct.

C  release of mature lymphocytes to begin migration to various lymphoid organs

D  B cells maturing in bone marrow sites

E  hormonal signals that initiate development

A  Fc

B  variable

C  terminal

D  hinge

E  Fab

A  directly destroy target cells

B  secrete antibodies

C  function in allergic reactions

D  activate B cells and other T cells

E  suppress immune reactions

A  hold and present processed antigen on their cell membrane surface

B  include dendritic cells

C  include macrophages

D  engulf and modify antigen to be more immunogenic

E  All of the choices are correct.

A  true

B  false

A  interleukin-1 activating the T helper cell

B  All of the choices are correct.

C  binding of T-cell to a class II MHC receptor on a macrophage

D  binding of T-cell to a site on the antigen

E  typically a protein antigen

F    

A  IgD

B  IgE

C  IgA

D  IgG

E  IgM

A  secrete antibodies

B  directly destroy target cells

C  function in allergic reactions

D  activate B cells and other T cells

E  suppress immune reactions

A  variable region

B  None of the choices are correct.

C  epitope

D  antigen binding site

E  hapten

A  receive and transmit chemical messages among other cells of the system

B  aid in cellular development

C  All of the choices are correct.

D  function in recognition of self molecules

E  are the result of genetic expression

A  are cells or large, complex molecules

B  have large polymers made up of repeating subunits

C  have molecular complexity

D  are foreign to the immune system

E  are large molecules with a minimum molecular weight of 1,000

A  autoantigens

B  superantigens

C  None of the choices are correct.

D  heterophilic antigens

E  allergens

A  suppressor T cells

B  cytotoxic T cells

C  natural killer (NK) cells

D  helper T cells

E  delayed hypersensitivity T cells

A  Cytotoxic T cells

B  Antigen-presenting cells

C  B cells

D  Plasma cells

E  Helper T cells

A  certain secreted complement components

B  self receptors recognized by T lymphocytes

C  All of the choices are correct.

D  receptors located primarily on macrophages and B cells

E  all HLA antigens

A  false

B  true

A  contains a central J chain

B  can serve as a B-cell receptor

C  has 10 antigen binding sites

D  is a dimer

E  is the first class synthesized by a plasma cell

A  those that evoke allergic reactions

B  cell markers found in some member of a species but not in other members

C  body tissues that the immune system mistakes as foreign

D  None of the choices are correct.

E  bacterial toxins that activate T cells at a 100 times greater rate than other antigens

A  true

B  false

A  IgD

B  IgG

C  IgE

D  IgA

E  IgM

A  have membrane receptors that recognize foreign antigens

B  possess MHC antigens for recognizing self

C  gain tolerance to self by destruction of lymphocytes that could react against self

D  All of the choices are correct.

E  develop into clones of B and T cells with extreme variations of specificity

A  a set of genes that code for MHC glycoproteins

B    

C  All of the choices are correct.

D  glycoproteins, called MHC antigens, found on all body cells

E  located in the thymus gland

F  found on the third chromosome

A  eosinophils

B  islet of Langerhans cells

C  epithelial cells

D  leukocytes

E  red blood cells

A  IgG only

B  IgD and IgE

C  IgD only

D  IgM only

E  IgM and IgD

A  Digestive tract

B  Eyes

C  Skin

D  Respiratory tract

E  Urinary tract

A  reduces the ability of temperature-sensitive organisms to multiply

B  increases phagocytosis

C  increases metabolism

D  increases the availability of iron

E  stimulates hematopoiesis

A  Includes chemicals such as lysozyme and lactic acid
Involves barriers at portals of entry
Examples include the ciliated epithelium of the respiratory passages, excretion of urine, and production of tears

B  Involves barriers at portals of entry
Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

C  Includes chemicals such as lysozyme and lactic acid
Involves recognition of foreign agents by their pathogen-associated molecular patterns

D  Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

A  basophils

B  eosinophils

C  monocytes

D  lymphocytes

E  neutrophils

A  macrophages

B  cytotoxic T cells

C  neutrophils

D  primary phagocytes

E  killer T cells

A  eosinophils

B  macrophages

C  platelets

D  mast cells

E  dendritic cells

A  Neutrophils

B  Lymphocytes

C  Eosinophils

D  Monocytes

E  Basophils

A  redness

B  swelling

C  pain

D  chills

E  warmth

A  antibodies

B  histamine

C  digestive enzymes

D  antigens

E  lysozyme

A  agranulocytes

B  granulocytes

C  monocytes

D  leukocytes

E  None of the choices are correct.

A  Cause a fever

B  Mobilize and attract immune components to injury site

C  Start tissue repair

D  Block further invasion

E  Destroy microbes

A  loss of blood due to hemorrhaging

B  production of white blood cells, red blood cells, and platelets

C  production of only red blood cells

D  migration of white blood cells from the blood out to the tissues

E  plugging of broken vessels to stop bleeding

A  hairs

B  tears

C  mucus

D  unbroken skin

E  T cells

A  is the liquid portion of blood in which blood cells are suspended

B  is mostly water

C  All of the choices are correct.

D  contains fibrinogen

E  contains albumin and globulins

A  None of these are mismatched.

B  Calor—warmth

C  Rubor—redness

D  Dolar—pain

E  Tumor—cancer

A  It can last hours to years.

B  Basophils and mast cells release histamine.

C  Serotonin causes smooth muscle contraction.

D  Fever could be beneficial to inhibiting the pathogen.

E  Pyrogens cause vasodilation and increased capillary permeability.

A  digestive tract

B  eyes

C  respiratory tract

D  skin

E  urinary tract

A  Lymphatic system

B  Intracellular fluid

C  Extracellular fluid

D  Bloodstream

A  Basophils; T cells

B  B cells; neutrophils

C  Monocytes; basophils

D  T cells; B cells

E  B cells; T cells

A  Develop from undifferentiated stem cells

B  Include Kupffer cells

C  Include erythrocytes that, when mature, lose their nuclei

D  After birth, produced in red bone marrow sites

E  Include leukocytes that are either granulocytes or agranulocytes

A  phagocytosis

B  chemotaxis

C  motility

D  vasodilation

E  diapedesis

A  lymph nodes

B  GALT

C  tonsils

D  thymus

E  spleen

A  Internal cellular and chemical defenses
Use of drugs and antibiotics
Host defenses due to B and T cells and their products

B  Host defenses due to B and T cells and their products
Use of drugs and antibiotics

C  Internal cellular and chemical defenses
Phagocytosis and inflammation
Anatomical and physiological barriers

D  Host defenses due to B and T cells and their products
Use of drugs and antibiotics
Anatomical and physiological barriers

A  is toxic to pathogens

B  None of the choices are correct.

C  creates a physical barrier against pathogens

D  physically restricts pathogens to a specific region

E  destroys pathogens