Lecture Exam 4 (Ch 12, 13, 14)

A  systemic anaphylactic

B  T-cell mediated

C  delayed

D  atopic

E  antibody mediated

A  maternal Rh + cells enter an Rh -fetus

B  fetal Rh + cells enter an Rh + mother

C  maternal Rh ˗ cells enter an Rh + fetus

D  fetal Rh ˗ cells enter an Rh + mother

E  fetal Rh + cells enter an Rh – mother

A  hypersensitivity

B  autoimmune disease

C  immunodeficiency

D  transfusion reaction

E  desensitization

A  humoralpathology

B  epidemiology

C  hemopathology

D  histopathology

E  immunopathology

A  IgE

B  IgM

C  foreign cells

D  complement

E  IgG

A  metastatic cancer

B  Graves’ disease

C  rheumatic fever

D  type I diabetes

E  systemic lupus erythematosus

A  hypograft

B  xenograft

C  isograft

D  autograft

E  allograft

F    

A  None of the choices are correct.

B  Contactant

C  Injectant

D  Ingestant

E  Inhalant

A  relaxes vascular smooth muscle

B  wheal and flare reaction in skin

C  constriction of smooth muscle of bronchi and the intestine

D  increased sensitivity to pain

E  pruritus and headache

A  type I, type II, type III, and type IV

B  type I, type II, and type III

C  type I and type IV

D  type I only

E  type IV only

A  a deficiency in T-cell development

B  graft rejection

C  IgE and mast cells

D  autoantibodies and T cells

E  a transfusion reaction

A  Sneezing

B  Diarrhea

C  Rhinitis

D  Contact dermatitis

E  Rashes

A  bind to histamine receptors on target organs

B  reverse spasms of respiratory smooth muscles

C  block synthesis of leukotrienes

D  relieve inflammatory symptoms

E  inhibit the activity of lymphocytes

A  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

B  Degranulation

C  Binding of IgE by the Fc region to mast cells and basophils

D  Prostaglandins cause vasodilation and increased vascular permeability

E  Histamine acts on smooth muscle

A  cells in thyroid follicles

B  myelin sheath cells of the nervous system

C  acetylcholine receptors on smooth muscle

D  acetylcholine receptors on skeletal muscle

E  sodium pump proteins in the cell membrane

A  Involves an immune complex reaction

B  Antigen-antibody complexes are deposited in the basement membrane of epithelial tissues

C  The Arthus reaction is a local response

D  Serum sickness is a systemic response

E  Involves production of IgG and IgE antibodies

A  asthma

B  anaphylaxis

C  allergic rhinitis

D  atopic dermatitis

E  eczema

A  Both skin graft and organ transplantation

B  All of thechoices are correct.

C  Organ transplantation

D  Blood transfusion

E  Skin graft

A  sensitization

B  degranulation

C  None of thechoices are correct.

D  tissue matching

E  desensitization

A  Degranulation

B  Histamine acts on smooth muscle

C  Prostaglandins cause vasodilation and increased vascular permeability

D  Binding of IgE by the Fc region to mast cells and basophils

E  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

A  Graft versus host disease

B  Formation of autoantibodies

C  Host rejection of graft

D  None of the choices are correct.

E  Hypogammaglobulinemia

A  Antibody mediated

B  Both antibody mediated and immune complex mediated

C  Immune complex mediated

D  Anaphylaxis

E  Both anaphylaxis and antibody mediated

A  rheumatoid arthritis

B  myasthenia gravis

C  multiple sclerosis

D  Graves’ disease

E  tuberculin reaction

A  platelet-activating factor

B  serotonin

C  leukotriene

D  prostaglandin

E  histamine

A  disulfide bonds between polypeptide chains

B  two identical light polypeptide chains

C  two identical heavy polypeptide chains

D  four antigen binding sites

E  a variable and constant region on each polypeptide chain

A  T cells maturing in the thymus

B  hormonal signals that initiate development

C  B cells maturing in bone marrow sites

D  All of the choices are correct.

E  release of mature lymphocytes to begin migration to various lymphoid organs

A  hinge

B  variable

C  Fc

D  terminal

E  Fab

A  function in allergic reactions

B  activate B cells and other T cells

C  secrete antibodies

D  suppress immune reactions

E  directly destroy target cells

A  hold and present processed antigen on their cell membrane surface

B  All of the choices are correct.

C  include dendritic cells

D  engulf and modify antigen to be more immunogenic

E  include macrophages

A  true

B  false

A  binding of T-cell to a site on the antigen

B  All of the choices are correct.

C    

D  binding of T-cell to a class II MHC receptor on a macrophage

E  interleukin-1 activating the T helper cell

F  typically a protein antigen

A  IgE

B  IgG

C  IgD

D  IgA

E  IgM

A  function in allergic reactions

B  secrete antibodies

C  suppress immune reactions

D  activate B cells and other T cells

E  directly destroy target cells

A  epitope

B  antigen binding site

C  hapten

D  None of the choices are correct.

E  variable region

A  receive and transmit chemical messages among other cells of the system

B  All of the choices are correct.

C  function in recognition of self molecules

D  are the result of genetic expression

E  aid in cellular development

A  are cells or large, complex molecules

B  have molecular complexity

C  are foreign to the immune system

D  have large polymers made up of repeating subunits

E  are large molecules with a minimum molecular weight of 1,000

A  autoantigens

B  heterophilic antigens

C  superantigens

D  allergens

E  None of the choices are correct.

