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Fresh Grad Lands Job as Real Estate Agent With Help from Professional Writers

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Manush’s story shows the importance of using powerful keywords to his resume in landing the job he wanted.

CNS Pharmacology

Navigation   » List of Schools  »  West Coast University  »  Pharmacy  »  Phar 642 – Principles of Drug Action  »  Spring 2022  »  CNS Pharmacology

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Below are the questions for the exam with the choices of answers:

Question #1
A 33-year-old female patient was prescribed a drug for schizophrenia that increases dopamine release in the mesocortical pathway while decreasing dopamine release in the mesolimbic system. What drug was the patient most likely prescribed?
A  Clozapine
B  Haloperidol
C  Quetiapine
D  Risperidone
Question #2
What is an example of a drug that prevents the conversion of L-DOPA to 3-o-methyldopa in the periphery?
A  Selegiline
B  Rotigotine
C  Carbidopa
D  Entacapone
Question #3
In patients, what symptom is an indication of toxicity from L-DOPA?
A  Bradykinesia
B  Hypokinesia
C  Akinesia
D  Dyskinesia
Question #4
A 24-year-old male patient that had been taking haloperidol for schizophrenia presented with gynecomastia. Decreased dopamine activity in what brain region most likely contributed to this adverse effect of haloperidol?
A  Tuberoinfundibular pathway
B  Mesocortical pathway
C  Mesolimbic pathway
D  Nigrostriatal pathway
E  Area postrema
Question #5
What is the impact of dopamine loss on the direct and indirect pathways of the basal ganglia in patients with Parkinson disease?
A  Activity is decreased in the direct pathway increased in the indirect pathway
B  Activity is increased in the direct pathway and decreased in the indirect pathway
C  Activity is increased in the direct and indirect pathways
D  Activity is decreased in the direct and indirect pathways
Question #6
What dopamine receptors are located in the basal ganglia and in the area postrema?
A  D3
B  D5
C  D4
D  D2
Question #7
What enzyme converts L-DOPA to dopamine?
A  Tyrosine hydroxylase
B  catechol-O-methyltransferase
C  DOPA decarboxylase
D  Monoamine oxidase
Question #8
What is an example of a NMDA receptor antagonist used for Alzheimer disease?
A  Memantine
B  Felbamate
C  Rufinamide
D  Ketamine
Question #9
What are the main clinical uses of etomidate and propofol?
A  Anesthesia
B  Insomnia
C  Seizures
D  Anxiety
Question #10
What is the overall effect of flumazenil on the actions of GABA at GABA-A receptors?
A  It activates GABA receptors
B  It has no effect on GABA activity
C  It increases GABA activity
D  It decreases GABA activity
Question #11
What happens to glutamate receptors when a patient has Alzheimer disease?
A  AMPA receptors become less sensitive
B  NMDA receptors become more sensitive
C  Presynaptic autoreceptors become hyperactive
D  GABA receptors become dysfunctional
Question #12
What is a potential result of increasing GABAergic input in the thalamocortical neurons of a patient who experiences absence seizures?
A  Increased frequency of seizures
B  No effect on absence seizures
C  Reduced frequency of seizures
Question #13
What is a step necessary for the activation of AMPA receptors?
A  Prolonged intense stimulation
B  Displacement of magnesium
C  Glutamate binding
D  Co-activation with glycine
Question #14
What is the most direct consequence of activating a GABA-B receptor?
A  Decreased activation of adenylyl cyclase
B  Influx of excitatory ions
C  Influx of inhibitor ions
D  Increased activity of protein kinase A
Question #15
What effect would a drug that inhibits the activity of glutamic acid decarboxylase have on amino acid neurotransmitter levels?
A  Glutamate would increase and GABA would increase
B  Glutamate would decrease and GABA would decrease
C  Glutamate would decrease and GABA would increase
D  Glutamate would increase and GABA would decrease
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Fresh Graduate
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