Lecture Exam 1

A  Paracrine

B  muscle cell

C  collagen cells

D  epithelial cells

A  TRUE

B  FALSE

A  A new set of effects unlike those of heroin alone

B  An increase in the effects of heroin

C  The same effects from heroin plus additional effects of naloxone

D  A decrease in the effects of heroin

A  TRUE

B  FALSE

A  It is the first messenger that binds to the integral membrane protein receptor.

B  Along with diacylglycerol, it activates protein kinase C.

C  It phosphorylates cell proteins.

D  It splits and activates G-protein subunits.

E  It binds to the endoplasmic reticulum and causes therelease ofinositol trisphosphate

A  Cyclic AMP

B  Glucose

C  Sodium

D  Thyroid hormone

E  Protein kinase

A  Only hydrophilic first-messenger molecules can activate second-messenger molecules within the cell cytosol.

B  Some cellular receptors have such low affinity for chemical ligands that it can require a million or more molecules to activate them.

C  A single first-messenger molecule activates multiple second-messenger molecules, each of which activate thousands of enzymes.

D  When the extracellular concentration of a chemical messenger reaches a very high level, it overwhelms transporter molecules and the chemical floods into the cell.

A  TRUE

B  FALSE

A  Increasing the availability of phosphodiesterase molecules

B  Increasing the expression of Camp

C  Inhibiting phosphodiesterase activity

D  Acting as an agonist on the receptor for epinephrine, a hormone that increases heart contractility

E  Decreasing the activity of cAMP-dependent protein kinase

A  The activated receptor complex stimulates production of two different second messengers.

B  Cyclic AMP-dependent protein kinase activates two kinds of enzymes.

C  Cyclic AMP directly activates enzymes that catabolize glycogen and fat.

D  Epinephrine is binding to two types of receptors in the plasma membrane.

A  There are two types of receptors for epinephrine that use the same second-messenger system.

B  There are two types of epinephrine receptors with different affinities for epinephrine that use two different second-messenger systems.

C  At higher concentrations epinephrine can pass through the plasma membrane and directly stimulate contraction within the cell.

D  There is one type of epinephrine receptor that uses two second-messenger systems.

A  TRUE

B  FALSE

A  FALSE

B  TRUE

A  FALSE

B  TRUE

A  Solutes

B  Lipid molecules

C  Water

D  Charged particles

E  Glucose

A  FALSE

B  TRUE

A  Substance X and Substance Y will diffuse at the same rate, as they are of equal size and concentration.

B  Substance Y will diffuse faster.

C  Substance X will diffuse faster.

A  FALSE

B  TRUE

A  TRUE

B  FALSE

A  Hypertonic solutions are always hyperosmotic.

B  The term “osmolarity” refers to the osmotic properties of a solution, regardless of its tonicity.

C  Isotonic solutions are always isoosmotic.

D  Hypoosmotic solutions are always hypotonic

E  The term “tonicity” refers to the effect that a solution has on the degree of stretch or shrinking of the cell membrane.

A  FALSE

B  TRUE

A  Facilitated diffusion of glucose to the bloodstream from the lumen

B  Active transport of Na + from the lumen to the basolateral side

C  Tightening the tight junctions between epithelial cells

D  Opening of aquaporins on the apical membrane

E  Active transport of H + from the basolateral side to the lumen

A  are polymers of ATP that store large amounts of energy.

B  can be carbohydrate molecules.

C  have names generally ending in the suffix “-ose.”

D  are broken down during chemical reactions they catalyze.

E  are catalysts in chemical reactions.

A  water.

B  proteins and glycocalyx.

C  phospholipids and nucleic acids.

D  cytosol.

E  phospholipids and proteins.

A  They produce effects similar to allosteric modulation.

B  They remove phosphate groups from proteins.

C  They perform the opposite function as phosphatases.

D  They add phosphate groups to proteins.

E  They use ATP to carry out their reactions.

A  FALSE

B  TRUE

A  It binds to a different binding site on the protein, altering the protein shape so that a ligand cannot bind.

B  It decreases the amount of ligand required to activate the protein.

C  It blocks the binding of the ligand to its binding site and prevents activation of the protein.

D  When present, it increases the binding of a ligand to its receptor.

A  FALSE

B  TRUE

A  FALSE

B  TRUE

A  2 molecules of ATP, 2 molecules of water, and 2 molecules of lactate

B  2 molecules of pyruvate, 2 molecules of lactate, and 2 ATP

C  2 molecules of pyruvate, 2 molecules of water, and 2 NADH

D  2 molecules of NADH and 2 molecules of water

E  2 molecules of pyruvate and 36 molecules of ATP

A  TRUE

B  FALSE

A  Cholesterol will associate with adjacent phospholipid molecules and stay near them.

B  Cholesterol will be excluded from the bilayer and will no longer be associated with phospholipids because they have different properties.

C  All of the molecules will move freely in the lipid bilayer.

D  Cholesterol will migrate away from phospholipids and toward proteins.

A  Takes place in the cytosol of cells

B  Requires more energy than is produced by the catabolism of the same fatty acid

C  Results in molecules with an even number of carbon atoms only

D  Begins with a molecule of acetyl coenzyme A

E  The enzymes that catalyze it are in the same location as those that mediate fatty acid catabolism

A  FALSE

B  TRUE

A  TRUE

B  FALSE

A  TRUE

B  FALSE

A  FALSE

B  TRUE

A  Decrease blood glucose level

B  No effect on blood glucose level

C  Increase blood glucose level

A  Disulfide bridges

B  Hydrogen bonds

C  Ionic bonds

D  Hydrophobic interactions

E  You are likely to find all of these within a single protein.

A  FALSE

B  TRUE

A  hydrophobic.

B  hydrophilic.

C  bipolar.

D  unipolar.

E  amphipathic.

A  The number of neutrons

B  The number of electrons

C  The number of bonds it can form

D  The number of protons

E  The ratio of protons to electrons

A  Covalent bonds between two cysteine amino acids

B  Van der Waals forces

C  Hydrogen bonds

D  Covalent bonds between purine and pyrimidine bases

E  Ionic bonds

A  TRUE

B  FALSE

A  TRUE

B  FALSE

A  They cease to occur when a person is in a dark environment.

B  They repeat approximately every 24 hours, like daily spikes in hormone secretion.

C  They cease to occur when a person is in a dark environment.

D  They are cyclical, like the 28-day female menstrual cycle.

E  They are voluntary rhythms, like the time you decide to eat lunch each day.

A  TRUE

B  FALSE

A  After eating a large batch of salty popcorn, levels of salt in the urine increase.

B  As age increases, the amount of calcium in bones tends to decrease.

C  After going outside on a hot day, the core body temperature increases.

D  A person who becomes very nervous begins to sweat profusely.

E  Increasing the size of fast-food restaurant portions causes body weight to increase.

A  FALSE

B  TRUE

A  Feedforward regulation

B  Positive feedback

C  Developmental acclimatization

D  Evolution

E  Physiological acclimatization

A  TRUE

B  FALSE

A  Receptor, afferent pathway, integrating center, efferent pathway, effector

B  Effector, efferent pathway, integrating center, afferent pathway, receptor

C  Receptor, efferent pathway, integrating center, afferent pathway, effector

D  Integrating center, receptor, afferent pathway, efferent pathway, effector

E  Effector, afferent pathway, integrating center, efferent pathway, receptor