A  cytotoxic T cells

B  helper T cells

C  suppressor T cells

D  natural killer (NK) cells

E  delayed hypersensitivity T cells

A  Antigen-presenting cells

B  Helper T cells

C  B cells

D  Cytotoxic T cells

E  Plasma cells

A  all HLA antigens

B  All of the choices are correct.

C  self receptors recognized by T lymphocytes

D  receptors located primarily on macrophages and B cells

E  certain secreted complement components

A  false

B  true

A  is a dimer

B  has 10 antigen binding sites

C  is the first class synthesized by a plasma cell

D  can serve as a B-cell receptor

E  contains a central J chain

A  None of the choices are correct.

B  bacterial toxins that activate T cells at a 100 times greater rate than other antigens

C  body tissues that the immune system mistakes as foreign

D  cell markers found in some member of a species but not in other members

E  those that evoke allergic reactions

A  true

B  false

A  IgE

B  IgG

C  IgD

D  IgM

E  IgA

A  develop into clones of B and T cells with extreme variations of specificity

B  have membrane receptors that recognize foreign antigens

C  possess MHC antigens for recognizing self

D  gain tolerance to self by destruction of lymphocytes that could react against self

E  All of the choices are correct.

A    

B  glycoproteins, called MHC antigens, found on all body cells

C  found on the third chromosome

D  located in the thymus gland

E  a set of genes that code for MHC glycoproteins

F  All of the choices are correct.

A  epithelial cells

B  islet of Langerhans cells

C  red blood cells

D  eosinophils

E  leukocytes

A  IgD and IgE

B  IgM only

C  IgM and IgD

D  IgD only

E  IgG only

A  Skin

B  Respiratory tract

C  Digestive tract

D  Urinary tract

E  Eyes

A  reduces the ability of temperature-sensitive organisms to multiply

B  increases the availability of iron

C  stimulates hematopoiesis

D  increases phagocytosis

E  increases metabolism

A  Involves barriers at portals of entry
Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

B  Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

C  Includes chemicals such as lysozyme and lactic acid
Involves recognition of foreign agents by their pathogen-associated molecular patterns

D  Includes chemicals such as lysozyme and lactic acid
Involves barriers at portals of entry
Examples include the ciliated epithelium of the respiratory passages, excretion of urine, and production of tears

A  monocytes

B  neutrophils

C  eosinophils

D  basophils

E  lymphocytes

A  primary phagocytes

B  cytotoxic T cells

C  neutrophils

D  macrophages

E  killer T cells

A  macrophages

B  mast cells

C  eosinophils

D  platelets

E  dendritic cells

A  Neutrophils

B  Monocytes

C  Lymphocytes

D  Eosinophils

E  Basophils

A  redness

B  pain

C  swelling

D  warmth

E  chills

A  digestive enzymes

B  antigens

C  antibodies

D  histamine

E  lysozyme

A  leukocytes

B  agranulocytes

C  None of the choices are correct.

D  granulocytes

E  monocytes

A  Block further invasion

B  Cause a fever

C  Mobilize and attract immune components to injury site

D  Start tissue repair

E  Destroy microbes

A  migration of white blood cells from the blood out to the tissues

B  loss of blood due to hemorrhaging

C  production of only red blood cells

D  production of white blood cells, red blood cells, and platelets

E  plugging of broken vessels to stop bleeding

A  T cells

B  tears

C  hairs

D  unbroken skin

E  mucus

A  contains albumin and globulins

B  All of the choices are correct.

C  is mostly water

D  contains fibrinogen

E  is the liquid portion of blood in which blood cells are suspended

A  Dolar—pain

B  Calor—warmth

C  Tumor—cancer

D  Rubor—redness

E  None of these are mismatched.

A  Basophils and mast cells release histamine.

B  Serotonin causes smooth muscle contraction.

C  Pyrogens cause vasodilation and increased capillary permeability.

D  Fever could be beneficial to inhibiting the pathogen.

E  It can last hours to years.

A  skin

B  respiratory tract

C  eyes

D  digestive tract

E  urinary tract

A  Intracellular fluid

B  Extracellular fluid

C  Lymphatic system

D  Bloodstream

A  Basophils; T cells

B  B cells; neutrophils

C  B cells; T cells

D  Monocytes; basophils

E  T cells; B cells

A  Include Kupffer cells

B  Include leukocytes that are either granulocytes or agranulocytes

C  Develop from undifferentiated stem cells

D  After birth, produced in red bone marrow sites

E  Include erythrocytes that, when mature, lose their nuclei

A  diapedesis

B  motility

C  phagocytosis

D  vasodilation

E  chemotaxis

A  GALT

B  spleen

C  lymph nodes

D  tonsils

E  thymus

A  Internal cellular and chemical defenses
Use of drugs and antibiotics
Host defenses due to B and T cells and their products

B  Host defenses due to B and T cells and their products
Use of drugs and antibiotics

C  Internal cellular and chemical defenses
Phagocytosis and inflammation
Anatomical and physiological barriers

D  Host defenses due to B and T cells and their products
Use of drugs and antibiotics
Anatomical and physiological barriers

A  physically restricts pathogens to a specific region

B  destroys pathogens

C  creates a physical barrier against pathogens

D  is toxic to pathogens

E  None of the choices are correct.