Lecture Exam 4 (Ch 12, 13, 14)

A  systemic anaphylactic

B  antibody mediated

C  delayed

D  atopic

E  T-cell mediated

A  maternal Rh ˗ cells enter an Rh + fetus

B  fetal Rh ˗ cells enter an Rh + mother

C  fetal Rh + cells enter an Rh + mother

D  fetal Rh + cells enter an Rh – mother

E  maternal Rh + cells enter an Rh -fetus

A  desensitization

B  hypersensitivity

C  autoimmune disease

D  transfusion reaction

E  immunodeficiency

A  epidemiology

B  humoralpathology

C  histopathology

D  immunopathology

E  hemopathology

A  IgM

B  complement

C  IgG

D  foreign cells

E  IgE

A  Graves’ disease

B  rheumatic fever

C  type I diabetes

D  metastatic cancer

E  systemic lupus erythematosus

A    

B  isograft

C  allograft

D  hypograft

E  xenograft

F  autograft

A  Injectant

B  Contactant

C  Ingestant

D  None of the choices are correct.

E  Inhalant

A  increased sensitivity to pain

B  pruritus and headache

C  constriction of smooth muscle of bronchi and the intestine

D  relaxes vascular smooth muscle

E  wheal and flare reaction in skin

A  type I, type II, type III, and type IV

B  type IV only

C  type I, type II, and type III

D  type I and type IV

E  type I only

A  graft rejection

B  autoantibodies and T cells

C  a transfusion reaction

D  IgE and mast cells

E  a deficiency in T-cell development

A  Rashes

B  Diarrhea

C  Sneezing

D  Contact dermatitis

E  Rhinitis

A  inhibit the activity of lymphocytes

B  block synthesis of leukotrienes

C  relieve inflammatory symptoms

D  bind to histamine receptors on target organs

E  reverse spasms of respiratory smooth muscles

A  Degranulation

B  Histamine acts on smooth muscle

C  Prostaglandins cause vasodilation and increased vascular permeability

D  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

E  Binding of IgE by the Fc region to mast cells and basophils

A  myelin sheath cells of the nervous system

B  acetylcholine receptors on skeletal muscle

C  acetylcholine receptors on smooth muscle

D  cells in thyroid follicles

E  sodium pump proteins in the cell membrane

A  Involves production of IgG and IgE antibodies

B  Involves an immune complex reaction

C  The Arthus reaction is a local response

D  Serum sickness is a systemic response

E  Antigen-antibody complexes are deposited in the basement membrane of epithelial tissues

A  eczema

B  allergic rhinitis

C  asthma

D  anaphylaxis

E  atopic dermatitis

A  Skin graft

B  Both skin graft and organ transplantation

C  Organ transplantation

D  All of thechoices are correct.

E  Blood transfusion

A  sensitization

B  None of thechoices are correct.

C  degranulation

D  desensitization

E  tissue matching

A  Histamine acts on smooth muscle

B  Binding of IgE by the Fc region to mast cells and basophils

C  Degranulation

D  Prostaglandins cause vasodilation and increased vascular permeability

E  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

A  Formation of autoantibodies

B  Host rejection of graft

C  None of the choices are correct.

D  Graft versus host disease

E  Hypogammaglobulinemia

A  Both antibody mediated and immune complex mediated

B  Both anaphylaxis and antibody mediated

C  Immune complex mediated

D  Antibody mediated

E  Anaphylaxis

A  multiple sclerosis

B  tuberculin reaction

C  rheumatoid arthritis

D  Graves’ disease

E  myasthenia gravis

A  platelet-activating factor

B  serotonin

C  histamine

D  leukotriene

E  prostaglandin

A  two identical heavy polypeptide chains

B  disulfide bonds between polypeptide chains

C  two identical light polypeptide chains

D  four antigen binding sites

E  a variable and constant region on each polypeptide chain

A  B cells maturing in bone marrow sites

B  release of mature lymphocytes to begin migration to various lymphoid organs

C  All of the choices are correct.

D  hormonal signals that initiate development

E  T cells maturing in the thymus

A  variable

B  Fab

C  terminal

D  Fc

E  hinge

A  secrete antibodies

B  suppress immune reactions

C  activate B cells and other T cells

D  directly destroy target cells

E  function in allergic reactions

A  engulf and modify antigen to be more immunogenic

B  include macrophages

C  include dendritic cells

D  All of the choices are correct.

E  hold and present processed antigen on their cell membrane surface

A  false

B  true

A    

B  binding of T-cell to a site on the antigen

C  binding of T-cell to a class II MHC receptor on a macrophage

D  typically a protein antigen

E  All of the choices are correct.

F  interleukin-1 activating the T helper cell

A  IgD

B  IgE

C  IgG

D  IgM

E  IgA

A  suppress immune reactions

B  directly destroy target cells

C  function in allergic reactions

D  secrete antibodies

E  activate B cells and other T cells

A  None of the choices are correct.

B  variable region

C  epitope

D  antigen binding site

E  hapten

A  function in recognition of self molecules

B  receive and transmit chemical messages among other cells of the system

C  are the result of genetic expression

D  aid in cellular development

E  All of the choices are correct.

A  are cells or large, complex molecules

B  are large molecules with a minimum molecular weight of 1,000

C  have molecular complexity

D  are foreign to the immune system

E  have large polymers made up of repeating subunits

A  superantigens

B  heterophilic antigens

C  None of the choices are correct.

