Lecture Exam 4 (Ch 12, 13, 14)

A  antibody mediated

B  delayed

C  T-cell mediated

D  atopic

E  systemic anaphylactic

A  fetal Rh + cells enter an Rh + mother

B  fetal Rh ˗ cells enter an Rh + mother

C  fetal Rh + cells enter an Rh – mother

D  maternal Rh ˗ cells enter an Rh + fetus

E  maternal Rh + cells enter an Rh -fetus

A  immunodeficiency

B  autoimmune disease

C  transfusion reaction

D  desensitization

E  hypersensitivity

A  hemopathology

B  histopathology

C  humoralpathology

D  epidemiology

E  immunopathology

A  IgM

B  complement

C  IgE

D  IgG

E  foreign cells

A  Graves’ disease

B  systemic lupus erythematosus

C  metastatic cancer

D  type I diabetes

E  rheumatic fever

A  hypograft

B  allograft

C  xenograft

D    

E  autograft

F  isograft

A  Ingestant

B  None of the choices are correct.

C  Injectant

D  Contactant

E  Inhalant

A  increased sensitivity to pain

B  relaxes vascular smooth muscle

C  constriction of smooth muscle of bronchi and the intestine

D  wheal and flare reaction in skin

E  pruritus and headache

A  type I and type IV

B  type IV only

C  type I only

D  type I, type II, and type III

E  type I, type II, type III, and type IV

A  IgE and mast cells

B  autoantibodies and T cells

C  a transfusion reaction

D  graft rejection

E  a deficiency in T-cell development

A  Diarrhea

B  Rhinitis

C  Rashes

D  Sneezing

E  Contact dermatitis

A  block synthesis of leukotrienes

B  bind to histamine receptors on target organs

C  reverse spasms of respiratory smooth muscles

D  inhibit the activity of lymphocytes

E  relieve inflammatory symptoms

A  Histamine acts on smooth muscle

B  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

C  Prostaglandins cause vasodilation and increased vascular permeability

D  Binding of IgE by the Fc region to mast cells and basophils

E  Degranulation

A  acetylcholine receptors on skeletal muscle

B  cells in thyroid follicles

C  myelin sheath cells of the nervous system

D  sodium pump proteins in the cell membrane

E  acetylcholine receptors on smooth muscle

A  Serum sickness is a systemic response

B  Antigen-antibody complexes are deposited in the basement membrane of epithelial tissues

C  The Arthus reaction is a local response

D  Involves production of IgG and IgE antibodies

E  Involves an immune complex reaction

A  allergic rhinitis

B  atopic dermatitis

C  asthma

D  eczema

E  anaphylaxis

A  Blood transfusion

B  Organ transplantation

C  Both skin graft and organ transplantation

D  Skin graft

E  All of thechoices are correct.

A  degranulation

B  desensitization

C  sensitization

D  tissue matching

E  None of thechoices are correct.

A  Histamine acts on smooth muscle

B  Degranulation

C  Binding of IgE by the Fc region to mast cells and basophils

D  Prostaglandins cause vasodilation and increased vascular permeability

E  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

A  Graft versus host disease

B  Hypogammaglobulinemia

C  Formation of autoantibodies

D  Host rejection of graft

E  None of the choices are correct.

A  Immune complex mediated

B  Anaphylaxis

C  Both anaphylaxis and antibody mediated

D  Antibody mediated

E  Both antibody mediated and immune complex mediated

A  rheumatoid arthritis

B  Graves’ disease

C  myasthenia gravis

D  tuberculin reaction

E  multiple sclerosis

A  platelet-activating factor

B  histamine

C  leukotriene

D  serotonin

E  prostaglandin

A  disulfide bonds between polypeptide chains

B  a variable and constant region on each polypeptide chain

C  two identical light polypeptide chains

D  two identical heavy polypeptide chains

E  four antigen binding sites

A  B cells maturing in bone marrow sites

B  T cells maturing in the thymus

C  All of the choices are correct.

D  hormonal signals that initiate development

E  release of mature lymphocytes to begin migration to various lymphoid organs

A  terminal

B  variable

C  Fab

D  hinge

E  Fc

A  directly destroy target cells

B  secrete antibodies

C  function in allergic reactions

D  activate B cells and other T cells

E  suppress immune reactions

A  engulf and modify antigen to be more immunogenic

B  include dendritic cells

C  All of the choices are correct.

D  include macrophages

E  hold and present processed antigen on their cell membrane surface

A  false

B  true

A  interleukin-1 activating the T helper cell

B  typically a protein antigen

C  All of the choices are correct.

D  binding of T-cell to a site on the antigen

E    

F  binding of T-cell to a class II MHC receptor on a macrophage

A  IgG

B  IgD

C  IgA

D  IgM

E  IgE

A  suppress immune reactions

B  secrete antibodies

C  directly destroy target cells

D  function in allergic reactions

E  activate B cells and other T cells

A  antigen binding site

B  None of the choices are correct.

C  hapten

D  epitope

E  variable region

A  receive and transmit chemical messages among other cells of the system

B  aid in cellular development

C  function in recognition of self molecules

D  All of the choices are correct.

E  are the result of genetic expression

A  are foreign to the immune system

B  are large molecules with a minimum molecular weight of 1,000

C  are cells or large, complex molecules

D  have large polymers made up of repeating subunits

E  have molecular complexity

A  None of the choices are correct.

