Lecture Exam 4 (Ch 12, 13, 14)

A  antibody mediated

B  T-cell mediated

C  systemic anaphylactic

D  atopic

E  delayed

A  maternal Rh ˗ cells enter an Rh + fetus

B  maternal Rh + cells enter an Rh -fetus

C  fetal Rh + cells enter an Rh + mother

D  fetal Rh ˗ cells enter an Rh + mother

E  fetal Rh + cells enter an Rh – mother

A  desensitization

B  immunodeficiency

C  autoimmune disease

D  hypersensitivity

E  transfusion reaction

A  histopathology

B  hemopathology

C  humoralpathology

D  epidemiology

E  immunopathology

A  IgE

B  IgM

C  IgG

D  complement

E  foreign cells

A  rheumatic fever

B  type I diabetes

C  systemic lupus erythematosus

D  Graves’ disease

E  metastatic cancer

A  autograft

B  allograft

C  hypograft

D    

E  xenograft

F  isograft

A  Injectant

B  Contactant

C  Inhalant

D  Ingestant

E  None of the choices are correct.

A  relaxes vascular smooth muscle

B  wheal and flare reaction in skin

C  increased sensitivity to pain

D  constriction of smooth muscle of bronchi and the intestine

E  pruritus and headache

A  type IV only

B  type I only

C  type I, type II, type III, and type IV

D  type I, type II, and type III

E  type I and type IV

A  IgE and mast cells

B  graft rejection

C  a transfusion reaction

D  autoantibodies and T cells

E  a deficiency in T-cell development

A  Rashes

B  Sneezing

C  Diarrhea

D  Contact dermatitis

E  Rhinitis

A  inhibit the activity of lymphocytes

B  bind to histamine receptors on target organs

C  relieve inflammatory symptoms

D  reverse spasms of respiratory smooth muscles

E  block synthesis of leukotrienes

A  Histamine acts on smooth muscle

B  Binding of IgE by the Fc region to mast cells and basophils

C  Prostaglandins cause vasodilation and increased vascular permeability

D  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

E  Degranulation

A  cells in thyroid follicles

B  acetylcholine receptors on skeletal muscle

C  sodium pump proteins in the cell membrane

D  acetylcholine receptors on smooth muscle

E  myelin sheath cells of the nervous system

A  Involves an immune complex reaction

B  Involves production of IgG and IgE antibodies

C  Antigen-antibody complexes are deposited in the basement membrane of epithelial tissues

D  The Arthus reaction is a local response

E  Serum sickness is a systemic response

A  asthma

B  atopic dermatitis

C  allergic rhinitis

D  anaphylaxis

E  eczema

A  Organ transplantation

B  Both skin graft and organ transplantation

C  Skin graft

D  All of thechoices are correct.

E  Blood transfusion

A  desensitization

B  None of thechoices are correct.

C  degranulation

D  sensitization

E  tissue matching

A  Binding of IgE by the Fc region to mast cells and basophils

B  Degranulation

C  Histamine acts on smooth muscle

D  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

E  Prostaglandins cause vasodilation and increased vascular permeability

A  Graft versus host disease

B  None of the choices are correct.

C  Hypogammaglobulinemia

D  Formation of autoantibodies

E  Host rejection of graft

A  Antibody mediated

B  Anaphylaxis

C  Both antibody mediated and immune complex mediated

D  Immune complex mediated

E  Both anaphylaxis and antibody mediated

A  Graves’ disease

B  rheumatoid arthritis

C  myasthenia gravis

D  multiple sclerosis

E  tuberculin reaction

A  leukotriene

B  prostaglandin

C  histamine

D  platelet-activating factor

E  serotonin

A  two identical heavy polypeptide chains

B  a variable and constant region on each polypeptide chain

C  four antigen binding sites

D  disulfide bonds between polypeptide chains

E  two identical light polypeptide chains

A  hormonal signals that initiate development

B  All of the choices are correct.

C  release of mature lymphocytes to begin migration to various lymphoid organs

D  T cells maturing in the thymus

E  B cells maturing in bone marrow sites

A  hinge

B  terminal

C  Fab

D  Fc

E  variable

A  secrete antibodies

B  activate B cells and other T cells

C  function in allergic reactions

D  directly destroy target cells

E  suppress immune reactions

A  include macrophages

B  hold and present processed antigen on their cell membrane surface

C  All of the choices are correct.

D  engulf and modify antigen to be more immunogenic

E  include dendritic cells

A  false

B  true

A  typically a protein antigen

B  interleukin-1 activating the T helper cell

C  binding of T-cell to a class II MHC receptor on a macrophage

D  binding of T-cell to a site on the antigen

E    

F  All of the choices are correct.

A  IgG

B  IgE

C  IgM

D  IgD

E  IgA

A  function in allergic reactions

B  directly destroy target cells

C  suppress immune reactions

D  activate B cells and other T cells

E  secrete antibodies

A  antigen binding site

B  None of the choices are correct.

C  hapten

D  variable region

E  epitope

A  All of the choices are correct.

B  receive and transmit chemical messages among other cells of the system

C  aid in cellular development

D  are the result of genetic expression

E  function in recognition of self molecules

A  are large molecules with a minimum molecular weight of 1,000

B  have large polymers made up of repeating subunits

C  have molecular complexity

D  are foreign to the immune system

E  are cells or large, complex molecules

A  allergens

B  autoantigens

C  heterophilic antigens

D  None of the choices are correct.

