Lecture Exam 4 (Ch 12, 13, 14)

A  T-cell mediated

B  delayed

C  atopic

D  antibody mediated

E  systemic anaphylactic

A  fetal Rh + cells enter an Rh – mother

B  fetal Rh + cells enter an Rh + mother

C  fetal Rh ˗ cells enter an Rh + mother

D  maternal Rh + cells enter an Rh -fetus

E  maternal Rh ˗ cells enter an Rh + fetus

A  desensitization

B  hypersensitivity

C  immunodeficiency

D  transfusion reaction

E  autoimmune disease

A  humoralpathology

B  epidemiology

C  histopathology

D  immunopathology

E  hemopathology

A  IgM

B  complement

C  IgE

D  IgG

E  foreign cells

A  systemic lupus erythematosus

B  rheumatic fever

C  metastatic cancer

D  Graves’ disease

E  type I diabetes

A  hypograft

B  xenograft

C    

D  autograft

E  isograft

F  allograft

A  Contactant

B  None of the choices are correct.

C  Inhalant

D  Ingestant

E  Injectant

A  pruritus and headache

B  wheal and flare reaction in skin

C  increased sensitivity to pain

D  constriction of smooth muscle of bronchi and the intestine

E  relaxes vascular smooth muscle

A  type I, type II, and type III

B  type IV only

C  type I and type IV

D  type I only

E  type I, type II, type III, and type IV

A  autoantibodies and T cells

B  IgE and mast cells

C  a transfusion reaction

D  a deficiency in T-cell development

E  graft rejection

A  Rashes

B  Diarrhea

C  Rhinitis

D  Contact dermatitis

E  Sneezing

A  block synthesis of leukotrienes

B  reverse spasms of respiratory smooth muscles

C  inhibit the activity of lymphocytes

D  bind to histamine receptors on target organs

E  relieve inflammatory symptoms

A  Degranulation

B  Histamine acts on smooth muscle

C  Binding of IgE by the Fc region to mast cells and basophils

D  Prostaglandins cause vasodilation and increased vascular permeability

E  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

A  cells in thyroid follicles

B  acetylcholine receptors on smooth muscle

C  sodium pump proteins in the cell membrane

D  acetylcholine receptors on skeletal muscle

E  myelin sheath cells of the nervous system

A  Involves production of IgG and IgE antibodies

B  Antigen-antibody complexes are deposited in the basement membrane of epithelial tissues

C  Involves an immune complex reaction

D  The Arthus reaction is a local response

E  Serum sickness is a systemic response

A  anaphylaxis

B  atopic dermatitis

C  eczema

D  allergic rhinitis

E  asthma

A  Blood transfusion

B  Both skin graft and organ transplantation

C  All of thechoices are correct.

D  Organ transplantation

E  Skin graft

A  degranulation

B  None of thechoices are correct.

C  sensitization

D  desensitization

E  tissue matching

A  Degranulation

B  Histamine acts on smooth muscle

C  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

D  Binding of IgE by the Fc region to mast cells and basophils

E  Prostaglandins cause vasodilation and increased vascular permeability

A  Hypogammaglobulinemia

B  Formation of autoantibodies

C  Graft versus host disease

D  Host rejection of graft

E  None of the choices are correct.

A  Immune complex mediated

B  Both antibody mediated and immune complex mediated

C  Anaphylaxis

D  Antibody mediated

E  Both anaphylaxis and antibody mediated

A  rheumatoid arthritis

B  multiple sclerosis

C  Graves’ disease

D  tuberculin reaction

E  myasthenia gravis

A  histamine

B  prostaglandin

C  leukotriene

D  serotonin

E  platelet-activating factor

A  two identical light polypeptide chains

B  disulfide bonds between polypeptide chains

C  two identical heavy polypeptide chains

D  four antigen binding sites

E  a variable and constant region on each polypeptide chain

A  All of the choices are correct.

B  B cells maturing in bone marrow sites

C  T cells maturing in the thymus

D  hormonal signals that initiate development

E  release of mature lymphocytes to begin migration to various lymphoid organs

A  Fab

B  terminal

C  Fc

D  hinge

E  variable

A  directly destroy target cells

B  activate B cells and other T cells

C  secrete antibodies

D  function in allergic reactions

E  suppress immune reactions

A  include dendritic cells

B  hold and present processed antigen on their cell membrane surface

C  include macrophages

D  engulf and modify antigen to be more immunogenic

E  All of the choices are correct.

A  false

B  true

A    

B  typically a protein antigen

C  binding of T-cell to a site on the antigen

D  interleukin-1 activating the T helper cell

E  All of the choices are correct.

F  binding of T-cell to a class II MHC receptor on a macrophage

A  IgM

B  IgD

C  IgE

D  IgG

E  IgA

A  directly destroy target cells

B  secrete antibodies

C  function in allergic reactions

D  activate B cells and other T cells

E  suppress immune reactions

A  None of the choices are correct.

B  hapten

C  variable region

D  epitope

E  antigen binding site

A  are the result of genetic expression

B  aid in cellular development

C  All of the choices are correct.

D  receive and transmit chemical messages among other cells of the system

E  function in recognition of self molecules

A  have molecular complexity

B  are large molecules with a minimum molecular weight of 1,000

C  have large polymers made up of repeating subunits

D  are cells or large, complex molecules

E  are foreign to the immune system

A  heterophilic antigens

B  None of the choices are correct.

