Lecture Exam 4 (Ch 12, 13, 14)

A  T-cell mediated

B  delayed

C  systemic anaphylactic

D  atopic

E  antibody mediated

A  fetal Rh + cells enter an Rh – mother

B  fetal Rh ˗ cells enter an Rh + mother

C  maternal Rh + cells enter an Rh -fetus

D  maternal Rh ˗ cells enter an Rh + fetus

E  fetal Rh + cells enter an Rh + mother

A  desensitization

B  autoimmune disease

C  transfusion reaction

D  immunodeficiency

E  hypersensitivity

A  histopathology

B  hemopathology

C  humoralpathology

D  immunopathology

E  epidemiology

A  IgE

B  IgM

C  complement

D  foreign cells

E  IgG

A  systemic lupus erythematosus

B  rheumatic fever

C  Graves’ disease

D  type I diabetes

E  metastatic cancer

A  autograft

B  hypograft

C  xenograft

D  isograft

E  allograft

F    

A  Injectant

B  Contactant

C  Ingestant

D  None of the choices are correct.

E  Inhalant

A  relaxes vascular smooth muscle

B  wheal and flare reaction in skin

C  constriction of smooth muscle of bronchi and the intestine

D  pruritus and headache

E  increased sensitivity to pain

A  type I and type IV

B  type I, type II, and type III

C  type I, type II, type III, and type IV

D  type I only

E  type IV only

A  a deficiency in T-cell development

B  graft rejection

C  IgE and mast cells

D  autoantibodies and T cells

E  a transfusion reaction

A  Rhinitis

B  Sneezing

C  Diarrhea

D  Rashes

E  Contact dermatitis

A  reverse spasms of respiratory smooth muscles

B  relieve inflammatory symptoms

C  block synthesis of leukotrienes

D  bind to histamine receptors on target organs

E  inhibit the activity of lymphocytes

A  Degranulation

B  Prostaglandins cause vasodilation and increased vascular permeability

C  Histamine acts on smooth muscle

D  Binding of IgE by the Fc region to mast cells and basophils

E  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

A  myelin sheath cells of the nervous system

B  acetylcholine receptors on skeletal muscle

C  acetylcholine receptors on smooth muscle

D  sodium pump proteins in the cell membrane

E  cells in thyroid follicles

A  Serum sickness is a systemic response

B  The Arthus reaction is a local response

C  Involves an immune complex reaction

D  Involves production of IgG and IgE antibodies

E  Antigen-antibody complexes are deposited in the basement membrane of epithelial tissues

A  allergic rhinitis

B  atopic dermatitis

C  anaphylaxis

D  eczema

E  asthma

A  Blood transfusion

B  Organ transplantation

C  Skin graft

D  All of thechoices are correct.

E  Both skin graft and organ transplantation

A  None of thechoices are correct.

B  sensitization

C  tissue matching

D  desensitization

E  degranulation

A  Prostaglandins cause vasodilation and increased vascular permeability

B  Histamine acts on smooth muscle

C  Binding of IgE by the Fc region to mast cells and basophils

D  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

E  Degranulation

A  Formation of autoantibodies

B  Hypogammaglobulinemia

C  Graft versus host disease

D  Host rejection of graft

E  None of the choices are correct.

A  Anaphylaxis

B  Both antibody mediated and immune complex mediated

C  Both anaphylaxis and antibody mediated

D  Antibody mediated

E  Immune complex mediated

A  tuberculin reaction

B  Graves’ disease

C  rheumatoid arthritis

D  multiple sclerosis

E  myasthenia gravis

A  serotonin

B  histamine

C  prostaglandin

D  leukotriene

E  platelet-activating factor

A  two identical heavy polypeptide chains

B  a variable and constant region on each polypeptide chain

C  disulfide bonds between polypeptide chains

D  four antigen binding sites

E  two identical light polypeptide chains

A  release of mature lymphocytes to begin migration to various lymphoid organs

B  T cells maturing in the thymus

C  hormonal signals that initiate development

D  B cells maturing in bone marrow sites

E  All of the choices are correct.

A  terminal

B  Fab

C  Fc

D  hinge

E  variable

A  suppress immune reactions

B  secrete antibodies

C  activate B cells and other T cells

D  directly destroy target cells

E  function in allergic reactions

A  include dendritic cells

B  All of the choices are correct.

C  engulf and modify antigen to be more immunogenic

D  hold and present processed antigen on their cell membrane surface

E  include macrophages

A  true

B  false

A  All of the choices are correct.

B  typically a protein antigen

C    

D  binding of T-cell to a site on the antigen

E  binding of T-cell to a class II MHC receptor on a macrophage

F  interleukin-1 activating the T helper cell

A  IgA

B  IgG

C  IgM

D  IgD

E  IgE

A  activate B cells and other T cells

B  suppress immune reactions

C  function in allergic reactions

D  directly destroy target cells

E  secrete antibodies

A  antigen binding site

B  None of the choices are correct.

C  hapten

D  epitope

E  variable region

A  All of the choices are correct.

B  receive and transmit chemical messages among other cells of the system

C  function in recognition of self molecules

D  aid in cellular development

E  are the result of genetic expression

A  are foreign to the immune system

B  have large polymers made up of repeating subunits

C  are large molecules with a minimum molecular weight of 1,000

D  are cells or large, complex molecules

E  have molecular complexity

A  None of the choices are correct.