E  superantigens

A  suppressor T cells

B  delayed hypersensitivity T cells

C  natural killer (NK) cells

D  cytotoxic T cells

E  helper T cells

A  Antigen-presenting cells

B  B cells

C  Helper T cells

D  Cytotoxic T cells

E  Plasma cells

A  self receptors recognized by T lymphocytes

B  all HLA antigens

C  certain secreted complement components

D  receptors located primarily on macrophages and B cells

E  All of the choices are correct.

A  false

B  true

A  is the first class synthesized by a plasma cell

B  can serve as a B-cell receptor

C  has 10 antigen binding sites

D  is a dimer

E  contains a central J chain

A  those that evoke allergic reactions

B  None of the choices are correct.

C  cell markers found in some member of a species but not in other members

D  body tissues that the immune system mistakes as foreign

E  bacterial toxins that activate T cells at a 100 times greater rate than other antigens

A  false

B  true

A  IgM

B  IgD

C  IgA

D  IgG

E  IgE

A  have membrane receptors that recognize foreign antigens

B  gain tolerance to self by destruction of lymphocytes that could react against self

C  develop into clones of B and T cells with extreme variations of specificity

D  All of the choices are correct.

E  possess MHC antigens for recognizing self

A  found on the third chromosome

B  a set of genes that code for MHC glycoproteins

C  All of the choices are correct.

D  located in the thymus gland

E    

F  glycoproteins, called MHC antigens, found on all body cells

A  eosinophils

B  islet of Langerhans cells

C  red blood cells

D  epithelial cells

E  leukocytes

A  IgD and IgE

B  IgD only

C  IgM and IgD

D  IgM only

E  IgG only

A  Eyes

B  Digestive tract

C  Urinary tract

D  Respiratory tract

E  Skin

A  increases phagocytosis

B  reduces the ability of temperature-sensitive organisms to multiply

C  increases the availability of iron

D  increases metabolism

E  stimulates hematopoiesis

A  Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

B  Includes chemicals such as lysozyme and lactic acid
Involves recognition of foreign agents by their pathogen-associated molecular patterns

C  Includes chemicals such as lysozyme and lactic acid
Involves barriers at portals of entry
Examples include the ciliated epithelium of the respiratory passages, excretion of urine, and production of tears

D  Involves barriers at portals of entry
Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

A  lymphocytes

B  monocytes

C  basophils

D  neutrophils

E  eosinophils

A  macrophages

B  primary phagocytes

C  killer T cells

D  neutrophils

E  cytotoxic T cells

A  dendritic cells

B  macrophages

C  mast cells

D  platelets

E  eosinophils

A  Basophils

B  Lymphocytes

C  Eosinophils

D  Neutrophils

E  Monocytes

A  swelling

B  warmth

C  chills

D  pain

E  redness

A  antigens

B  histamine

C  digestive enzymes

D  antibodies

E  lysozyme

A  leukocytes

B  granulocytes

C  agranulocytes

D  monocytes

E  None of the choices are correct.

A  Block further invasion

B  Mobilize and attract immune components to injury site

C  Start tissue repair

D  Destroy microbes

E  Cause a fever

A  loss of blood due to hemorrhaging

B  production of only red blood cells

C  migration of white blood cells from the blood out to the tissues

D  plugging of broken vessels to stop bleeding

E  production of white blood cells, red blood cells, and platelets

A  T cells

B  tears

C  unbroken skin

D  hairs

E  mucus

A  contains fibrinogen

B  All of the choices are correct.

C  is mostly water

D  is the liquid portion of blood in which blood cells are suspended

E  contains albumin and globulins

A  None of these are mismatched.

B  Calor—warmth

C  Rubor—redness

D  Dolar—pain

E  Tumor—cancer

A  Fever could be beneficial to inhibiting the pathogen.

B  Pyrogens cause vasodilation and increased capillary permeability.

C  It can last hours to years.

D  Basophils and mast cells release histamine.

E  Serotonin causes smooth muscle contraction.

A  urinary tract

B  skin

C  respiratory tract

D  digestive tract

E  eyes

A  Lymphatic system

B  Bloodstream

C  Extracellular fluid

D  Intracellular fluid

A  T cells; B cells

B  B cells; neutrophils

C  Monocytes; basophils

D  B cells; T cells

E  Basophils; T cells

A  Include Kupffer cells

B  Develop from undifferentiated stem cells

C  Include leukocytes that are either granulocytes or agranulocytes

D  After birth, produced in red bone marrow sites

E  Include erythrocytes that, when mature, lose their nuclei

A  vasodilation

B  chemotaxis

C  phagocytosis

D  motility

E  diapedesis

A  spleen

B  thymus

C  lymph nodes

D  GALT

E  tonsils

A  Host defenses due to B and T cells and their products
Use of drugs and antibiotics
Anatomical and physiological barriers

B  Host defenses due to B and T cells and their products
Use of drugs and antibiotics

C  Internal cellular and chemical defenses
Phagocytosis and inflammation
Anatomical and physiological barriers

D  Internal cellular and chemical defenses
Use of drugs and antibiotics
Host defenses due to B and T cells and their products

A  creates a physical barrier against pathogens

B  destroys pathogens

C  is toxic to pathogens

D  None of the choices are correct.

E  physically restricts pathogens to a specific region