B  superantigens

C  allergens

D  autoantigens

E  heterophilic antigens

A  helper T cells

B  suppressor T cells

C  delayed hypersensitivity T cells

D  natural killer (NK) cells

E  cytotoxic T cells

A  B cells

B  Plasma cells

C  Antigen-presenting cells

D  Helper T cells

E  Cytotoxic T cells

A  receptors located primarily on macrophages and B cells

B  all HLA antigens

C  All of the choices are correct.

D  certain secreted complement components

E  self receptors recognized by T lymphocytes

A  true

B  false

A  has 10 antigen binding sites

B  is a dimer

C  is the first class synthesized by a plasma cell

D  contains a central J chain

E  can serve as a B-cell receptor

A  cell markers found in some member of a species but not in other members

B  body tissues that the immune system mistakes as foreign

C  bacterial toxins that activate T cells at a 100 times greater rate than other antigens

D  those that evoke allergic reactions

E  None of the choices are correct.

A  false

B  true

A  IgM

B  IgG

C  IgE

D  IgA

E  IgD

A  develop into clones of B and T cells with extreme variations of specificity

B  have membrane receptors that recognize foreign antigens

C  possess MHC antigens for recognizing self

D  All of the choices are correct.

E  gain tolerance to self by destruction of lymphocytes that could react against self

A  All of the choices are correct.

B  located in the thymus gland

C  found on the third chromosome

D    

E  glycoproteins, called MHC antigens, found on all body cells

F  a set of genes that code for MHC glycoproteins

A  leukocytes

B  eosinophils

C  islet of Langerhans cells

D  red blood cells

E  epithelial cells

A  IgG only

B  IgD only

C  IgD and IgE

D  IgM only

E  IgM and IgD

A  Respiratory tract

B  Eyes

C  Digestive tract

D  Urinary tract

E  Skin

A  increases metabolism

B  stimulates hematopoiesis

C  increases phagocytosis

D  reduces the ability of temperature-sensitive organisms to multiply

E  increases the availability of iron

A  Involves barriers at portals of entry
Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

B  Includes chemicals such as lysozyme and lactic acid
Involves recognition of foreign agents by their pathogen-associated molecular patterns

C  Includes chemicals such as lysozyme and lactic acid
Involves barriers at portals of entry
Examples include the ciliated epithelium of the respiratory passages, excretion of urine, and production of tears

D  Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

A  monocytes

B  neutrophils

C  basophils

D  eosinophils

E  lymphocytes

A  cytotoxic T cells

B  primary phagocytes

C  neutrophils

D  macrophages

E  killer T cells

A  platelets

B  dendritic cells

C  eosinophils

D  macrophages

E  mast cells

A  Eosinophils

B  Basophils

C  Neutrophils

D  Lymphocytes

E  Monocytes

A  swelling

B  pain

C  redness

D  chills

E  warmth

A  histamine

B  digestive enzymes

C  antibodies

D  lysozyme

E  antigens

A  monocytes

B  granulocytes

C  None of the choices are correct.

D  leukocytes

E  agranulocytes

A  Mobilize and attract immune components to injury site

B  Destroy microbes

C  Start tissue repair

D  Cause a fever

E  Block further invasion

A  production of only red blood cells

B  loss of blood due to hemorrhaging

C  plugging of broken vessels to stop bleeding

D  production of white blood cells, red blood cells, and platelets

E  migration of white blood cells from the blood out to the tissues

A  tears

B  mucus

C  hairs

D  unbroken skin

E  T cells

A  is the liquid portion of blood in which blood cells are suspended

B  is mostly water

C  contains albumin and globulins

D  All of the choices are correct.

E  contains fibrinogen

A  Rubor—redness

B  Tumor—cancer

C  Calor—warmth

D  Dolar—pain

E  None of these are mismatched.

A  Serotonin causes smooth muscle contraction.

B  Fever could be beneficial to inhibiting the pathogen.

C  Basophils and mast cells release histamine.

D  It can last hours to years.

E  Pyrogens cause vasodilation and increased capillary permeability.

A  respiratory tract

B  skin

C  eyes

D  urinary tract

E  digestive tract

A  Extracellular fluid

B  Bloodstream

C  Lymphatic system

D  Intracellular fluid

A  B cells; T cells

B  Monocytes; basophils

C  Basophils; T cells

D  B cells; neutrophils

E  T cells; B cells

A  Include erythrocytes that, when mature, lose their nuclei

B  Include Kupffer cells

C  After birth, produced in red bone marrow sites

D  Develop from undifferentiated stem cells

E  Include leukocytes that are either granulocytes or agranulocytes

A  motility

B  chemotaxis

C  vasodilation

D  diapedesis

E  phagocytosis

A  thymus

B  lymph nodes

C  GALT

D  spleen

E  tonsils

A  Internal cellular and chemical defenses
Use of drugs and antibiotics
Host defenses due to B and T cells and their products

B  Host defenses due to B and T cells and their products
Use of drugs and antibiotics

C  Host defenses due to B and T cells and their products
Use of drugs and antibiotics
Anatomical and physiological barriers

D  Internal cellular and chemical defenses
Phagocytosis and inflammation
Anatomical and physiological barriers

A  None of the choices are correct.

B  destroys pathogens

C  is toxic to pathogens

D  creates a physical barrier against pathogens

E  physically restricts pathogens to a specific region