B  superantigens

C  allergens

D  autoantigens

E  heterophilic antigens

A  suppressor T cells

B  helper T cells

C  cytotoxic T cells

D  delayed hypersensitivity T cells

E  natural killer (NK) cells

A  Helper T cells

B  Plasma cells

C  Antigen-presenting cells

D  Cytotoxic T cells

E  B cells

A  All of the choices are correct.

B  receptors located primarily on macrophages and B cells

C  all HLA antigens

D  certain secreted complement components

E  self receptors recognized by T lymphocytes

A  false

B  true

A  can serve as a B-cell receptor

B  is the first class synthesized by a plasma cell

C  has 10 antigen binding sites

D  contains a central J chain

E  is a dimer

A  body tissues that the immune system mistakes as foreign

B  cell markers found in some member of a species but not in other members

C  those that evoke allergic reactions

D  None of the choices are correct.

E  bacterial toxins that activate T cells at a 100 times greater rate than other antigens

A  false

B  true

A  IgG

B  IgE

C  IgM

D  IgD

E  IgA

A  gain tolerance to self by destruction of lymphocytes that could react against self

B  possess MHC antigens for recognizing self

C  develop into clones of B and T cells with extreme variations of specificity

D  have membrane receptors that recognize foreign antigens

E  All of the choices are correct.

A  a set of genes that code for MHC glycoproteins

B  found on the third chromosome

C  All of the choices are correct.

D    

E  glycoproteins, called MHC antigens, found on all body cells

F  located in the thymus gland

A  islet of Langerhans cells

B  leukocytes

C  eosinophils

D  red blood cells

E  epithelial cells

A  IgD only

B  IgM only

C  IgD and IgE

D  IgM and IgD

E  IgG only

A  Eyes

B  Respiratory tract

C  Digestive tract

D  Skin

E  Urinary tract

A  reduces the ability of temperature-sensitive organisms to multiply

B  stimulates hematopoiesis

C  increases the availability of iron

D  increases metabolism

E  increases phagocytosis

A  Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

B  Includes chemicals such as lysozyme and lactic acid
Involves barriers at portals of entry
Examples include the ciliated epithelium of the respiratory passages, excretion of urine, and production of tears

C  Involves barriers at portals of entry
Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

D  Includes chemicals such as lysozyme and lactic acid
Involves recognition of foreign agents by their pathogen-associated molecular patterns

A  basophils

B  neutrophils

C  eosinophils

D  monocytes

E  lymphocytes

A  killer T cells

B  macrophages

C  cytotoxic T cells

D  primary phagocytes

E  neutrophils

A  platelets

B  dendritic cells

C  mast cells

D  eosinophils

E  macrophages

A  Neutrophils

B  Lymphocytes

C  Basophils

D  Eosinophils

E  Monocytes

A  warmth

B  pain

C  chills

D  redness

E  swelling

A  histamine

B  digestive enzymes

C  antigens

D  lysozyme

E  antibodies

A  None of the choices are correct.

B  granulocytes

C  leukocytes

D  monocytes

E  agranulocytes

A  Block further invasion

B  Cause a fever

C  Destroy microbes

D  Start tissue repair

E  Mobilize and attract immune components to injury site

A  plugging of broken vessels to stop bleeding

B  migration of white blood cells from the blood out to the tissues

C  production of white blood cells, red blood cells, and platelets

D  loss of blood due to hemorrhaging

E  production of only red blood cells

A  unbroken skin

B  hairs

C  tears

D  mucus

E  T cells

A  is the liquid portion of blood in which blood cells are suspended

B  contains albumin and globulins

C  is mostly water

D  contains fibrinogen

E  All of the choices are correct.

A  Calor—warmth

B  None of these are mismatched.

C  Tumor—cancer

D  Dolar—pain

E  Rubor—redness

A  Serotonin causes smooth muscle contraction.

B  Pyrogens cause vasodilation and increased capillary permeability.

C  Fever could be beneficial to inhibiting the pathogen.

D  Basophils and mast cells release histamine.

E  It can last hours to years.

A  urinary tract

B  digestive tract

C  eyes

D  skin

E  respiratory tract

A  Bloodstream

B  Lymphatic system

C  Intracellular fluid

D  Extracellular fluid

A  B cells; neutrophils

B  T cells; B cells

C  B cells; T cells

D  Monocytes; basophils

E  Basophils; T cells

A  Include leukocytes that are either granulocytes or agranulocytes

B  Include erythrocytes that, when mature, lose their nuclei

C  After birth, produced in red bone marrow sites

D  Develop from undifferentiated stem cells

E  Include Kupffer cells

A  phagocytosis

B  vasodilation

C  chemotaxis

D  diapedesis

E  motility

A  GALT

B  thymus

C  tonsils

D  spleen

E  lymph nodes

A  Host defenses due to B and T cells and their products
Use of drugs and antibiotics

B  Host defenses due to B and T cells and their products
Use of drugs and antibiotics
Anatomical and physiological barriers

C  Internal cellular and chemical defenses
Use of drugs and antibiotics
Host defenses due to B and T cells and their products

D  Internal cellular and chemical defenses
Phagocytosis and inflammation
Anatomical and physiological barriers

A  physically restricts pathogens to a specific region

B  is toxic to pathogens

C  creates a physical barrier against pathogens

D  None of the choices are correct.

E  destroys pathogens