C  autoantigens

D  superantigens

E  allergens

A  helper T cells

B  cytotoxic T cells

C  suppressor T cells

D  natural killer (NK) cells

E  delayed hypersensitivity T cells

A  Cytotoxic T cells

B  Helper T cells

C  Plasma cells

D  B cells

E  Antigen-presenting cells

A  all HLA antigens

B  self receptors recognized by T lymphocytes

C  certain secreted complement components

D  receptors located primarily on macrophages and B cells

E  All of the choices are correct.

A  true

B  false

A  contains a central J chain

B  is a dimer

C  has 10 antigen binding sites

D  can serve as a B-cell receptor

E  is the first class synthesized by a plasma cell

A  bacterial toxins that activate T cells at a 100 times greater rate than other antigens

B  those that evoke allergic reactions

C  None of the choices are correct.

D  body tissues that the immune system mistakes as foreign

E  cell markers found in some member of a species but not in other members

A  true

B  false

A  IgE

B  IgM

C  IgA

D  IgD

E  IgG

A  have membrane receptors that recognize foreign antigens

B  gain tolerance to self by destruction of lymphocytes that could react against self

C  possess MHC antigens for recognizing self

D  develop into clones of B and T cells with extreme variations of specificity

E  All of the choices are correct.

A  a set of genes that code for MHC glycoproteins

B  All of the choices are correct.

C  glycoproteins, called MHC antigens, found on all body cells

D    

E  found on the third chromosome

F  located in the thymus gland

A  red blood cells

B  eosinophils

C  epithelial cells

D  islet of Langerhans cells

E  leukocytes

A  IgG only

B  IgD only

C  IgM only

D  IgM and IgD

E  IgD and IgE

A  Eyes

B  Respiratory tract

C  Skin

D  Digestive tract

E  Urinary tract

A  increases metabolism

B  increases phagocytosis

C  increases the availability of iron

D  stimulates hematopoiesis

E  reduces the ability of temperature-sensitive organisms to multiply

A  Includes chemicals such as lysozyme and lactic acid
Involves barriers at portals of entry
Examples include the ciliated epithelium of the respiratory passages, excretion of urine, and production of tears

B  Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

C  Includes chemicals such as lysozyme and lactic acid
Involves recognition of foreign agents by their pathogen-associated molecular patterns

D  Involves barriers at portals of entry
Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

A  neutrophils

B  eosinophils

C  monocytes

D  lymphocytes

E  basophils

A  primary phagocytes

B  cytotoxic T cells

C  macrophages

D  neutrophils

E  killer T cells

A  dendritic cells

B  eosinophils

C  platelets

D  mast cells

E  macrophages

A  Lymphocytes

B  Neutrophils

C  Eosinophils

D  Monocytes

E  Basophils

A  swelling

B  pain

C  chills

D  warmth

E  redness

A  antibodies

B  histamine

C  antigens

D  lysozyme

E  digestive enzymes

A  leukocytes

B  agranulocytes

C  monocytes

D  None of the choices are correct.

E  granulocytes

A  Mobilize and attract immune components to injury site

B  Start tissue repair

C  Destroy microbes

D  Cause a fever

E  Block further invasion

A  loss of blood due to hemorrhaging

B  production of only red blood cells

C  plugging of broken vessels to stop bleeding

D  production of white blood cells, red blood cells, and platelets

E  migration of white blood cells from the blood out to the tissues

A  tears

B  unbroken skin

C  hairs

D  mucus

E  T cells

A  contains fibrinogen

B  is mostly water

C  contains albumin and globulins

D  is the liquid portion of blood in which blood cells are suspended

E  All of the choices are correct.

A  Dolar—pain

B  Tumor—cancer

C  None of these are mismatched.

D  Calor—warmth

E  Rubor—redness

A  Basophils and mast cells release histamine.

B  It can last hours to years.

C  Pyrogens cause vasodilation and increased capillary permeability.

D  Serotonin causes smooth muscle contraction.

E  Fever could be beneficial to inhibiting the pathogen.

A  respiratory tract

B  urinary tract

C  skin

D  digestive tract

E  eyes

A  Lymphatic system

B  Intracellular fluid

C  Extracellular fluid

D  Bloodstream

A  B cells; T cells

B  Basophils; T cells

C  Monocytes; basophils

D  T cells; B cells

E  B cells; neutrophils

A  Include leukocytes that are either granulocytes or agranulocytes

B  Include Kupffer cells

C  Include erythrocytes that, when mature, lose their nuclei

D  Develop from undifferentiated stem cells

E  After birth, produced in red bone marrow sites

A  phagocytosis

B  chemotaxis

C  motility

D  diapedesis

E  vasodilation

A  lymph nodes

B  GALT

C  tonsils

D  thymus

E  spleen

A  Internal cellular and chemical defenses
Phagocytosis and inflammation
Anatomical and physiological barriers

B  Host defenses due to B and T cells and their products
Use of drugs and antibiotics
Anatomical and physiological barriers

C  Internal cellular and chemical defenses
Use of drugs and antibiotics
Host defenses due to B and T cells and their products

D  Host defenses due to B and T cells and their products
Use of drugs and antibiotics

A  None of the choices are correct.

B  is toxic to pathogens

C  destroys pathogens

D  creates a physical barrier against pathogens

E  physically restricts pathogens to a specific region