D  autoantigens

E  allergens

A  suppressor T cells

B  natural killer (NK) cells

C  helper T cells

D  delayed hypersensitivity T cells

E  cytotoxic T cells

A  B cells

B  Antigen-presenting cells

C  Cytotoxic T cells

D  Helper T cells

E  Plasma cells

A  certain secreted complement components

B  self receptors recognized by T lymphocytes

C  All of the choices are correct.

D  receptors located primarily on macrophages and B cells

E  all HLA antigens

A  true

B  false

A  is the first class synthesized by a plasma cell

B  can serve as a B-cell receptor

C  has 10 antigen binding sites

D  is a dimer

E  contains a central J chain

A  None of the choices are correct.

B  those that evoke allergic reactions

C  cell markers found in some member of a species but not in other members

D  bacterial toxins that activate T cells at a 100 times greater rate than other antigens

E  body tissues that the immune system mistakes as foreign

A  false

B  true

A  IgD

B  IgG

C  IgA

D  IgM

E  IgE

A  have membrane receptors that recognize foreign antigens

B  All of the choices are correct.

C  gain tolerance to self by destruction of lymphocytes that could react against self

D  develop into clones of B and T cells with extreme variations of specificity

E  possess MHC antigens for recognizing self

A  found on the third chromosome

B  All of the choices are correct.

C    

D  located in the thymus gland

E  a set of genes that code for MHC glycoproteins

F  glycoproteins, called MHC antigens, found on all body cells

A  leukocytes

B  red blood cells

C  eosinophils

D  islet of Langerhans cells

E  epithelial cells

A  IgD and IgE

B  IgM only

C  IgD only

D  IgG only

E  IgM and IgD

A  Urinary tract

B  Skin

C  Eyes

D  Digestive tract

E  Respiratory tract

A  increases metabolism

B  reduces the ability of temperature-sensitive organisms to multiply

C  increases phagocytosis

D  increases the availability of iron

E  stimulates hematopoiesis

A  Includes chemicals such as lysozyme and lactic acid
Involves recognition of foreign agents by their pathogen-associated molecular patterns

B  Involves barriers at portals of entry
Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

C  Includes chemicals such as lysozyme and lactic acid
Involves barriers at portals of entry
Examples include the ciliated epithelium of the respiratory passages, excretion of urine, and production of tears

D  Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

A  monocytes

B  eosinophils

C  lymphocytes

D  neutrophils

E  basophils

A  cytotoxic T cells

B  killer T cells

C  primary phagocytes

D  macrophages

E  neutrophils

A  platelets

B  macrophages

C  eosinophils

D  mast cells

E  dendritic cells

A  Basophils

B  Lymphocytes

C  Monocytes

D  Eosinophils

E  Neutrophils

A  warmth

B  swelling

C  redness

D  pain

E  chills

A  antibodies

B  lysozyme

C  antigens

D  digestive enzymes

E  histamine

A  leukocytes

B  monocytes

C  None of the choices are correct.

D  granulocytes

E  agranulocytes

A  Cause a fever

B  Mobilize and attract immune components to injury site

C  Destroy microbes

D  Block further invasion

E  Start tissue repair

A  plugging of broken vessels to stop bleeding

B  loss of blood due to hemorrhaging

C  migration of white blood cells from the blood out to the tissues

D  production of white blood cells, red blood cells, and platelets

E  production of only red blood cells

A  hairs

B  mucus

C  unbroken skin

D  T cells

E  tears

A  contains albumin and globulins

B  is the liquid portion of blood in which blood cells are suspended

C  All of the choices are correct.

D  is mostly water

E  contains fibrinogen

A  Dolar—pain

B  Rubor—redness

C  Tumor—cancer

D  None of these are mismatched.

E  Calor—warmth

A  Serotonin causes smooth muscle contraction.

B  Basophils and mast cells release histamine.

C  Pyrogens cause vasodilation and increased capillary permeability.

D  Fever could be beneficial to inhibiting the pathogen.

E  It can last hours to years.

A  eyes

B  respiratory tract

C  digestive tract

D  skin

E  urinary tract

A  Intracellular fluid

B  Extracellular fluid

C  Bloodstream

D  Lymphatic system

A  B cells; T cells

B  B cells; neutrophils

C  Monocytes; basophils

D  Basophils; T cells

E  T cells; B cells

A  Develop from undifferentiated stem cells

B  Include leukocytes that are either granulocytes or agranulocytes

C  Include erythrocytes that, when mature, lose their nuclei

D  After birth, produced in red bone marrow sites

E  Include Kupffer cells

A  phagocytosis

B  chemotaxis

C  diapedesis

D  motility

E  vasodilation

A  thymus

B  tonsils

C  spleen

D  lymph nodes

E  GALT

A  Internal cellular and chemical defenses
Use of drugs and antibiotics
Host defenses due to B and T cells and their products

B  Host defenses due to B and T cells and their products
Use of drugs and antibiotics
Anatomical and physiological barriers

C  Host defenses due to B and T cells and their products
Use of drugs and antibiotics

D  Internal cellular and chemical defenses
Phagocytosis and inflammation
Anatomical and physiological barriers

A  physically restricts pathogens to a specific region

B  destroys pathogens

C  creates a physical barrier against pathogens

D  is toxic to pathogens

E  None of the choices are correct.